Clinical Trials Browser

Phase 1 × Metformin × Gastrointestinal × Clear all

NCT02336087 2026-02-04

Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

Phase 1 Active not recruiting

Gastrointestinal

Pancreatic Adenocarcinoma

NCT03889795 2025-10-20

Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

Phase 1 Active not recruiting

GastrointestinalOther solid neoplasm

Advanced Pancreatic Cancer

NCT02048384 2021-04-12

A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer

Phase 1 Completed

Gastrointestinal

Adenocarcinoma, Neoplasm Metastasis, Pancreatic Neoplasms

NCT01816659 2015-11-18

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Phase 1 Terminated

Gastrointestinal

Colorectal Neoplasms

NCT01954732 2015-07-15

Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery

Phase 1 Withdrawn

Gastrointestinal

Pancreatic Neoplasms

NCT01440127 2015-03-26

Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers

Phase 1 Terminated

Gastrointestinal

Colonic Neoplasms