Clinical Trials Browser

NCT07306286 2025-12-29

Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Phase 2 Recruiting

20 enrolled

Gastrointestinal

Pancreatic Adenocarcinoma Locally Advanced

NCT04693377 2025-10-27

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Phase NA Recruiting

40 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT07070700 2025-08-12

CASTLE-ZS-02

Phase 2 Recruiting

56 enrolled

Gastrointestinal

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT05010668 2025-02-21

Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma

Phase 2 Completed

28 enrolled

Gastrointestinal

Cholangiocarcinoma

NCT05302921 2025-01-01

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Phase 2 Completed

5 enrolled

CNSDermatologicGastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Melanoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT06530784 2024-07-31

Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma

Phase 2 Not yet recruiting

36 enrolled

Gastrointestinal

Carcinoma, Hepatocellular

NCT06265350 2024-02-20

Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases

Phase NA Recruiting

80 enrolled

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

NCT05893056 2023-06-27

CASTLE-09

Phase 2 Unknown

25 enrolled

Gastrointestinal

Gastric Cancer Metastatic to Liver

NCT05781074 2023-03-24

CASTLE-08

Phase 2 Unknown

25 enrolled

Gastrointestinal

Advanced Biliary Tract Cancer

NCT04724226 2021-09-05

C-couple

Phase 2 Unknown

34 enrolled

Gastrointestinal

Carcinoma, Hepatocellular

NCT03183219 2020-07-13

Safety and Efficiency of γδ T Cell Against Liver Cancer

Phase 1/2 Completed

30 enrolled

Gastrointestinal

Liver Neoplasms

NCT02843581 2019-09-12

Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer

Phase 1/2 Completed

60 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT02843802 2019-09-12

Combination of Cryosurgery and NK Immunotherapy for Advanced Liver Cancer

Phase 1/2 Completed

30 enrolled

Gastrointestinal

Liver Neoplasms

NCT02849015 2019-09-12

Combination of Cryosurgery and NK Immunotherapy for Tumors in Transplanted Liver

Phase 1/2 Completed

20 enrolled

Gastrointestinal

Carcinoma, Hepatocellular

NCT03239184 2019-01-25

Bioinformation Therapy for Pancreatic Cancer

Phase 2/3 Completed

120 enrolled

Gastrointestinal

Unresectable Pancreatic Cancer

NCT00499733 2019-01-18

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Phase EARLY_PHASE1 Terminated

19 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Osteosarcoma, Tongue Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Intraocular Lymphoma

NCT03223142 2017-07-21

SMTATS

Phase NA Unknown

100 enrolled

Gastrointestinal

Liver Neoplasms, Neoplasm Metastasis

NCT02545556 2016-08-29

Liver Cancer HepaSphere Combined With Cryosurgery

Phase 1/2 Completed

60 enrolled

Gastrointestinal

Liver Neoplasms

NCT00002655 2013-07-22

Cryosurgery in Treating Patients With Liver Cancer or Liver Metastases

Phase 2 Completed

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis