NCT02437656 2026-03-16
METCAP
Centre Oscar Lambret
Phase 2 Completed
Clinical Trials
36 trialsNCT02336087 2026-02-04
Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
City of Hope Medical Center
Phase 1 Active not recruiting
NCT03889795 2025-10-20
Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
University of Toledo
Phase 1 Active not recruiting
NCT06687876 2025-07-10
MEMENTO
Amsterdam UMC, location VUmc
Phase 2 Recruiting
NCT04114136 2025-02-10
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
University of Pittsburgh
Phase 2 Recruiting
NCT05158374 2025-02-06
Molecular Effects of Aspirin & Metformin on Colonic Epithelium
University of Edinburgh
Phase NA Withdrawn
NCT03047837 2025-01-27
ASAMET
Ente Ospedaliero Ospedali Galliera
Phase 2 Terminated
NCT03800602 2024-09-05
Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer
Emory University
Phase 2 Completed
NCT02431676 2024-08-28
SPIRIT
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 2 Completed
NCT06030622 2024-04-19
C3
State University of New York - Downstate Medical Center
Phase 1/2 Recruiting
NCT04033107 2023-09-28
High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors
Zhongnan Hospital
Phase 2 Unknown
NCT02201381 2022-07-18
METRICS
Health Clinics Limited
Phase 3 Withdrawn
NCT01725490 2021-09-20
The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Yonsei University
Phase 2 Completed
NCT01666730 2021-08-10
Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer
Case Comprehensive Cancer Center
Phase 2 Completed
NCT01210911 2021-04-21
GEM
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Phase 2 Completed
NCT02048384 2021-04-12
A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Completed
NCT02153450 2020-06-26
Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer
Case Comprehensive Cancer Center
Phase EARLY_PHASE1 Completed
NCT02614339 2019-09-18
Effect of Adjunctive Metformin on Recurrence of Non-DM Colorectal Cancer Stage II High-risk/ III Colorectal Cancer
Yonsei University
Phase 3 Unknown
NCT01312467 2019-03-05
Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI
National Cancer Institute (NCI)
Phase 2 Completed
NCT03833466 2019-02-15
ECMTPneo
Peking University
Phase 2 Unknown
NCT02005419 2019-02-05
Metformin Combined With Gemcitabine as Adjuvant Therapy for Pancreatic Cancer After Curative Resection
Fudan University
Phase 2 Completed
NCT01523639 2018-12-19
G-LUCAS
Austrian Breast & Colorectal Cancer Study Group
Phase 2 Terminated
NCT01926769 2018-05-15
A Phase II Study to Determine the Safety and Efficacy of Second-line Treatment With Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the Second Line Threatment of Advanced Colorectal Cancer
Gachon University Gil Medical Center
Phase 2 Terminated
NCT02978547 2018-01-18
Metformin 001
British Columbia Cancer Agency
Phase 2 Unknown
NCT02473094 2017-11-28
NEOMETRE
University of Campinas, Brazil
Phase 2 Terminated
NCT01930864 2017-06-22
Metformin Plus Irinotecan for Refractory Colorectal Cancer
Barretos Cancer Hospital
Phase 2 Unknown
NCT01488552 2016-08-18
Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer
Pancreatic Cancer Research Team
Phase 1/2 Completed
NCT01632020 2016-07-11
Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth
University of Arkansas
Phase 2 Terminated
NCT01465113 2016-03-10
Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus
Case Comprehensive Cancer Center
Phase EARLY_PHASE1 Completed
NCT02672488 2016-02-03
Metformin Plus Sorafenib for Advanced HCC
Tianjin Medical University Cancer Institute and Hospital
Phase 2 Unknown
NCT01816659 2015-11-18
An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT01954732 2015-07-15
Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery
Case Comprehensive Cancer Center
Phase 1 Withdrawn
NCT01167738 2015-04-24
PACT-17
IRCCS San Raffaele
Phase 2 Terminated
NCT01941953 2015-04-08
Metformin and 5-fluorouracil for Refractory Colorectal Cancer.
Instituto do Cancer do Estado de São Paulo
Phase 2 Completed
NCT01440127 2015-03-26
Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers
Tufts Medical Center
Phase 1 Terminated
NCT01447927 2014-07-21
Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus
National Cancer Institute (NCI)
Phase 2 Completed