Clinical Trials

50 enrolled

Head and Neck Fibrosis

NCT05389306 2026-03-03

NPC-LN

348 enrolled

Nasopharyngeal Carcinoma, Disease

NCT02031250 2026-03-02

Randomized Phase II Study of DCE-MRI-based Dose Escalation for Poor-prognosis and Neck Cancer

106 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck

NCT00003809 2026-02-27

Cisplatin With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer

Phase 3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT02589938 2026-02-27

ACUPUNCTURE

258 enrolled 16 charts

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Xerostomia

NCT04290546 2026-02-27

CIML NK Cell in Head & Neck Cancer

11 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT05115825 2026-02-27

Pain Management for Head and Neck Cancer Survivors

33 enrolled

Head and Neck Carcinoma

NCT07435311 2026-02-27

A Phase I Comparative Study of Pharmacokinetics, Safety, and Efficacy of RPH-002 and Erbitux® in Unresectable Metastatic or Recurrent Head and Neck Squamous Cell Carcinoma

118 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT07419113 2026-02-24

UNOS

45 enrolled

Head and Neck Neoplasms

NCT03656133 2026-02-20

Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy for HPV + Oropharyngeal Cancers

55 enrolled 10 charts

Laryngeal Diseases, Oropharyngeal Neoplasms

NCT04372914 2026-02-20

Prevention of Oral DNA Damage by Black Raspberries

69 enrolled 14 charts

Mouth Neoplasms, Smoking

NCT03953976 2026-02-19

INRT-AIR: A Prospective Phase II Study of Involved Nodal Radiation Therapy

67 enrolled 16 charts

Squamous Cell Carcinoma of Head and Neck

NCT03757091 2026-02-18

Flexible Intubation Scope With or Without Video Laryngoscope in Supporting Endotracheal Tube Placement in Patients With Head and Neck Cancer Before Surgery

143 enrolled 10 charts

Head and Neck Neoplasms

NCT03480672 2026-02-17

Postoperative aRCH With Cisplatin Versus aRCH With Cisplatin and Pembrolizumab in Locally Advanced Head and Neck Squamous Cell Carcinoma

211 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT06073223 2026-02-17

Intervention to Decrease Overtreatment of Patients With Low-risk Thyroid Cancer

50 enrolled

Thyroid Neoplasms

NCT03993353 2026-02-12

Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer

GastrointestinalHead & Neck

7 enrolled 14 charts

Pyridoxine-dependent epilepsy, Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Esophageal Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Neoplasm Metastasis, Neoplasms

NCT01932697 2026-02-10

Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer

81 enrolled 18 charts

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT05083416 2026-02-09

Effect of Prolonged Nightly Fasting on Immunotherapy Outcomes in HNSCC - Role of Gut Microbiome

29 enrolled

Intermittent Fasting, Head and Neck Neoplasms

NCT03258554 2026-02-06

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Phase 2/3 Completed

196 enrolled 31 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

NCT02973386 2026-02-05

Prognostic Analysis of Concurrent Chemoradiotherapy With/Without Adjuvant Chemotherapy for Locally Advanced NPC Patients

Phase 3 Completed

294 enrolled

Nasopharyngeal Carcinoma

NCT06235814 2026-02-05

MAPS

2 enrolled

EndocrineHead & Neck

Thyroid Cancer, Papillary

NCT02979977 2026-02-04

Dual Inhibition of EGFR With Afatinib and Cetuximab in the Treatment of Advanced Squamous Cell Cancers of the Head and Neck

50 enrolled 14 charts

Squamous Cell Cancers of the Head and Neck

NCT02989064 2026-02-04

MAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck Cancers

DermatologicGenitourinaryHead & Neck

10 enrolled

Carcinoma, Transitional Cell, Head and Neck Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms

NCT03040999 2026-02-04

KEYNOTE-412

Phase 3 Completed

804 enrolled 20 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT04284540 2026-02-03

Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma

37 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT07376213 2026-02-02

Effects of a Home-Based Exercise Program During Radiotherapy

24 enrolled

Head and Neck Neoplasms, Lymphedema, Motor Activity

NCT07378345 2026-01-30

DigiComSurg

155 enrolled

Squamous Cell Carcinoma of Head and Neck, Communication

NCT05763615 2026-01-29

IMAG 2 ORL

7 enrolled

Congenital Abnormalities, Head and Neck Neoplasms

NCT03082534 2026-01-28

Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma

78 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Neoplasm Metastasis, Oropharyngeal Neoplasms, Recurrence

NCT04640480 2026-01-27

Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors

BreastGastrointestinalGynecologicHead & NeckThoracic

21 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Small Cell Lung Carcinoma

NCT05979883 2026-01-26

Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning

204 enrolled

Head and Neck Neoplasms

NCT04593277 2026-01-23

Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study

GastrointestinalHead & NeckLymphoidOther hematologic neoplasmSarcoma

549 enrolled

Leukemia, Lymphoma, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT03829722 2026-01-22

Radiotherapy, Carboplatin/Paclitaxel and Nivolumab for High Risk HPV-related Head and Neck Cancer

26 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck

NCT02862678 2026-01-21

ORODIFF

59 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04139057 2026-01-20

EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC

Phase 1/2 Completed

10 enrolled

Squamous Cell Carcinoma of Head and Neck

NCT04509726 2026-01-20

EBV Specific Cytokine Secreting TCR-T Cells in the Treatment of EBV-Positive Metastatic/Refractory Nasopharyngeal Carcinoma

Phase 1/2 Completed

9 enrolled