Clinical Trials

475 enrolled

Urinary Bladder Neoplasms

NCT06770582 2026-03-18

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Phase 2 Recruiting

160 enrolled

Urinary Bladder Neoplasms

NCT06211764 2026-03-17

SunRISe-5

272 enrolled

Non-Muscle Invasive Bladder Neoplasms

NCT06919965 2026-03-13

MoonRISe-3

220 enrolled

Non-Muscle Invasive Bladder Neoplasms

NCT03348969 2026-03-03

NICSA

Phase 4 Completed

120 enrolled

Urinary Bladder Neoplasms

NCT04172675 2026-02-24

A Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Participants Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC)

107 enrolled 17 charts

Phase 3 Not yet recruiting

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT07424287 2026-02-20

A Study of Intravesical SHR-1501 Combination With BCG Versus Investigator-selected Chemotherapy in Subjects With BCG-unresponsive NMIBC

236 enrolled

Non-Muscle Invasive Bladder Neoplasms

NCT07097142 2026-02-02

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

486 enrolled

Urinary Bladder Neoplasms

NCT06774131 2026-01-16

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

70 enrolled

Carcinoma, Transitional Cell

NCT06331299 2026-01-15

UTOPIA

99 enrolled

Phase 2 Active not recruiting

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT04216290 2025-11-12

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

95 enrolled

Urinary Bladder Neoplasms

NCT06781879 2025-10-03

COBRA-NMIBC

Phase 4 Recruiting

272 enrolled

Phase 2 Not yet recruiting

Non-Muscle Invasive Bladder Neoplasms, Recurrence

NCT07189793 2025-09-24

OHAI-NMIBC-01

106 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Carcinoma in Situ, Carcinoma, Transitional Cell

NCT06704191 2025-09-22

In-home Intravesical Chemotherapy for the Treatment of Bladder Cancer, INVITE Trial

Phase 1/2 Recruiting

40 enrolled

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT06388720 2025-09-15

IMGeS

Phase 2 Recruiting

82 enrolled

Urinary Bladder Neoplasms

NCT02106572 2025-07-23

TIM

548 enrolled

Non-Muscle Invasive Bladder Neoplasms

NCT05024734 2025-03-11

GAIN INST

Phase 2 Recruiting

34 enrolled

Urinary Bladder Neoplasms

NCT06696794 2025-02-19

Investigating the Efficacy and Safety of Neoadjuvant Intravesical Instillation of Mitomycin C in Treating High-risk NMIBC Patients

180 enrolled

Non-Muscle Invasive Bladder Neoplasms

NCT04241185 2024-11-25

MK-3475-992

520 enrolled

Urinary Bladder Neoplasms

NCT03658304 2024-11-05

Trial of Mitomycin C During Nephroureterectomy for Urothelial Carcinoma

29 enrolled 11 charts

Carcinoma, Transitional Cell

NCT05243550 2024-11-04

ENVISION

240 enrolled 20 charts 1 FDA

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT00981656 2024-09-19

Radiation Therapy and Chemotherapy in Treating Patients With Stage I Bladder Cancer

37 enrolled 19 charts

Urinary Bladder Neoplasms

NCT05136898 2024-09-19

Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC)

8 enrolled 18 charts

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT06462001 2024-06-17

BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder Cancer

500 enrolled

Carcinoma, Transitional Cell

NCT04688931 2024-06-06

ATLAS

282 enrolled 29 charts

Phase 2 Not yet recruiting

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT06227065 2024-01-26

POLO

28 enrolled

Phase 1 Not yet recruiting

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT05979909 2023-08-07

Intravesical Mitomycin C After Diagnostic Ureteroscopy for Upper Tract Urothelial Carcinoma

40 enrolled

Urothelial Carcinoma Ureter

NCT02948543 2023-06-18

BCG+MM

Phase 3 Unknown

501 enrolled

Urinary Bladder Neoplasms

NCT02695771 2023-04-21

BIC

101 enrolled 11 charts

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT03617913 2023-01-06

Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer

2 enrolled 8 charts

Urinary Bladder Neoplasms, Ureteral Neoplasms, Urethral Neoplasms

NCT03844256 2022-08-12

CRIMI

Phase 1/2 Recruiting

50 enrolled

Urinary Bladder Neoplasms

NCT02316171 2022-07-27

CANON

Phase 1 Completed

16 enrolled 8 charts

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT00318643 2021-10-29

Safety Study of Recombinant Human Hyaluronidase (Chemophase) in Combination With Mitomycin in Participants With Superficial Bladder Cancer

Phase 1/2 Completed

27 enrolled 14 charts

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT01438112 2021-04-14

BOND

Phase 2/3 Terminated

22 enrolled

Adenoviridae Infections, Urinary Bladder Neoplasms, Carcinoma in Situ, Carcinoma, Transitional Cell, Neoplasms, Virus Diseases

NCT02793128 2020-12-22

Olympus

71 enrolled 16 charts 2 FDA

Carcinoma, Carcinoma, Transitional Cell

NCT04006691 2020-05-07

Retreatment

Phase 3 Withdrawn

Carcinoma, Carcinoma, Transitional Cell

NCT03335059 2020-04-15

RITE-USA

5 enrolled

Urinary Bladder Neoplasms, Disease

NCT02982395 2019-08-30

Study to Evaluate the Efficacy and Safety Of Intravesical Nanoxel®M In BCG Refractory NMIBC

36 enrolled

Non-Muscle Invasive Bladder Neoplasms, Carcinoma, Transitional Cell

NCT03694535 2018-10-03

Intravesical Thermochemotherapy With Mitomycin-c

Phase NA Completed

44 enrolled

Urinary Bladder Neoplasms, Neoplasms

NCT00974818 2015-11-20

Mitomycin C Versus Bacillus Calmette-Guerin in the Intravesical Treatment of Non-Muscle-Invasive Bladder Cancer Patients

50 enrolled 7 charts

Phase EARLY_PHASE1 Completed

Urinary Bladder Neoplasms

NCT00734994 2015-06-29

Mitomycin C With Hyperthermia and Intravesical Mitomycin C to Treat Recurrent Bladder Cancer

15 enrolled 5 charts

Non-Muscle Invasive Bladder Neoplasms

NCT00024349 2013-12-18

Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer

350 enrolled

Urinary Bladder Neoplasms

NCT01094964 2013-08-12

Hyperthermia and Mitomycin C, Bacillus Calmette-Guerin, or Standard Therapy as Second-Line Therapy in Treating Patients With Recurrent Bladder Cancer

Phase 3 Unknown

242 enrolled

Urinary Bladder Neoplasms

NCT01920269 2013-08-09

EMDA/MMC

Phase 2/3 Completed

331 enrolled

Non-Muscle Invasive Bladder Neoplasms

NCT00023842 2012-09-24

BCG With or Without Mitomycin in Treating Patients With Bladder Cancer

97 enrolled

Urinary Bladder Neoplasms

NCT00042887 2012-09-24

Chemotherapy With or Without Surgery in Treating Patients With Bladder Cancer

58 enrolled

Urinary Bladder Neoplasms

NCT01149174 2011-10-04

EMDA/PRE-TUR

352 enrolled

Non-Muscle Invasive Bladder Neoplasms

NCT01442519 2011-09-28

BCG/EMDA-MMC

212 enrolled