Clinical Trials

15 enrolled

Colorectal Neoplasms

NCT06408220 2026-03-13

Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer

Phase NA Recruiting

240 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Stomach Neoplasms

NCT05269381 2026-03-12

PNeoVCA

Phase 1/2 Recruiting

132 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06349642 2026-03-12

ELEPHAS-04

Recruiting

324 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Clear-cell metastatic renal cell carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Neoplasm Metastasis, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06269978 2026-03-10

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer

24 enrolled

Colorectal Neoplasms

NCT06651580 2026-03-04

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

Recruiting

1,600 enrolled

Pancreatic Neoplasms, Pancreatitis, Pancreatitis, Chronic

NCT04975516 2026-03-03

Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer

Phase 2 Terminated

3 enrolled

Phase NA Not yet recruiting

Pancreatic Neoplasms

NCT07439484 2026-02-27

PRECISE

20 enrolled

Clinical Stage I Esophageal Adenocarcinoma American Joint Committee on Cancer (AJCC) v8

NCT03942328 2026-02-24

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Phase 1/2 Recruiting

85 enrolled

Phase 2 Active not recruiting

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT06178588 2026-02-24

Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma

15 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT06855524 2026-02-24

Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological Cancer

34 enrolled

Phase 3 Active not recruiting

Gastrointestinal Neoplasms

NCT03186898 2026-02-13

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

186 enrolled

Phase 2 Not yet recruiting

Carcinoma, Hepatocellular

NCT07405086 2026-02-12

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

160 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT07407647 2026-02-12

Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer

GastrointestinalGynecologic

25 enrolled

Anus Neoplasms, Uterine Cervical Neoplasms, Rectal Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT06968195 2026-02-10

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

Phase 1 Suspended

24 enrolled

Carcinoma, Hepatocellular

NCT07214298 2026-02-06

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Phase 1/2 Recruiting

35 enrolled

Pancreatic Neoplasms

NCT05791448 2026-02-02

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Carcinoma, Hepatocellular

NCT06958328 2026-02-02

LAP100

Phase 3 Recruiting

356 enrolled

Pancreatic Neoplasms

NCT06381154 2026-01-30

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advanced or Metastatic Pancreatic Cancer

25 enrolled

Phase 1/2 Active not recruiting

Pancreatic Neoplasms

NCT05672316 2026-01-28

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

28 enrolled

Phase 1 Not yet recruiting

Colorectal Neoplasms

NCT07363408 2026-01-23

Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer

30 enrolled

Phase 2 Active not recruiting

Colorectal Neoplasms

NCT04550481 2026-01-21

Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study

45 enrolled

Phase 2 Active not recruiting

Carcinoma, Hepatocellular, Non-alcoholic Fatty Liver Disease

NCT04767984 2026-01-21

Testing Atorvastatin to Lower Colon Cancer Risk in Longstanding Ulcerative Colitis

42 enrolled

Colitis, Ulcerative, Colorectal Neoplasms

NCT03801876 2026-01-14

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Phase 3 Recruiting

300 enrolled

Clinical Stage I Esophageal Adenocarcinoma AJCC v8

NCT06073431 2026-01-09

LOTUS

Recruiting

800 enrolled

GastrointestinalThoracic

Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT07326150 2026-01-08

Construction of a Predictive Model for the Efficacy of Chemoprevention Combined With Targeted Therapy in Pancreatic Cancer

Active not recruiting

70 enrolled

Phase 2 Enrolling by invitation

Pancreatic Neoplasms

NCT07139951 2025-12-31

Hyperthermic Intraperitoneal Chemotherapy With Cisplatin and Paclitaxel for the Treatment of Patients With Gastric and Gastroesophageal Junction Adenocarcinoma at High Risk of Peritoneal Recurrence

16 enrolled

DermatologicGastrointestinalGenitourinaryGynecologic

Clinical Stage I Gastric Cancer AJCC v8

NCT06626256 2025-12-24

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Phase 1 Withdrawn

Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06420349 2025-12-22

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Phase 1 Terminated

7 enrolled

Cholangiocarcinoma, Klatskin Tumor

NCT07226856 2025-12-22

BMS-986340 in Combination With Nivolumab, Gemcitabine and Nab-paclitaxel for the Treatment of Metastatic and Recurrent Pancreatic Adenocarcinoma

43 enrolled

Pancreatic Neoplasms

NCT05802056 2025-12-19

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

15 enrolled

Phase NA Enrolling by invitation

Stomach Neoplasms

NCT06744595 2025-12-12

Personalized Education and Genetic Counseling to Increase Genetic Testing in Patients With a Known Family History of Pancreatic Cancer

40 enrolled

Phase 3 Not yet recruiting

Pancreatic Neoplasms

NCT07271355 2025-12-09

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

129 enrolled

Appendiceal Neoplasms, Colorectal Neoplasms

NCT07271823 2025-12-09

Establishment of a Predictive Model for Immunotherapy Response in Pancreatic Cancer

Active not recruiting

100 enrolled

Pancreatic Cancer Non-resectable

NCT06731894 2025-12-05

Phytocannabinoids for Reducing Chronic Chemotherapy-Induced Peripheral Neuropathy in Breast and Colon Cancer Survivors

Phase NA Active not recruiting

120 enrolled

BreastGastrointestinal

Breast Neoplasms, Colonic Neoplasms

NCT06132087 2025-11-25

PROACTIVE: Surgical Resection Outcomes in Locally Advanced and Unresectable Pancreatic Cancer After Neoadjuvant Chemotherapy

2 enrolled

Phase 1/2 Active not recruiting

Locally Advanced Pancreatic Adenocarcinoma

NCT05627635 2025-11-10

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

20 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06058663 2025-10-20

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

16 enrolled

Cholangiocarcinoma

NCT05930496 2025-09-25

Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors

Phase NA Recruiting

30 enrolled

Colorectal Neoplasms

NCT07140679 2025-09-25

Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer

40 enrolled

Colonic Neoplasms

NCT05722288 2025-08-29

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

GastrointestinalGenitourinary

60 enrolled

Prostatic Neoplasms, Rectal Neoplasms

NCT07125729 2025-08-15

Minimal Residual Disease Testing for the Early Detection of Cancer Recurrence in Resectable Stage II-IV Colorectal Cancer Patients

Phase NA Recruiting

150 enrolled

Colorectal Neoplasms

NCT06423326 2025-07-30

Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

Phase EARLY_PHASE1 Not yet recruiting

Pancreatic Neoplasms

NCT07089940 2025-07-29

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

12 enrolled

Pancreatic Neoplasms

NCT06834126 2025-07-18

Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

Phase 1/2 Not yet recruiting

Rectal Neoplasms

NCT07042919 2025-06-29

Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer

53 enrolled

Fibrosis, Carcinoma, Hepatocellular

NCT06780787 2025-06-26

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

26 enrolled

Rectal Neoplasms

NCT04856046 2025-06-12

Detection of Plasma DNA Methylation in Peripheral Blood From Patients With Resectable Liver Cancer

Active not recruiting

Phase EARLY_PHASE1 Terminated

Resectable Hepatocellular Carcinoma

NCT05841706 2025-06-10

Red Blood Cell Transfusion Thresholds for Improved Quality of Life for Patients Undergoing a Pancreatectomy for Pancreatic Cancer

1 enrolled