Clinical Trials

GastrointestinalGynecologic

442 enrolled

Fallopian Tube Neoplasms, Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies, Ovarian Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Carcinoma, Acinar Cell

NCT04678648 2026-03-18

A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies

CNSGastrointestinalThoracic

134 enrolled

Colonic Neoplasms, Glioblastoma, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Disease Progression

NCT05217446 2026-03-18

SEAMARK

Phase 2 Active not recruiting

107 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05359861 2026-03-18

Trial of Atezolizumab and Bevacizumab With SRF388 or Placebo in Patients With Hepatocellular Carcinoma

Phase 2 Completed

30 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasms

NCT05702229 2026-03-18

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

163 enrolled

Stomach Neoplasms

NCT05954312 2026-03-18

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

290 enrolled

Adenocarcinoma Of Esophagus, Neoplasms

NCT06244771 2026-03-18

PROSPER

403 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06324357 2026-03-18

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

768 enrolled

BreastGastrointestinal

Adenocarcinoma Of Esophagus, Breast Neoplasms, Colorectal Neoplasms

NCT06427941 2026-03-18

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

140 enrolled

Simpson-Golabi-Behmel syndrome, Carcinoma, Hepatocellular

NCT06585488 2026-03-18

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

GastrointestinalOther solid neoplasmThoracic

514 enrolled

Metastatic Solid Tumors

NCT06599502 2026-03-18

ALAFOSS-01

Phase 1 Terminated

17 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT06625775 2026-03-18

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

BreastGastrointestinalThoracic

392 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Colorectal Neoplasms

NCT06803927 2026-03-18

DETECT-ME

Recruiting

700 enrolled

Barrett Esophagus

NCT06917079 2026-03-18

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

387 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Colorectal Neoplasms

NCT07479381 2026-03-18

CLEAR

Not yet recruiting

1,450 enrolled

Phase 1/2 Not yet recruiting

Disease, Neoplasms, Colorectal Neoplasms

NCT07479485 2026-03-18

MRG006A Combination Therapy for Advanced Hepatocellular Carcinoma (Phase I/II)

160 enrolled

Carcinoma, Hepatocellular

NCT07480928 2026-03-18

DUAL-NK-PDAC

42 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT07481058 2026-03-18

A Study of KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy as First-line Treatment in Patients With Advanced Esophageal Cancer

60 enrolled

Phase 1 Not yet recruiting

Esophageal Squamous Cell Carcinoma

NCT07481357 2026-03-18

A First-In-Human Phase I/IIa Study to Evaluate DA 3501 in Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma and Pancreatic Ductal Adenocarcinoma

51 enrolled

Stomach Neoplasms

NCT07481383 2026-03-18

A First-in-Human Study to Evaluate Implantable Iontophoresis Chemotherapy Delivery Device With Gemcitabine Once Weekly or Twice Weekly in Participants With Pancreatic Cancer

12 enrolled

Pancreatic Neoplasms

NCT04486378 2026-03-17

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

327 enrolled

Phase 1 Active not recruiting

Neoplasms, Colorectal Neoplasms

NCT05846516 2026-03-17

A Study to Test KISIMA-02 Vaccine-based Immunotherapy and Ezabenlimab in People With Pancreatic Cancer

58 enrolled

Pancreatic Ductal Adenocarcinoma

NCT06157892 2026-03-17

A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors

172 enrolled

BreastGastrointestinal

Breast Neoplasms, Stomach Neoplasms, Triple Negative Breast Neoplasms

NCT06882746 2026-03-17

A Study to Test Different Doses of BI 765049 in People With Advanced Cancer of the Colon, Rectum, Stomach, or Pancreas

135 enrolled

Stomach Neoplasms, Colorectal Neoplasms

NCT06921928 2026-03-17

Study for AZD4360 in Participants With Advanced Solid Tumours

117 enrolled

Biliary Tract Neoplasms, Stomach Neoplasms

NCT06926075 2026-03-17

ADVICE

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicThoracic

80 enrolled

Breast Neoplasms, Glioblastoma, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Skin Neoplasms

NCT06950385 2026-03-17

SERENTA

Phase 3 Recruiting

168 enrolled

GastrointestinalGenitourinaryGynecologicThoracic

Adenomatous Polyposis Coli, Polyps

NCT06973161 2026-03-17

ESPERANZA: External Control Arm Study for T-DXd for Patients With HER2 IHC3+ Solid Tumors

Recruiting

105 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06992258 2026-03-17

FRUITION

120 enrolled

Colorectal Neoplasms

NCT07115043 2026-03-17

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors