NCT07306286 2025-12-29
Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy
Ruijin Hospital
Phase 2 Recruiting
Clinical Trials
28 trialsNCT04693377 2025-10-27
Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial
M.D. Anderson Cancer Center
Phase NA Recruiting
NCT07070700 2025-08-12
CASTLE-ZS-02
Fudan University
Phase 2 Recruiting
NCT02380443 2025-05-16
AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer
Mirror Biologics, Inc.
Phase 2 Completed
NCT05010668 2025-02-21
Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma
Fudan University
Phase 2 Completed
NCT05302921 2025-01-01
Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors
Children's National Research Institute
Phase 2 Completed
NCT04248582 2024-08-05
Cryotherapy for Locally Advanced Esophageal Cancer
Hunter Holmes Mcguire Veteran Affairs Medical Center
Phase 1 Active not recruiting
NCT06530784 2024-07-31
Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
Phase 2 Not yet recruiting
NCT06265350 2024-02-20
Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases
Sun Yat-sen University
Phase NA Recruiting
NCT05893056 2023-06-27
CASTLE-09
Fudan University
Phase 2 Unknown
NCT00002997 2023-06-15
Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer
Eastern Cooperative Oncology Group
Phase 2 Completed
NCT02821754 2023-03-28
A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)
National Institutes of Health Clinical Center (CC)
Phase 2 Completed
NCT05781074 2023-03-24
CASTLE-08
Fudan University
Phase 2 Unknown
NCT01293448 2022-04-28
Evaluation of Balloon-based Cryoablation of Human Esophageal Epithelium
Pentax Medical
Phase NA Completed
NCT04724226 2021-09-05
C-couple
Sun Yat-sen University
Phase 2 Unknown
NCT03183219 2020-07-13
Safety and Efficiency of γδ T Cell Against Liver Cancer
Fuda Cancer Hospital, Guangzhou
Phase 1/2 Completed
NCT01065441 2020-01-22
Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer
Mirror Biologics, Inc.
Phase 1/2 Completed
NCT01741038 2020-01-22
AlloStim® In-Situ Vaccine in Pre-Treated Metastatic Colorectal Cancer
Mirror Biologics, Inc.
Phase 2/3 Withdrawn
NCT01853618 2019-12-10
Tremelimumab With Chemoembolization or Ablation for Liver Cancer
National Institutes of Health Clinical Center (CC)
Phase 1/2 Completed
NCT02843581 2019-09-12
Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer
Fuda Cancer Hospital, Guangzhou
Phase 1/2 Completed
NCT02843802 2019-09-12
Combination of Cryosurgery and NK Immunotherapy for Advanced Liver Cancer
Fuda Cancer Hospital, Guangzhou
Phase 1/2 Completed
NCT02849015 2019-09-12
Combination of Cryosurgery and NK Immunotherapy for Tumors in Transplanted Liver
Fuda Cancer Hospital, Guangzhou
Phase 1/2 Completed
NCT03239184 2019-01-25
Bioinformation Therapy for Pancreatic Cancer
Fuda Cancer Hospital, Guangzhou
Phase 2/3 Completed
NCT00499733 2019-01-18
Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase EARLY_PHASE1 Terminated
NCT03223142 2017-07-21
SMTATS
Shanghai Zhongshan Hospital
Phase NA Unknown
NCT02545556 2016-08-29
Liver Cancer HepaSphere Combined With Cryosurgery
Fuda Cancer Hospital, Guangzhou
Phase 1/2 Completed
NCT00002655 2013-07-22
Cryosurgery in Treating Patients With Liver Cancer or Liver Metastases
University of Colorado, Denver
Phase 2 Completed
NCT00899210 2011-05-17
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer
National Cancer Institute (NCI)
Completed