Clinical Trials

110 enrolled 21 charts

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT04751370 2026-03-18

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

31 enrolled

Rectal Neoplasms

NCT07467590 2026-03-12

TRIUNITE-07

33 enrolled

Colorectal Neoplasms

NCT03322267 2026-03-06

Adjuvant Pembrolizumab for Patients With Locally Advanced Esophageal Squamous Cell Carcinoma at High Risk of Recurrence

26 enrolled 6 charts

Esophageal Squamous Cell Carcinoma

NCT07448142 2026-03-04

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

50 enrolled

Colorectal Neoplasms

NCT07039162 2026-02-27

Study of Tislelizumab Combined With Chemoradiotherapy and Surgery for Unresectable Esophageal Squamous Cell Carcinoma

45 enrolled

Esophageal Squamous Cell Carcinoma

NCT04643366 2026-01-27

Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer

54 enrolled

Rectal Neoplasms

NCT05009069 2026-01-22

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

58 enrolled

Rectal Neoplasms

NCT03257163 2026-01-20

Pembrolizumab, Capecitabine, and Radiation Therapy in Treating Patients With Mismatch-Repair Deficient and Epstein-Barr Virus Positive Gastric Cancer

40 enrolled

Stomach Neoplasms

NCT00335816 2026-01-14

Radiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal Cancer

248 enrolled

Rectal Neoplasms, Colorectal Neoplasms

NCT03104439 2026-01-12

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

84 enrolled

Pancreatic Neoplasms

NCT03921684 2026-01-05

Trial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer Patients

29 enrolled

Rectal Neoplasms

NCT07291401 2025-12-18

Radiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC

108 enrolled

Rectal Cancer Patients

NCT07179900 2025-12-11

Radiotherapy Combined With QL1706 and Bevacizumab for Unresectable Non-metastatic Hepatocellular Carcinoma

60 enrolled

Carcinoma, Hepatocellular

NCT07274774 2025-12-10

SBRT Plus Systemic Therapy vs Systemic Therapy Alone in BCLC C Hepatocellular Carcinoma

184 enrolled

Carcinoma, Hepatocellular, Neoplasm Metastasis

NCT06994299 2025-11-18

PRISM

Phase 2 Withdrawn

Carcinoma, Hepatocellular

NCT06281886 2025-11-17

Induction Immuno-chemotherapy and Concurrent Chemoradiotherapy With or Without Apatinib in Unresectable, Locally Advanced Esophageal Squamous Cell Carcinoma

170 enrolled

Esophageal Squamous Cell Carcinoma

NCT07086469 2025-11-17

Surufatinib in Combination With Neoadjuvant Chemo-immunotherapy and Concurrent Chemoradiotherapy for Patients With Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma

69 enrolled

Esophageal Squamous Cell Carcinoma

NCT01972919 2025-10-27

MR Guided Phase II Radiotherapy Dose Escalation in Unresectable Non-Metastatic Pancreatic Cancer

23 enrolled 8 charts

Pancreatic Neoplasms

NCT03161522 2025-10-23

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

100 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT01512589 2025-10-10

Proton Beam Therapy (PBT) Versus Intensity-Modulated Radiation Therapy (IMRT) Trial

147 enrolled

Adenocarcinoma, Carcinoma, Squamous Cell, Esophageal Neoplasms

NCT07196540 2025-09-29

IP rmhTNF-NC + Tislelizumab + Palliat RT for GIT Tumor Malignant Ascites After Failed Std Tx

78 enrolled

Digestive System Neoplasms

NCT07183865 2025-09-19

Hypofractionated Radiotherapy Combined With NALIRIF, PD-1 Antibody in Locally Recurrent Rectal Cancer(NOVELTY-R)

44 enrolled

Locally Recurrent Rectal Cancer

NCT07165847 2025-09-10

Neoadjuvant Radiotherapy Plus Tegafur, Oxaliplatin and Iparomlimab and Tuvonralimab in Resectable Gastric and GE-junction Cancer : A Randomized, Two-arm, Prospective Trial (TRIUNITE-05)

40 enrolled

Stomach Neoplasms

NCT07162714 2025-09-09

STAR

30 enrolled

Rectal Neoplasms

NCT06884670 2025-09-08

Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study

130 enrolled

Rectal Neoplasms

NCT05024097 2025-08-27

PANTHER

43 enrolled

Rectal Neoplasms

NCT05515796 2025-08-24

Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors

200 enrolled

Rectal Neoplasms, Stomach Neoplasms

NCT06149689 2025-08-07

PTCA199-7

30 enrolled

Pancreatic Adenocarcinoma

NCT04594772 2025-07-02

Adaptive Approach to Neoadjuvant Therapy to Maximize Resection Rates for Pancreatic Adenocarcinoma

32 enrolled

Pancreatic Neoplasms

NCT06949111 2025-07-01

Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color）

128 enrolled

Colonic Neoplasms

NCT06356584 2025-06-26

Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases

62 enrolled

Colorectal Neoplasms

NCT06780787 2025-06-26

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

26 enrolled

Rectal Neoplasms

NCT06370663 2025-06-25

First-line Treatment for Unresectable Locally Advanced Distal Cholangiocarcinoma Combining Radiotherapy and HAIC

Phase 2 Terminated

1 enrolled

Cholangiocarcinoma

NCT06446726 2025-06-06

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

30 enrolled

Esophageal Squamous Cell Carcinoma

NCT00324415 2025-05-30

Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer

45 enrolled 17 charts

Anal Canal Carcinoma, Anus Neoplasms

NCT06949098 2025-05-29

Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal Cancer

60 enrolled

Rectal Neoplasms

NCT06991465 2025-05-28

Hypo-OPRA

35 enrolled

Colorectal Neoplasms

NCT06988956 2025-05-25

Nimotuzumab Plus Definite Chemoradiotherapy(dCRT) in Elderly Patients With Esophageal Squamous Cell Carcinoma

95 enrolled

Esophageal Squamous Cell Carcinoma

NCT06946849 2025-04-27

SED-RO-ICC

76 enrolled

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT06637163 2025-04-17

Benmelstobart Combined With Radiochemotherapy as Neoadjuvant Treatment Iin ESCC

100 enrolled

Esophageal Squamous Cell Carcinoma

NCT06919510 2025-04-09

A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal Cancer

90 enrolled

Rectal Neoplasms

NCT04866836 2025-03-21

A Study of Tislelizumab Combined With Radiotherapy as the Second-line Treatment of Advanced Biliary Malignant Tumors

Phase 2 Terminated

20 enrolled

Cholangiocarcinoma

NCT06870942 2025-03-11

Efficacy and Safety of Radiotherapy in Oligoprogressive HCC Following First-line PD-1 Therapy

35 enrolled

Carcinoma, Hepatocellular

NCT03541486 2025-03-10

XACT-PANC-2

Phase 2 Withdrawn

Pancreatic Neoplasms

NCT04503694 2025-03-05

REGINA

72 enrolled

Rectal Neoplasms

NCT01643070 2025-02-25

Preoperative CRT With or Without Induction Chemotherapy for Rectal Cancer With Liver Metastases

38 enrolled 16 charts

Rectal Neoplasms

NCT06791148 2025-01-24

Low-dose Radiotherapy Combined With Chemotherapy and AK112 as Second-line Treatment in Patients With Advanced G/GEJ Cancer

45 enrolled

Stomach Neoplasms

NCT03565029 2024-12-27

NO-CUT

180 enrolled

Colonic Neoplasms, Rectal Neoplasms

NCT06709417 2024-11-29

A Phase II Clinical Study of Sintilimab Combined with Chemotherapy Followed by Concurrent Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) (NICE-CS)

52 enrolled