Clinical Trials

28 enrolled

Colorectal Cancer, Hereditary Nonpolyposis, Type 6, Carcinoma, Colorectal Neoplasms

NCT07137390 2026-03-11

A Trial of Regorafenib Plus Lorigerlimab as Neoadjuvant Therapy for Patients With pMMR/MSS, Resectable, Lung-limited Metastatic Colorectal Cancer

Phase 1/2 Withdrawn

Colorectal Neoplasms

NCT07463599 2026-03-11

Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma

126 enrolled

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT04380545 2026-03-06

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

15 enrolled

Carcinoma, Hepatocellular

NCT06412198 2026-03-06

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

31 enrolled

EndocrineGastrointestinalThoracic

Colorectal Neoplasms

NCT04785287 2026-03-03

Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies

Phase 1/2 Terminated

13 enrolled

Adrenal Gland Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT03652428 2026-03-02

Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC)

Locally Advanced Pancreatic Cancer

NCT07277322 2026-03-02

Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases

Colorectal Neoplasms

NCT03828799 2026-02-27

FOLFIRINOX-R

13 enrolled 22 charts

Colorectal Neoplasms

NCT05639972 2026-02-27

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

GastrointestinalGenitourinaryGynecologicHead & Neck

15 enrolled

Anus Neoplasms, Uterine Cervical Neoplasms, Oropharyngeal Neoplasms, Penile Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms

NCT05664178 2026-02-27

Remote Resistance Exercise Powering Survivors - Gastrointestinal Oncology

100 enrolled

Gastrointestinal Neoplasms

NCT07435584 2026-02-27

EVER-RECODE

38 enrolled

Colorectal Neoplasms

NCT04605913 2026-02-25

Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC

40 enrolled

Adenocarcinoma, Pancreatic Neoplasms

NCT05642962 2026-02-25

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

17 enrolled

Pancreatic Neoplasms

NCT07433283 2026-02-25

Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor

GastrointestinalGynecologicHead & NeckThoracic

54 enrolled

Uterine Cervical Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms

NCT03942328 2026-02-24

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

85 enrolled

Carcinoma, Hepatocellular, Cholangiocarcinoma

NCT05419479 2026-02-24

Switch Maintenance in Pancreatic

Phase 1/2 Suspended

46 enrolled

Pancreatic Neoplasms

NCT05922930 2026-02-19

Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer

GastrointestinalGynecologic

51 enrolled

Adenocarcinoma, Ovarian Neoplasms, Pancreatic Neoplasms

NCT06608940 2026-02-19

BC3402 w/ Tremelimumab + Durvalumab (STRIDE) in Hepatocellular Carcinoma

Phase 1/2 Withdrawn

Liver Neoplasms

NCT07281716 2026-02-19

Combination Immunotherapy for the Treatment of Chemotherapy-refractory Metastatic MSS CRC

BreastEndocrineGastrointestinalGenitourinaryGynecologicNETSarcoma

Colorectal Neoplasms

NCT05000294 2026-02-18

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

Phase 1/2 Suspended

29 enrolled

Bile Duct Neoplasms, Breast Neoplasms, Gallbladder Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Vulvar Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors

NCT07410494 2026-02-18

SELECT-CAR-NK

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmPlasma cellThoracic

85 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Carcinoma, Hepatocellular, Liver Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Leukemia, Myeloid, Acute

NCT07410676 2026-02-18

EBNK-ST-001

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT07412197 2026-02-17

PREVENT-Lynch

23 enrolled

Colorectal Neoplasms, Hereditary Nonpolyposis

NCT03785873 2026-02-13

Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract Cancer

34 enrolled 13 charts

Biliary Tract Neoplasms

NCT06384560 2026-02-13

PREOPANC-5

66 enrolled

Localized Pancreatic Adenocarcinoma

NCT06027086 2026-02-12

DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

27 enrolled

Fibrolamellar hepatocellular carcinoma, Carcinoma

NCT03516708 2026-02-11

Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

49 enrolled

Rectal Neoplasms

NCT07353645 2026-02-10

KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer

49 enrolled

Pancreatic Neoplasms, Colorectal Neoplasms

NCT04901702 2026-02-09

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

CNSGastrointestinalGenitourinarySarcoma

90 enrolled

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT07214298 2026-02-06

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

35 enrolled

Pancreatic Neoplasms

NCT07392541 2026-02-06

Adebrelimab Combined With Gemcitabine, Cisplatin, and Simvastatin for Advanced Biliary Tract Cancer

29 enrolled

Advanced Biliary Tract Carcinoma

NCT00989469 2026-02-05

NEXIRI

64 enrolled

Colorectal Neoplasms

NCT03211416 2026-02-05

Sorafenib Tosylate and Pembrolizumab in Treating Patients With Advanced or Metastatic Liver Cancer

37 enrolled 13 charts

Carcinoma, Hepatocellular

NCT07385001 2026-02-03

A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC

45 enrolled

Esophageal Squamous Cell Carcinoma

NCT07377526 2026-01-30

Phase 1/2 Study TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic Cancer

37 enrolled

Pancreatic Neoplasms

NCT05672316 2026-01-28

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

28 enrolled

Colorectal Neoplasms

NCT03386500 2026-01-26

Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer

Anus Neoplasms

NCT07312422 2026-01-26

LDRT Combined With Pucotenlimab and Standard Therapy for Advanced Pancreatic Cancer: A Single-Arm Study

10 enrolled

Pancreatic Neoplasms

NCT07365592 2026-01-26

Neo-CD

138 enrolled

Colorectal Neoplasms

NCT04781192 2026-01-23

The Purpose of This Trial is to Determine if Regorafenib Plus Durvalumab (MEDI4736) is Safe and Effective in Treatment of Chemo Refractory Advanced Biliary Tract Cancers

40 enrolled