Clinical Trials

BreastGynecologicHead & NeckThoracic

41 enrolled 6 charts

Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Pelvic Neoplasms

NCT05169437 2025-10-29

PAVO

Phase 2 Terminated

22 enrolled 17 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Pancreatic Neoplasms, Urologic Neoplasms, Endometrial Neoplasms

NCT02327078 2025-08-14

A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)

CNSDermatologicGastrointestinalGynecologicHead & NeckLymphoidThoracic

307 enrolled 27 charts

Glioblastoma, Head and Neck Neoplasms, Lung Neoplasms, Lymphoma, Melanoma, Ovarian Neoplasms, Colorectal Neoplasms

NCT02903914 2025-08-05

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

GastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

260 enrolled 52 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Head and Neck Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms

NCT06048367 2025-08-03

CNSI-Fe(II)

BreastGastrointestinalGynecologicHead & NeckThoracic

19 enrolled 47 charts

Breast Neoplasms, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms

NCT03037385 2025-05-31

ARROW

590 enrolled 58 charts 5 FDA

EndocrineGastrointestinalHead & NeckNETThoracic

Thyroid Cancer, Papillary, Adenocarcinoma, Adenocarcinoma, Papillary, Bronchial Neoplasms, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Colonic Diseases, Colonic Neoplasms, Digestive System Diseases, Digestive System Neoplasms, Endocrine System Diseases, Endocrine Gland Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Thyroid Diseases, Thyroid Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Carcinoma, Medullary, Carcinoma, Neuroendocrine, Neuroendocrine Tumors, Multiple Endocrine Neoplasia Type 2a

NCT04383210 2025-04-03

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

Phase 2 Terminated

54 enrolled 11 charts

BreastGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

Fibromatosis, Gingival, 2, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Uterine Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT03058289 2025-02-27

IT-01

BreastGastrointestinalHead & NeckLymphoidSarcomaThoracic

111 enrolled 21 charts

Diabetes Mellitus, Insulin-Dependent, 12, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Colonic Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Pancreatic Neoplasms, Sarcoma

NCT03127098 2024-08-06

QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer

Phase 1/2 Terminated

3 enrolled 6 charts

BreastGastrointestinalGynecologicHead & NeckThoracic

Breast Neoplasms, Colonic Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Thyroid Neoplasms

NCT04161391 2024-06-13

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Phase 1/2 Terminated

41 enrolled 18 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Thyroid Neoplasms, Carcinoma, Medullary

NCT03665285 2024-03-08

A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

109 enrolled 25 charts

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Transitional Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Endometrial Neoplasms, Cholangiocarcinoma

NCT03403361 2024-03-01

Dual-Energy CT on Plan Quality, Dose-delivery Accuracy, and Simulated Outcomes of Patients Treated With Proton or Photon Therapy

Phase NA Terminated

36 enrolled 5 charts

CNSHead & NeckThoracic

Brain Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT03360695 2024-02-08

Bridge: Proactive Psychiatry Consultation and Case Management for Patients With Cancer

BreastGastrointestinalHead & NeckThoracic

185 enrolled 14 charts

Bipolar Disorder, Breast Neoplasms, Depressive Disorder, Major, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms, Schizophrenia

NCT04155008 2022-11-16

Nutrition and Pharmacological Algorithm for Oncology Patients Study

Phase 4 Terminated

1 enrolled 5 charts

GastrointestinalHead & NeckThoracic

Head and Neck Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Malnutrition

NCT02315066 2022-04-21

Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

174 enrolled 68 charts

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT02178722 2022-02-14

Study to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected Cancers

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

444 enrolled 19 charts

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Melanoma, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Microsatellite Instability, Triple Negative Breast Neoplasms

NCT02318277 2022-01-13

A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203)

176 enrolled 25 charts

Phase EARLY_PHASE1 Completed

Head and Neck Neoplasms, Lung Neoplasms

NCT01434342 2021-09-28

Feasibility of Delivering a Quitline Based Smoking Cessation Intervention in Cancer Patients

146 enrolled 10 charts

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Prostatic Neoplasms, Tobacco Use Disorder, Colorectal Neoplasms

NCT00963911 2021-04-05

ONCODAGE

BreastGastrointestinalGenitourinaryHead & NeckLymphoidThoracic

1,674 enrolled 9 charts

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Prostatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Small Cell Lung Carcinoma

NCT03016403 2021-03-19

A Stepped Care Intervention to Reduce Disparities in Mental Health Services Among Cancer Patients and Caregivers

535 enrolled 29 charts

Phase EARLY_PHASE1 Terminated

Head and Neck Neoplasms, Lung Neoplasms

NCT01479348 2020-06-02

Imaging Study for FdCyd and THU Cancer Treatment

5 enrolled 12 charts

BreastGenitourinaryHead & NeckThoracic

Urinary Bladder Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms

NCT02663817 2020-02-05

DMH-Based Plan Evaluation and Inverse Optimization in Radiotherapy

GenitourinaryHead & NeckThoracic

52 enrolled 6 charts

Head and Neck Neoplasms, Lung Neoplasms, Prostatic Neoplasms

NCT02374255 2019-10-01

Improving Goals of Care Discussion in Advanced Cancer Patients

CNSDermatologicGastrointestinalHead & NeckThoracic

265 enrolled 9 charts

Glioblastoma, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02648178 2019-09-19

Evaluation of Appeal and Impact of E-Cigarettes Among Chronic Smokers With Smoking-Related Cancers

GenitourinaryHead & NeckThoracic

19 enrolled 9 charts

Urinary Bladder Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Tobacco Use Disorder

NCT02966509 2018-10-31

EPAC

CNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

213 enrolled 20 charts

Colonic Neoplasms, Death, Glioblastoma, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Unknown Primary, Prostatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms, Testicular Neoplasms

NCT00896454 2018-10-17

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

BreastGastrointestinalGenitourinaryHead & NeckLymphoidPlasma cellThoracic

33 enrolled 22 charts

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Hypercalcemia, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Parathyroid Neoplasms, Thyroid Neoplasms

NCT00735826 2018-10-12

A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer

GastrointestinalHead & NeckThoracic

10 enrolled 7 charts

Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT01012362 2017-12-28

Study of Pazopanib and Ixabepilone in Patients With Solid Tumors

Phase 1 Terminated

31 enrolled 12 charts

BreastGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

Breast Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Sarcoma

NCT00666978 2017-11-13

Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking

Phase 4 Completed

540 enrolled 25 charts

GastrointestinalGenitourinaryGynecologicHead & NeckOther hematologic neoplasmThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Hypopharyngeal Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Tobacco Use Disorder, Leukemia, Myeloid, Acute, Small Cell Lung Carcinoma

NCT00534001 2017-05-30

Bupropion in Helping Adults Stop Smoking

GastrointestinalGenitourinaryGynecologicHead & NeckOther hematologic neoplasmThoracic

95 enrolled 8 charts

NCT01831726 2017-03-20

SIGNATURE

DermatologicGastrointestinalGynecologicHead & NeckOther hematologic neoplasmSarcomaThoracic

80 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Thyroid Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms, Gastrointestinal Stromal Tumors

NCT00365508 2016-03-29

Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking

Phase 4 Completed

642 enrolled 8 charts

GastrointestinalGenitourinaryGynecologicHead & NeckOther hematologic neoplasmThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Hypopharyngeal Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Tobacco Use Disorder, Tongue Neoplasms, Leukemia, Myeloid, Acute, Small Cell Lung Carcinoma

NCT00565721 2014-08-18

A Proof-of-concept Study to Assess the Ability of [18F]AH-111585 PET Imaging to Detect Tumours and Angiogenesis

CNSDermatologicHead & NeckSarcomaThoracic

33 enrolled 23 charts

Glioma, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Sarcoma

NCT00918281 2014-06-09

Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection

BreastGenitourinaryHead & NeckSarcomaThoracic

70 enrolled 9 charts

Breast Neoplasms, Carcinoma, Renal Cell, Head and Neck Neoplasms, Lung Neoplasms, Sarcoma

NCT00847509 2013-09-27

FLT101

49 enrolled 4 charts

Head and Neck Neoplasms, Lung Neoplasms

NCT00496860 2013-07-22

Safety and Efficacy Study of ALT-801 to Treat Progressive Metastatic Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

26 enrolled 13 charts

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT00527982 2012-12-06

Celecoxib as Adjuvant Biologic Therapy in Patients With Head and Neck and Lung Cancer

Phase 2 Terminated

1 enrolled 2 charts