Clinical Trials

40 enrolled

Carcinoma, Hepatocellular

NCT04238715 2026-03-02

A Study of E7090 in Participants With Unresectable Advanced or Metastatic Cholangiocarcinoma With Fibroblast Growth Factor Receptor (FGFR) 2 Gene Fusion

63 enrolled

Acrocephalosyndactylia, Cholangiocarcinoma

NCT06137170 2026-03-02

RegoSeq

121 enrolled

Colorectal Neoplasms

NCT04526106 2026-02-27

REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors

490 enrolled

Cholangiocarcinoma

NCT05304936 2026-02-27

HCW9218 for Advanced Pancreatic Cancer

21 enrolled

Advanced Pancreatic Carcinoma

NCT02705196 2026-02-24

LOAd703 Oncolytic Virus Therapy for Pancreatic Cancer

51 enrolled

Adenoviridae Infections, Neoplasms, Pancreatic Neoplasms

NCT04426669 2026-02-23

A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

23 enrolled

Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT03463876 2026-02-17

A Trial of SHR-1210 (an Anti-PD-1 Inhibitor) in Combination With Apatinib in Patients With Advanced HCC(RESCUE)

190 enrolled 15 charts

Carcinoma, Hepatocellular

NCT05116085 2026-02-13

Efficacy and Safety of Tislelizumab (BGB-A317) as Neo-Adjuvant Treatment in Participants With Colorectal Cancer

33 enrolled 11 charts

Colorectal Neoplasms

NCT06229080 2026-02-12

SEGWAY

Phase NA Completed

20 enrolled

Liver Neoplasms, Neoplasm Metastasis

NCT03362177 2026-02-11

RECITE

165 enrolled 22 charts

Gastrointestinal Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05381753 2026-02-11

Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World

61 enrolled

GastrointestinalSarcoma

Gastrointestinal Stromal Tumors

NCT04513223 2026-02-06

A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors

101 enrolled

Stomach Neoplasms, Colorectal Neoplasms

NCT03713593 2026-02-05

LEAP-002

794 enrolled 30 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Hepatocellular

NCT04776148 2026-02-05

MK-7902-017

563 enrolled 32 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Colorectal Neoplasms

NCT03867084 2026-02-04

KEYNOTE-937

959 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Hepatocellular

NCT05731947 2026-01-29

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

42 enrolled

Colorectal Neoplasms

NCT03798626 2026-01-27

Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers

GastrointestinalGenitourinary

167 enrolled

Carcinoma, Renal Cell, Colorectal Neoplasms

NCT04640480 2026-01-27

Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors

BreastGastrointestinalGynecologicHead & NeckThoracic

21 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Small Cell Lung Carcinoma

NCT05360680 2026-01-22

A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers

GastrointestinalGenitourinaryGynecologic

42 enrolled

Wilms Tumor, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05641896 2026-01-22

18F-FAPI-74 GI

109 enrolled

Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT03377491 2026-01-21

Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3)

571 enrolled 22 charts

Pancreas Adenocarcinoma

NCT05512377 2026-01-21

Brightline-2: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or Bladder

GastrointestinalGenitourinaryThoracic

99 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Lung Neoplasms, Pancreatic Neoplasms

NCT03834272 2026-01-16

Feasibility of the LUM Imaging System for Peritoneal Surface Malignancies

GastrointestinalGynecologicOther solid neoplasmThoracic

18 enrolled

Gastrointestinal Neoplasms, Mesothelioma, Ovarian Neoplasms, Peritoneal Neoplasms

NCT04744831 2026-01-14

DESTINY-CRC02

122 enrolled 21 charts 1 FDA

Colorectal Neoplasms

NCT04889404 2026-01-14

LYNPARZA Pancreas Cancer Japan Post-Marketing Surveillance (PMS)

130 enrolled

Pancreatic Neoplasms

NCT05835778 2026-01-14

Imfinzi BTC Japan PMS_Japan Post-Marketing Surveillance (PMS) Study - CEI/SCEI

236 enrolled

Biliary Tract Neoplasms

NCT05628857 2026-01-06

A Study of RC108-ADC in Subjects With Advanced Digestive System Malignant Tumor

29 enrolled

Gastrointestinal Neoplasms

NCT04317599 2026-01-02

CAPSTAN CRC

274 enrolled 39 charts

Colorectal Neoplasms

NCT04045496 2025-12-29

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors

BreastGastrointestinalHead & NeckThoracic

40 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Noonan Syndrome, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT04369053 2025-12-26

PREEMPT CRC

48,995 enrolled 15 charts

Adenoma, Colonic Diseases, Colonic Neoplasms, Colonic Polyps, Gastrointestinal Neoplasms, Polyps, Rectal Diseases, Rectal Neoplasms, Colorectal Neoplasms

NCT01658878 2025-12-24

CheckMate040

657 enrolled 57 charts 3 FDA

Carcinoma, Hepatocellular

NCT05846594 2025-12-17

L1st

Phase NA Completed

463 enrolled

GastrointestinalThoracic

Gastrointestinal Neoplasms, Lung Neoplasms

NCT05001347 2025-12-16

A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors

BreastGastrointestinalGynecologicHead & NeckThoracic

25 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT05419362 2025-12-16

GEN-001 in Combination With Avelumab for Patients With PD-L1 Positive Gastric Cancer

42 enrolled

Stomach Neoplasms

NCT03281369 2025-12-15

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

214 enrolled

Esophageal Neoplasms

NCT06549816 2025-12-15

A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors