Clinical Trials Browser

Completed × aflibercept × Gastrointestinal × Clear all

NCT02159989 2025-10-20

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 1 Completed

83 enrolled 21 charts

GastrointestinalGynecologic

Fibrolamellar hepatocellular carcinoma, Adenoma, Islet Cell, Neoplasm Metastasis, Ovarian Neoplasms

NCT03186326 2025-06-29

SAMCO

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT01652196 2025-02-05

Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer

Phase 2 Completed

56 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03730558 2025-01-22

ZETA

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis

NCT02384759 2024-07-10

FOLFA

Phase 2 Completed

117 enrolled 12 charts

Gastrointestinal

Colorectal Neoplasms

NCT00407654 2024-03-04

VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer

Phase 2 Completed

75 enrolled 15 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT03530267 2024-02-23

ELDERLY

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03279289 2023-04-13

AFEMA

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03043729 2023-02-06

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms

NCT02181556 2021-06-07

Efficacy and Safety of Aflibercept in Combination With FOLFIRI Chemotherapy as 1st Line Treatment for Patients With Metastatic Colorectal Cancer

Phase 2 Completed

41 enrolled 8 charts

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT02340949 2021-05-03

RIA

Phase 2 Completed

180 enrolled 15 charts

Gastrointestinal

Rectal Neoplasms

NCT01747551 2020-02-10

FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer

Phase 2 Completed

64 enrolled 11 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT01661972 2018-10-29

X-TRAP

Phase 1/2 Completed

63 enrolled 12 charts

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT01571284 2018-04-17

Safety and Quality of Life Study of Aflibercept in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen

Phase 3 Completed

781 enrolled 28 charts

Gastrointestinal

Colorectal Cancer Metastatic

NCT01843725 2018-01-31

MOMENTUM1

Phase 1 Completed

BreastGastrointestinal

Biliary Tract Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02129257 2017-10-24

AMALTHEA

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT01882868 2017-03-14

A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan

Phase 2 Completed

62 enrolled 34 charts

Gastrointestinal

Colorectal Cancer Metastatic

NCT01749956 2017-02-07

5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer

Phase 2 Completed

39 enrolled 13 charts

Gastrointestinal

Rectal Neoplasms

NCT01670721 2016-11-28

AFEQT

Phase 3 Completed

175 enrolled 6 charts

Gastrointestinal

Colorectal Cancer Metastatic

NCT01661270 2016-10-18

AFLAME

Phase 3 Completed

332 enrolled 9 charts

Gastrointestinal

Colorectal Cancer Metastatic

NCT00851084 2016-06-07

AFFIRM

Phase 2 Completed

268 enrolled 16 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT00082823 2016-06-03

Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Phase 1 Completed

GastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmSarcoma

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Burkitt Lymphoma, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Sarcoma, Testicular Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Endometrial Neoplasms, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00083213 2016-06-03

Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Phase 1 Completed

GastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmSarcoma

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Burkitt Lymphoma, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Sarcoma, Testicular Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Endometrial Neoplasms, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00921661 2012-11-09

Study of Intravenous Aflibercept in Combination With FOLFIRI in Japanese Patients With Metastatic Colorectal Cancer

Phase 1 Completed

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT00561470 2012-09-28

VELOUR

Phase 3 Completed

1,226 enrolled 16 charts

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms