Clinical Trials

256 enrolled

Wilms Tumor

NCT02861573 2026-02-17

KEYNOTE-365

Phase 1/2 Recruiting

1,200 enrolled

Phase 2 Active not recruiting

Metastatic Castration-Resistant Prostate Cancer

NCT03937843 2026-01-20

Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma

135 enrolled

Testicular Neoplasms, Seminoma

NCT06039371 2026-01-14

Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study

69 enrolled

Prostatic Neoplasms

NCT06091124 2025-12-08

NEOBLAST

22 enrolled

Phase 1 Active not recruiting

Urinary Bladder Neoplasms

NCT03582475 2025-11-12

Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate

15 enrolled 17 charts

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Prostatic Neoplasms, Urethral Neoplasms

NCT05312671 2025-06-29

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

63 enrolled

Urinary Bladder Neoplasms

NCT00936936 2024-08-26

High-dose Chemotherapy for Poor-Prognosis Relapsed Germ-Cell Tumors

64 enrolled 10 charts

Testicular Neoplasms

NCT06309732 2024-03-13

GAMEC-II

36 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT01505569 2024-02-26

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Phase NA Completed

44 enrolled

Brain Neoplasms, Carcinoma, Renal Cell, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Rhabdoid Tumor

NCT00483561 2023-09-13

Gefitinib and Etoposide in Treating Patients With Advanced Prostate Cancer That Did Not Respond to Hormone Therapy

Phase 2 Terminated

26 enrolled 7 charts

Prostatic Neoplasms

NCT00432094 2022-05-17

Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors

23 enrolled 11 charts

Ovarian Germ Cell Cancer, Ovarian Neoplasms, Teratoma, Testicular Neoplasms, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor

NCT00053352 2021-07-13

Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors

302 enrolled 9 charts

Ovarian Germ Cell Cancer, Teratoma, Testicular Neoplasms, Endodermal Sinus Tumor

NCT00002566 2021-02-23

Combination Chemotherapy With Bone Marrow Transplantation in Treating Men With Germ Cell Tumors

280 enrolled

Testicular Germ Cell Tumor, Testicular Neoplasms

NCT00004054 2020-10-22

Hormone Therapy Plus Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Prostate Cancer

397 enrolled 11 charts

Prostatic Neoplasms

NCT00514540 2020-09-01

Carboplatin Plus Docetaxel (Taxotere) in Anaplastic Prostate Cancer

121 enrolled 8 charts

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Prostatic Neoplasms

NCT00007813 2020-02-17

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors

Phase 1 Completed

21 enrolled

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00960063 2018-08-27

A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006)

Phase 1 Terminated

4 enrolled 8 charts

CNSGenitourinarySarcoma

Bone Neoplasms, Carcinoma, Renal Cell, Neoplasms, Neuroblastoma

NCT00002943 2018-08-10

Carboplatin, Etoposide, Cyclophosphamide, and Autologous Bone Marrow Transplantation in Patients With Relapsed or Refractory Cancer

11 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Testicular Germ Cell Tumor, Ovarian Neoplasms, Testicular Neoplasms

NCT00623077 2017-12-05

MT2004-30: Tomotherapy for Solid Tumors

Phase 1 Terminated

23 enrolled

Familial ependymoma, Astrocytoma, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00335556 2017-07-21

Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

291 enrolled 18 charts

Carcinoma, Renal Cell, Wilms Tumor

NCT00002931 2017-02-23

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer

CNSGenitourinaryGynecologic

48 enrolled 7 charts

Testicular Germ Cell Tumor, Ovarian Neoplasms, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor

NCT00003657 2017-01-20

High-dose ICE With Amifostine

CNSGenitourinaryGynecologicHead & NeckSarcomaThoracic

24 enrolled

AIDS-related Kaposi sarcoma, Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Chondrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Ovarian Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT00003852 2016-06-23

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors

Phase 2 Terminated

45 enrolled

Testicular Germ Cell Tumor, Ovarian Neoplasms, Testicular Neoplasms

NCT00002558 2016-05-23

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Germ Cell Tumors

Phase 1/2 Completed

108 enrolled 7 charts

Testicular Germ Cell Tumor, Ovarian Neoplasms, Testicular Neoplasms

NCT01084759 2016-05-09

A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer

Phase NA Completed

16 enrolled 12 charts

BreastDermatologicGenitourinaryThoracic

Prostatic Neoplasms

NCT00006126 2015-11-13

Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell Lung, Breast, Testicular, or Kidney Cancer That is Metastatic or That Cannot Be Treated With Surgery

Phase 1 Withdrawn

Testicular Germ Cell Tumor, Breast Neoplasms, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Testicular Neoplasms, Small Cell Lung Carcinoma

NCT00002854 2015-08-26

High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer

Phase 1 Completed

33 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcoma

Carcinoma, Ovarian Epithelial, Anus Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Wilms Tumor, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Stomach Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

NCT02208583 2014-08-05

Molecular Phenotype Changes and Personalized Treatment for CRPC

Phase NA Unknown

150 enrolled

Hormone Refractory Prostate Cancer

NCT00002610 2014-07-25

Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors

203 enrolled

CNSClassical hematologyDermatologicGenitourinaryGynecologicOther solid neoplasmSarcoma

Kidney Neoplasms, Wilms Tumor

NCT00003597 2014-07-24

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Phase 1 Completed

16 enrolled

Uveal Melanoma, Astrocytoma, Carcinoma, Renal Cell, Medulloblastoma, Melanoma, Neoplasms, Wilms Tumor, Neuroblastoma, Neutropenia, Retinoblastoma, Osteosarcoma, Testicular Neoplasms, Thrombocytopenia, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Gestational Trophoblastic Disease

NCT00047138 2014-06-24

Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor

Phase 3 Unknown

350 enrolled

Kidney Neoplasms, Wilms Tumor

NCT02161692 2014-06-12

Conventional Dose Versus High Dose Sequential Chemotherapy for Poor Prognosis Germ Cell Tumors

Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms

NCT00176605 2014-05-20

Phase II Metronomic Dosing, Etoposide, Cyclophosphamide, D0 Prostate Cancer

15 enrolled 7 charts

Prostatic Neoplasms

NCT00274950 2013-09-17

Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors

Phase 3 Unknown

105 enrolled

CNSGenitourinaryGynecologic

Ovarian Germ Cell Cancer, Ovarian Neoplasms, Teratoma, Testicular Neoplasms

NCT00276718 2013-09-17

Etoposide, Carboplatin, and Bleomycin in Treating Young Patients Undergoing Surgery For Malignant Germ Cell Tumors

Phase NA Unknown

100 enrolled

Ovarian Germ Cell Cancer, Ovarian Neoplasms, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms

NCT00324298 2013-08-12

Bleomycin, Etoposide, and Cisplatin in Treating Patients With Metastatic Germ Cell Cancer of the Testicles

210 enrolled

Testicular Germ Cell Tumor, Testicular Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00025103 2013-08-02

Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney

Phase 2 Unknown

75 enrolled

Kidney Neoplasms, Wilms Tumor

NCT00028769 2013-07-16

S0032, Combination Chemotherapy Plus Hormone Therapy in Treating Patients With Metastatic Prostate Cancer

41 enrolled 12 charts

Prostatic Neoplasms

NCT00002596 2013-06-26

Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors

270 enrolled

Teratoma, Testicular, Testicular Germ Cell Tumor, Teratoma, Testicular Neoplasms, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor

NCT00002466 2013-06-20

Combination Chemotherapy and Radiation Therapy in Treating Patients With Peripheral Neuroectodermal Tumors, Ewing's Sarcoma, Wilms' Tumor, or Bone Cancer

GenitourinarySarcoma

Askin Tumor, Kidney Neoplasms, Wilms Tumor, Sarcoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT00060255 2013-05-09

High-Dose Chemotherapy, Total-Body Irradiation, and Autologous Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Hematologic Cancer or Solid Tumors

BreastGenitourinaryLymphoidOther hematologic neoplasmPlasma cellSarcoma

451 enrolled

Testicular Germ Cell Tumor, Congenital Abnormalities, Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Recurrence, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Breast Neoplasms, Male, Lymphoma, Mantle-Cell, Neoplasms, Plasma Cell, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating

NCT01604863 2012-11-01

A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid Malignancies

Phase 1 Suspended

54 enrolled

GenitourinaryOther solid neoplasmThoracic

Lung Neoplasms, Mesothelioma, Neoplasms, Prostatic Neoplasms, Small Cell Lung Carcinoma

NCT00003941 2012-09-24

Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer

222 enrolled

CNSGenitourinary

Teratoma, Testicular, Testicular Germ Cell Tumor, Brain Neoplasms, Mediastinal Neoplasms, Neoplasm Metastasis, Teratoma, Testicular Neoplasms, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor

NCT00003084 2012-07-30

Combination Chemotherapy With Ketoconazole in Treating Patients With Prostate Cancer

75 enrolled

Prostatic Neoplasms

NCT00973882 2011-11-03

Carboplatin-Etoposide Combination in Hormone-Resistant Prostate Cancers

60 enrolled

Prostatic Neoplasms

NCT00627354 2011-05-16

Mitoxantrone, Etoposide, and Vinorelbine As Second-Line Therapy in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy

90 enrolled

Prostatic Neoplasms

NCT00231582 2011-02-25

High-dose Chemotherapy With Autologous Stem Cell Transplantation in Poor Prognosis Germ-cell Tumors: TAXIF II

50 enrolled