Clinical Trials

DermatologicGastrointestinalGenitourinaryThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Colorectal Neoplasms

NCT04792463 2026-03-09

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

500 enrolled

Uveal Melanoma, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Cholangiocarcinoma

NCT07124000 2026-02-24

DP-04

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

100 enrolled

Adenocarcinoma, Anus Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Melanoma, Mouth Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms, Gastrointestinal Stromal Tumors, Small Cell Lung Carcinoma

NCT04354064 2026-02-20

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

100 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT05863052 2026-02-10

Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population

Active not recruiting

72 enrolled

DermatologicGastrointestinalGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Gastrointestinal Neoplasms, Melanoma, Neoplasm Metastasis

NCT05334069 2026-02-04

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

BreastDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidOther hematologic neoplasmSarcomaThoracic

2,000 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Esophageal Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02012699 2026-01-22

iCaRe2

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

999,999 enrolled

Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Colonic Neoplasms, Colorectal Neoplasms, Hereditary Nonpolyposis, Duodenal Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Hypopharyngeal Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Lip Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Multiple Myeloma, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Paranasal Sinus Neoplasms, Paraproteinemias, Penile Neoplasms, Peritoneal Neoplasms, Adenomatous Polyposis Coli, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Ureteral Neoplasms, Urethral Neoplasms, Vaginal Neoplasms, Central Nervous System Neoplasms, Thyroid Nodule, Endometrial Neoplasms, Neuroendocrine Tumors, Gastrointestinal Stromal Tumors

NCT07327489 2026-01-08

ELEPHAS-05

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

2,000 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Melanoma, Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05520099 2025-12-26

ELEPHAS-02

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

416 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07246759 2025-11-24

NEUTROFLOW

Not yet recruiting

600 enrolled

BreastDermatologicGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Triple Negative Breast Neoplasms

NCT03728842 2025-10-27

Spontaneous Regression in Metastatic Melanoma and Renal Cell Carcinoma

Active not recruiting

19 enrolled

Carcinoma, Renal Cell, Melanoma, Neoplasm Metastasis, Remission, Spontaneous

NCT05461430 2025-09-15

TraveraRTGx

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

200 enrolled

Anus Neoplasms, Appendiceal Neoplasms, Ascites, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Stomach Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Small Cell, Carcinoma, Pancreatic Ductal, Gastrointestinal Stromal Tumors

NCT01777802 2025-08-27

SBRT

BreastDermatologicGenitourinaryThoracic

98 enrolled

Breast Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms

NCT05059444 2025-08-22

ORACLE

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

2,020 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Melanoma, Rectal Neoplasms, Ureteral Neoplasms, Endometrial Neoplasms

NCT05621837 2025-05-02

Serpentine

BreastDermatologicGenitourinaryHead & Neck

1,000 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Melanoma, Carcinoma, Small Cell

NCT06043947 2025-05-01

SURVIMON

Active not recruiting

100,000 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms

NCT05819827 2025-04-27

Associations Between Chemotherapy-Induced Nausea in Patients With Genitourinary, Sarcoma or Melanoma Cancers and Changes in Gut Microbiome: Potential for Precision Therapeutics

DermatologicGenitourinarySarcoma

13 enrolled

Urinary Bladder Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Testicular Neoplasms

NCT00026754 2025-04-18

Eligibility Screening for the NIH Intramural Research Program Clinical Protocols

BreastDermatologicGenitourinarySarcomaThoracic

19,522 enrolled

Breast Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms, Sarcoma, Skin Diseases, HIV Infections

NCT05697198 2025-03-06

PREFER

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

1,429 enrolled

Breast Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT05231655 2025-02-24

EVIDENT

CNSDermatologicGenitourinaryHead & NeckSarcoma

600 enrolled

Urinary Bladder Neoplasms, Glioblastoma, Head and Neck Neoplasms, Kidney Neoplasms, Melanoma, Sarcoma

NCT05403177 2025-02-03

MOHCCN-O

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmThoracic

500 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT05878964 2024-10-04

SkinHealth

BreastDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

420 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Melanoma, Skin Neoplasms, Stomach Neoplasms

NCT00341939 2024-06-13

Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data

BreastDermatologicGenitourinaryLymphoidThoracic

484 enrolled

Breast Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Prostatic Neoplasms, Lymphoma, T-Cell, Cutaneous

NCT02333604 2024-04-15

CER

BreastDermatologicGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

15,000 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute

NCT06321640 2024-03-20

POSITive

BreastDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

265 enrolled

Breast Neoplasms, Carcinoma, Transitional Cell, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT03709771 2024-01-12

Novel Mechanisms and Predictors of VEGF Receptor Inhibitor- or Immune Checkpoint Inhibitor-Associated Hypertension and Cardiovascular Disease

2 enrolled 6 charts

Carcinoma, Renal Cell, Hypertension, Melanoma, Neoplasms

NCT00617799 2023-10-10

Biomarkers That Predict Response to High-Dose Aldesleukin in Metastatic Kidney Cancer or Metastatic Melanoma

15 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms, Melanoma

NCT05223218 2023-07-03

Investigating the Diagnostic Potential of Tear Proteins in Cancer - A Pilot Study

BreastDermatologicGastrointestinalGenitourinaryGynecologic

500 enrolled

Breast Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms

NCT00001503 2023-06-18

Follow-up Protocol for Patients With Cancer/AIDS/Skin Disease

BreastDermatologicGenitourinaryGynecologicLymphoid

1,031 enrolled

Breast Neoplasms, Lymphoma, Melanoma, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms

NCT04960059 2023-04-12

NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts

DermatologicGenitourinaryThoracic

30 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms

NCT04107168 2023-02-16

Microbiome Immunotherapy Toxicity and Response Evaluation

DermatologicGenitourinaryThoracic

1,800 enrolled

Kidney Neoplasms, Lung Neoplasms, Melanoma

NCT05380336 2022-06-01

IMEPOCA

40,000 enrolled

Kidney Neoplasms, Melanoma, Neoplasm Metastasis

NCT05037825 2022-04-27

PARADIGM

BreastDermatologicGenitourinaryThoracic

800 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Triple Negative Breast Neoplasms

NCT05230186 2022-02-09

A Tissue Collection Study in Patients Who Respond to Immune Checkpoint Inhibitors to Identify Targets of Tumor-Reactive T Cells.

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

200 enrolled

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Lung Neoplasms, Melanoma, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04628806 2021-05-14

HSP70CTC

BreastDermatologicGastrointestinalGenitourinarySarcoma

120 enrolled

Breast Neoplasms, Carcinoma, Squamous Cell, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma

NCT03896958 2020-12-04

PIONEER

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

1,000 enrolled

Adenocarcinoma of Lung, Adrenal Gland Neoplasms, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms, Unknown Primary, Neurologic Manifestations, Oligodendroglioma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Uterine Neoplasms, Vulvar Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Thyroid Carcinoma, Anaplastic

NCT04268368 2020-02-17

ICI-DISCOVER

DermatologicGenitourinaryThoracic

200 enrolled

Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Neoplasms

NCT01415167 2019-06-13

PROCLAIM Registry to Evaluate the Treatment Patterns and Clinical Response in Malignancy

1,690 enrolled

Carcinoma, Renal Cell, Melanoma

NCT00477919 2019-05-15

E-MOSAIC Electronic Tool to Monitor Symptoms

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther solid neoplasmSarcomaThoracic

264 enrolled

Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Anorexia, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Body Weight Changes, Brain Neoplasms, Breast Neoplasms, Cachexia, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Depression, Esophageal Neoplasms, Fatigue, Gallbladder Neoplasms, Glioblastoma, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pain, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Stomach Neoplasms, Gliosarcoma, Breast Neoplasms, Male, Small Cell Lung Carcinoma

NCT02900248 2019-04-02

N1

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellSarcomaThoracic

23 enrolled

Anus Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Endometrial Neoplasms, Hematologic Neoplasms

NCT03517332 2018-11-20

Circulating Tumor DNA Exposure in Peripheral Blood

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

10,000 enrolled

Adrenal Cortex Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT01528774 2017-07-26

CTC

DermatologicGenitourinarySarcoma

150 enrolled

Kidney Neoplasms, Melanoma, Neoplastic Cells, Circulating, Prostatic Neoplasms, Sarcoma, Somatostatinoma

NCT00899496 2017-05-30

Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants

BreastDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmPlasma cellSarcomaThoracic

54 enrolled

Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Immunoblastic Lymphadenopathy, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Melanoma, Multiple Myeloma, Mycosis Fungoides, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Sezary Syndrome, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Intraocular Lymphoma

NCT00900302 2016-02-10

OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

98 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Penile Neoplasms, Salivary Gland Neoplasms, Skin Neoplasms, Vulvar Neoplasms, Breast Neoplasms, Male

NCT01068470 2014-05-29

LAK

11 enrolled

Kidney Neoplasms, Melanoma

NCT00757614 2013-08-26

Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the United Kingdom