Clinical Trials

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellSarcomaThoracic

7,000 enrolled

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07327489 2026-01-08

ELEPHAS-05

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

2,000 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Melanoma, Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04490564 2025-12-30

Validation of Molecular Diagnostic Assays to Detect Cancer Biomarkers in Blood and Primary Tumor in HNSCC/NSCLC/Melanoma

DermatologicHead & NeckThoracic

135 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05520099 2025-12-26

ELEPHAS-02

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

416 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT07246759 2025-11-24

NEUTROFLOW

BreastDermatologicGenitourinaryHead & NeckThoracic

600 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Triple Negative Breast Neoplasms

NCT05812027 2025-11-17

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Active not recruiting

1,150 enrolled

DermatologicGynecologicHead & NeckSarcomaThoracic

Uveal Melanoma, Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Sarcoma

NCT06385587 2025-10-20

SYMTECH01

33 enrolled

Head and Neck Neoplasms

NCT05461430 2025-09-15

TraveraRTGx

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

200 enrolled

Anus Neoplasms, Appendiceal Neoplasms, Ascites, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lung Neoplasms, Melanoma, Mesothelioma, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Stomach Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Small Cell, Carcinoma, Pancreatic Ductal, Gastrointestinal Stromal Tumors

NCT06771674 2025-09-09

Real-world Study of First Line Pembrolizumab- or Nivolumab-treated HPV-positive Recurrent/Metastatic Oropharyngeal Squamous Cell Carcinoma

662 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Squamous Cell

NCT05059444 2025-08-22

ORACLE

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

2,020 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Melanoma, Rectal Neoplasms, Ureteral Neoplasms, Endometrial Neoplasms

NCT05406167 2025-08-15

PREMIER

CNSGastrointestinalHead & Neck

Gastrointestinal Neoplasms, Head and Neck Neoplasms, Neoplasms, Urogenital Neoplasms, Central Nervous System Neoplasms

NCT06885424 2025-07-15

DESCENT-1

Enrolling by invitation

400 enrolled

BreastGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Kidney Neoplasms, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04050761 2025-07-02

ProNiHN

502 enrolled

Head and Neck Neoplasms

NCT03114163 2025-06-18

Observational Study of Nivolumab in Participants in Germany With Squamous Cell Carcinoma of the Head and Neck (SCCHN) Progressing on or After Platinum-Based Therapy

485 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcomaThoracic

Head and Neck Neoplasms

NCT05179824 2025-05-06

Tempus Priority Study: A Pan-tumor Observational Study

Active not recruiting

1,000 enrolled

Bile Duct Neoplasms, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Vulvar Neoplasms, Endometrial Neoplasms

NCT03098589 2025-03-30

Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)

Head & NeckLymphoidOther hematologic neoplasm

1,149 enrolled

Sleepiness, Arrhythmias, Cardiac, Cataract, Confusion, Coronary Artery Disease, Digestive System Diseases, Dizziness, Fatigue, Heart Failure, Hemorrhage, Hypersensitivity, Hypotension, Orthostatic, Hypothyroidism, Infections, Lymphoma, Peripheral Nervous System Diseases, Seizures, Thromboembolism, Tumor Lysis Syndrome, Neoplasms, Second Primary, Lung Diseases, Interstitial, Renal Insufficiency, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Teratogenesis

NCT05697198 2025-03-06

PREFER

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

1,429 enrolled

Breast Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rhabdomyosarcoma, Sarcoma, Stomach Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT05451303 2025-01-29

Detection of Oral and Throat Cancers Using OralViome Cancer Testing System

475 enrolled

BreastEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms

NCT04985357 2024-11-25

Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs

Withdrawn

Anus Neoplasms, Appendiceal Neoplasms, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Laryngeal Neoplasms, Lip Neoplasms, Lung Neoplasms, Mesothelioma, Mouth Neoplasms, Neoplasms, Unknown Primary, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Paranasal Sinus Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Thymoma, Vulvar Neoplasms, Pleural Effusion, Malignant, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Carcinoma, Ductal, Small Cell Lung Carcinoma

NCT04622462 2024-11-07

Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment

Squamous Cell Carcinoma of Head and Neck, Disease, Erythroplasia, Hyperplasia, Leukoplakia, Mouth Neoplasms, Keratoderma, Palmoplantar, Epidermolytic

NCT05853783 2024-11-07

Evaluation of Oral Potentially Malignant Disorders (OPMDs) with STRATICYTE™

180 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

Disease, Erythroplasia, Hyperplasia, Leukoplakia, Mouth Diseases, Keratoderma, Palmoplantar, Epidermolytic

NCT06583395 2024-11-01

QUANTUM

Enrolling by invitation

3,000 enrolled

Amyotrophic Lateral Sclerosis, Anxiety Disorders, Arthritis, Rheumatoid, Asthma, Atrial Fibrillation, Brain Neoplasms, Breast Neoplasms, Cerebral Palsy, Cluster Headache, Colitis, Ulcerative, Colonic Neoplasms, Crohn Disease, Deafness, Depression, Diabetes Mellitus, Eczema, Epilepsy, Fibromyalgia, Heart Failure, Hypertension, Hyperthyroidism, Hypothyroidism, Infertility, Leiomyoma, Lung Neoplasms, Lyme Disease, Lymphoma, Macular Degeneration, Migraine Disorders, Multiple Sclerosis, Neoplasms, Osteoarthritis, Osteoporosis, Ovarian Cysts, Ovarian Neoplasms, Parkinson Disease, Phantom Limb, Prostatic Neoplasms, Psoriasis, Skin Neoplasms, Spinal Cord Injuries, Spinal Stenosis, Stress Disorders, Post-Traumatic, Thyroid Neoplasms, Tinnitus, Fatigue Syndrome, Chronic, Tension-Type Headache, Stroke, Pulmonary Disease, Chronic Obstructive, Irritable Bowel Syndrome, Renal Insufficiency, Chronic, Angina, Stable

NCT06618170 2024-10-02

ETCETERA

80 enrolled

Margins of Excision, Carcinoma, Head and Neck Neoplasms

NCT05635266 2024-05-07

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Classical hematologyGenitourinaryHead & NeckLymphoidOther hematologic neoplasmPlasma cell

20,000 enrolled

red meat allergy, Alopecia Areata, Alzheimer Disease, Amyloidosis, Anemia, Sickle Cell, Arthritis, Asthma, Autistic Disorder, Behcet Syndrome, Celiac Disease, Colitis, Ulcerative, Crohn Disease, Cystic Fibrosis, Dermatitis, Atopic, Diabetes Mellitus, Epilepsies, Myoclonic, Fibrosis, Fibromyalgia, Graves Disease, Heart Diseases, Hepatitis, Hypersensitivity, Kidney Diseases, Leukemia, Lupus Erythematosus, Systemic, Lymphoma, Macular Degeneration, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Parkinson Disease, Pemphigus, Psoriasis, Schizophrenia, Spondylitis, Ankylosing, Thyroid Diseases, Vasculitis, Vitiligo, beta-Thalassemia, Hidradenitis Suppurativa, Hepatitis, Autoimmune, Stroke, Pulmonary Disease, Chronic Obstructive, Scleroderma, Diffuse

NCT03157674 2024-01-05

Real-World Evidence and Treatment Patterns: Head and Neck Cancer

43,994 enrolled

Head and Neck Neoplasms

NCT04825873 2023-10-13

A Study to Assess Safety of Nivolumab in Routine Oncology Practice in China

3,102 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung

NCT05994365 2023-08-16

Study of Anlotinib Hydrochloride Capsules in the Treatment of Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Carcinoma

380 enrolled

Thyroid Neoplasms

NCT02303444 2023-06-08

RIFTOS MKI

667 enrolled

Thyroid Neoplasms

NCT05819593 2023-04-19

Evaluating Trends in Anaplastic Thyroid Cancer Patients' Clinical Study Experiences

EndocrineHead & Neck

Thyroid Carcinoma, Anaplastic

NCT05801770 2023-04-06

Discovering Factors in Head and Neck Cancer Patients' Clinical Study Experiences

Head and Neck Neoplasms

NCT05395429 2023-02-23

Clinical Evaluation of Genetron TERT/BRAF PCR Kit in Thyroid Cancer Patients

1,000 enrolled

Thyroid Neoplasms

NCT05685524 2023-01-17

Clinical Study of Pan-cancer DNA Methylation Test in Plasma

GastrointestinalGenitourinaryGynecologicHead & NeckThoracic

3,000 enrolled

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05061940 2022-12-06

This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.

Terminated

22 enrolled

DermatologicHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis

NCT04545632 2022-07-27

DETECT

BreastGastrointestinalGenitourinaryGynecologicHead & Neck

458 enrolled

Breast Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT05068609 2022-05-05

VOLUME-PRO

509 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT03569436 2022-02-10

Effectiveness and Safety of Nivolumab in Participants That Have Head and Neck Cancer That Has Come Back or Has Spread

262 enrolled

Head and Neck Neoplasms

NCT05123950 2021-11-17

A Study of Treatment Patterns and Clinical Outcomes in First Line Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (1L R/M SCCHN) Participants in Europe

304 enrolled

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT05049408 2021-09-28

Verification of Saliva MMP-1 as a Diagnostic Marker of Oral Cavity Cancer

1,160 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Mouth Neoplasms

NCT05025046 2021-09-13

NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules

400 enrolled

Thyroid Neoplasms, Thyroid Nodule

NCT03239834 2021-08-12

Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-Making

893 enrolled

Gingival Neoplasms, Leukoplakia, Oral, Lip Neoplasms, Oropharyngeal Neoplasms, Palatal Neoplasms, Tongue Neoplasms, Oral Ulcer

NCT04697446 2021-08-10

External Control, Observational, Retrospective Study Comparing Pralsetinib to Best Available Therapy in Patients With RET-Fusion Positive NSCLC

279 enrolled

Head & NeckThoracic

Bronchial Diseases, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT03896958 2020-12-04

PIONEER

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

1,000 enrolled

Adenocarcinoma of Lung, Adrenal Gland Neoplasms, Anus Neoplasms, Bile Duct Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Neoplasms, Unknown Primary, Neurologic Manifestations, Oligodendroglioma, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Uterine Neoplasms, Vulvar Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Thyroid Carcinoma, Anaplastic

NCT03479463 2020-11-13

Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy

Terminated

8 enrolled

Laryngeal Neoplasms, Pharyngeal Neoplasms

NCT02430714 2020-01-09

Post-marketing Surveillance of Lenvatinib Mesylate (Lenvima Capsule) in Patients With Unresectable Thyroid Cancer (Study LEN01T)

629 enrolled

Thyroid Neoplasms

NCT04066335 2019-12-18

Study to Evaluate the Safety of Nanoxel M Inj.

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

1,498 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Stomach Neoplasms

NCT01587573 2018-04-12

Developing an In-vitro Diagnostic Risk-Stratification Test for Oral Cancer

370 enrolled