Clinical Trials Browser

OTHER × Topotecan × Gynecologic × Clear all

NCT02569957 2025-05-04

Effect of Acetylcysteine With Topotecan Hydrochloride on the Tumor Microenvironment in Patients With Persistent or Recurrent High Grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2 Terminated

1 enrolled 5 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02312245 2024-12-05

Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2 Completed

13 enrolled 14 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00170625 2024-11-12

Therapy With Topotecan and Carboplatin by Patients With Relapsed Ovarian Cancer

Phase 1/2 Completed

28 enrolled 9 charts

Ovarian Neoplasms

NCT06548763 2024-08-12

Oral Topotecan With Toripalimab for Patients With Endometrial Cancer

Phase 2 Not yet recruiting

Endometrial Neoplasms

NCT02649673 2023-12-05

LCL161 Plus Topotecan for Patients With Relapsed/Refractory Small Cell Lung Cancer and Select Gynecologic Malignancies

Phase 1 Terminated

GynecologicThoracic

Lung Neoplasms, Ovarian Neoplasms, Small Cell Lung Carcinoma

NCT00317772 2022-02-07

Topotecan and Gefitinib (Iressa) for Ovarian, Peritoneal, or Fallopian Tube Cancer

Phase 1/2 Completed

19 enrolled 12 charts

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms, Peritoneal Neoplasms

NCT04679064 2021-08-27

NItCHE-MITO33

Phase 3 Unknown

Ovarian Neoplasms

NCT02903004 2021-08-25

MITO23

Phase 3 Completed

Ovarian Neoplasms

NCT02822157 2021-01-29

CLIO

Phase 2 Unknown

Carcinoma, Ovarian Epithelial

NCT00652691 2019-04-08

Topotecan, High-Dose Cyclophosphamide, Carboplatin, and an Autologous Peripheral Blood Cell Transplant in Treating Patients With Recurrent Ovarian Cancer or Primary Peritoneal Cancer

Phase 1 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT03367182 2019-01-11

REBECA

Ovarian Neoplasms

NCT00257816 2018-02-05

Weekly IV Topotecan and Cisplatin With Radiation in Cervical Carcinoma

Phase 2 Completed

Uterine Cervical Neoplasms

NCT00720096 2018-01-02

Genomic Directed Salvage Chemotherapy With Either Liposomal Doxorubicin Or Topotecan

Phase NA Terminated

4 enrolled 8 charts

Ovarian Neoplasms

NCT00287911 2017-12-02

Topotecan, Cisplatin, and Radiation Therapy in Treating Patients With Advanced Cervical Cancer

Phase 1 Completed

Uterine Cervical Neoplasms

NCT00287859 2017-11-29

Topotecan in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

Phase 1 Terminated

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00314678 2016-12-08

Cisplatin Induction With Paclitaxel Consolidation for Stage III-IV Epithelial Ovarian and Primary Peritoneal Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial

NCT00437307 2016-09-22

HECTOR

Phase 3 Completed

Ovarian Neoplasms

NCT02348398 2016-08-16

Phase II Study of Pazopanib and Topotecan in Cervical Cancer

Phase 2 Withdrawn

Uterine Cervical Neoplasms

NCT01003938 2016-06-30

Topotecan With Erlotinib for Topotecan Pretreated Ovarian Cancer

Phase 2 Terminated

6 enrolled 7 charts

Ovarian Neoplasms

NCT00045175 2016-06-23

UCN-01 and Topotecan in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer

Phase 1 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00526799 2016-03-03

Sorafenib + Topotecan for Platinum-Resistant Recurrent Ovarian Cancer

Phase 1/2 Terminated

30 enrolled 16 charts

Ovarian Neoplasms

NCT00006454 2015-12-23

Paclitaxel Plus Carboplatin With or Without Topotecan in Treating Patients With Stage IIB, Stage III, or Stage IV Ovarian Epithelial Cancer

Phase 3 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00072267 2015-07-23

UCN-01 and Topotecan in Treating Patients With Recurrent, Persistent, or Progressive Advanced Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01690598 2015-06-10

Veliparib and Topotecan for Relapsed Ovarian Cancer With Negative or Unknown BRCA Status

Phase 1/2 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00343044 2015-05-15

Ph II Study of Wkly Topotecan + Bevacizumab in Plat. Resistant/Recurrent Gyn Cancers

Phase 2 Completed

40 enrolled 10 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00550784 2014-10-07

Combination Chemotherapy and Autologous Peripheral Stem Cell Transplant in Treating Patients With Stage III, Stage IV, or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Phase 1 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00548418 2014-08-01

Topotecan, Cisplatin and Bevacizumab for Recurrent/Persistent Cervical Cancer

Phase 2 Completed

27 enrolled 14 charts

Uterine Cervical Neoplasms

NCT00170677 2014-05-14

Topotecan Weekly Versus Topotecan Day 1-5 in Patient With Platin-resistant Ovarian Cancer

Phase 2 Completed

Ovarian Neoplasms

NCT00436644 2014-04-16

Lapatinib and Topotecan in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Did Not Respond to Cisplatin or Carboplatin

Phase 2 Completed

18 enrolled 10 charts

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00703807 2014-01-14

Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial Cancers

Phase 1 Completed

Endometrial Neoplasms

NCT00523432 2013-09-05

A Phase I Study of CCI-779 (Temsirolimus) in Combination With Topotecan in Patients With Gynecologic Malignancies

Phase 1 Completed

Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Genital Neoplasms, Female, Ovarian Neoplasms, Uterine Neoplasms, Vaginal Neoplasms, Endometrial Neoplasms

NCT00842452 2013-04-05

Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery

Phase 1 Completed

GynecologicSarcoma

Carcinoma, Ovarian Epithelial, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Sarcoma, Vaginal Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT01177501 2012-11-19

ITOV04

Phase 1 Terminated

Ovarian Neoplasms, Recurrence

NCT00005051 2012-11-09

Combination Chemotherapy in Treating Patients With Advanced Ovarian Epithelial Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00005612 2012-09-26

ETC

Phase 1/2 Terminated

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00231855 2012-04-24

Efficacy Study of Weekly Taxotere and Topotecan for Recurrent Gynecologic (GYN) Cancers

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Recurrence, Uterine Neoplasms

NCT00250094 2011-09-07

Clinical Benefit of Topoisomerase Downregulation

Phase 1 Completed

Neoplasms, Ovarian Neoplasms

NCT00429559 2011-07-22

Topotecan in Combination With Gemcitabine in Patients With Platinum-resistant Ovarian Carcinoma

Phase 1/2 Completed

Neoplasms, Ovarian Neoplasms

NCT00193297 2011-05-03

Topotecan Plus Paclitaxel and Carboplatin in the Initial Treatment of Advanced Ovarian and Primary Peritoneal Carcinoma

Phase 2 Completed

Ovarian Neoplasms

NCT00006391 2011-04-05

Oxaliplatin and Topotecan in Treating Patients With Previously Treated Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

Phase 1 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00003297 2011-03-24

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Ovarian Cancer

Phase 1/2 Completed

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00189566 2011-02-25

Taxol® in Monotherapy or in Combination With Topotecan or Carboplatin in Patients With Epithelial Ovarian Cancer in Early Relapse

Phase 2 Completed

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00217555 2010-09-21

Gemcitabine and Topotecan in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00320983 2010-01-07

Study of Adjuvant Topotecan and Cisplatin With Concurrent Radiation Therapy for Advanced Cervical Cancer

Phase 1 Completed

Uterine Cervical Neoplasms, Neoplasms

NCT00315861 2009-01-23

Topotecan in Combination With Pemetrexed in Patients With Advanced Malignancies

Phase 1 Completed

GynecologicThoracic

Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Endometrial Neoplasms

NCT00826891 2009-01-22

Study of Cisplatin in Cervical Cancer Stage IVB

Phase 2 Unknown

Uterine Cervical Neoplasms

NCT00322920 2008-02-15

Efficacy Study of Weekly Topotecan With Cisplatin in Advanced Stage or Recurrent Cervical Cancer

Phase 1 Terminated

Uterine Cervical Neoplasms

NCT00194935 2006-09-13

Weekly Topotecan Therapy in Patients With Ovarian Cancer

Phase 2 Terminated

Ovarian Neoplasms

NCT00102375 2006-08-04

Paclitaxel, Carboplatin, and Topotecan in Patients With Ovarian Cancer

Phase 3 Completed

Ovarian Neoplasms

NCT00312988 2006-04-11

Topotecan Vs. Topotecan + Etoposide Vs.Topotecan + Gemcitabine in Ovarian Cancer Therapy

Phase 3 Completed

Ovarian Neoplasms