Clinical Trials

400 enrolled

Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

NCT03480360 2026-02-19

Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

21 enrolled 19 charts

Anemia, Refractory, with Excess of Blasts, Lymphoma, Lymphoma, Non-Hodgkin, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Neoplasms, Plasma Cell, Primary Myelofibrosis

NCT05456191 2026-02-06

ASC4START

568 enrolled

Leukemia, Myeloproliferative Disorders, Philadelphia Chromosome, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT06093672 2026-01-27

GIV-IN-PV

220 enrolled

Polycythemia Vera

NCT04266301 2026-01-13

STIMULUS-MDS2

530 enrolled 29 charts

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT03594149 2026-01-02

AZABAC

60 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05457556 2025-12-22

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

LymphoidMyeloidOther hematologic neoplasm

435 enrolled

Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04576156 2025-12-04

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

327 enrolled

Myeloproliferative Disorders, Polycythemia, Thrombocytosis, Primary Myelofibrosis

NCT03808805 2025-12-03

APHYPAP

63 enrolled

Myeloproliferative Disorders

NCT04064060 2025-11-12

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

665 enrolled

Myelodysplastic Syndromes, Myeloproliferative Disorders, beta-Thalassemia

NCT03268954 2025-10-29

PANTHER

454 enrolled 41 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT04562389 2025-10-03

SENTRY

353 enrolled

Myeloproliferative Disorders, Primary Myelofibrosis

NCT02201459 2025-10-02

PETALs

200 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT04551053 2025-10-02

To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304)

177 enrolled 15 charts

Myeloproliferative Disorders, Primary Myelofibrosis

NCT03952039 2025-08-28

FREEDOM2

202 enrolled 23 charts

Myeloproliferative Disorders, Primary Myelofibrosis

NCT04285086 2025-08-13

SURPASS ET

174 enrolled

Myeloproliferative Disorders, Thrombocythemia, Essential

NCT05481151 2025-08-13

A Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV

111 enrolled

Polycythemia, Polycythemia Vera, Thrombocythemia, Essential

NCT06468033 2025-08-13

P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk

150 enrolled

Myeloproliferative Disorders, Primary Myelofibrosis

NCT05210790 2025-08-07

VERIFY

293 enrolled

Polycythemia Vera

NCT06033586 2025-08-06

THRIVE

46 enrolled

Polycythemia Vera

NCT02521493 2025-08-01

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

280 enrolled 13 charts

Down Syndrome, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

NCT04717414 2025-07-10

INDEPENDENCE

Classical hematologyMyeloid

313 enrolled

Anemia, Myeloproliferative Disorders, Primary Myelofibrosis

NCT06423911 2025-06-03

POLARIS-2

285 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT05413915 2025-05-21

Asciminib Used in Consolidation With Imatinib vs. Imatinib to Achieve TFR in CP-CML

164 enrolled

Phase 3 Not yet recruiting

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT06927232 2025-04-15

AZA+Lus VS AZA Monotherapy in HR-MDS

86 enrolled

Higher-risk Myelodysplastic Syndrome

NCT03106779 2025-04-08

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

233 enrolled 10 charts 1 FDA

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT03016130 2025-04-07

UF-BMT-LDND-101

217 enrolled

Infections, Leukemia, Myelodysplastic Syndromes

NCT05883956 2025-03-20

PREFER-HMA

13 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Patient Preference

NCT04472598 2025-02-21

TRANSFORM-1

252 enrolled

Neoplasms, Primary Myelofibrosis

NCT05991908 2025-02-18

Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies

222 enrolled

Phase 3 Enrolling by invitation

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05674539 2025-02-10

Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome

200 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03755518 2024-12-12

FREEDOM

38 enrolled 23 charts

Myeloproliferative Disorders, Primary Myelofibrosis

NCT04116502 2024-11-18

MITHRIDATE

586 enrolled

Polycythemia Vera

NCT04655092 2024-11-08

Extension Study of P1101 After Completion of Phase 2 Study in PV Patients or Phase 3 Study in ET Patients

67 enrolled

Myeloproliferative Disorders, Polycythemia Vera

NCT06002490 2024-11-08

A Study to Evaluate P1101 in Japanese PV Patients

21 enrolled

Myeloproliferative Disorders, Polycythemia Vera

NCT03459534 2024-10-28

A Phase 3 Study for the Efficacy and Safety of Radotinib in CP-CML Patients With Failure or Intolerance to Previous TKIs

173 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT02907359 2024-08-27

Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs

417 enrolled 24 charts

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT03306264 2024-08-27

Study of ASTX727 vs IV Decitabine in Participants With MDS, CMML, and AML

227 enrolled 37 charts 2 FDA

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT02326311 2024-08-13

Optimization of TKIs Treatment and Quality of Life in Ph+ CML Patients ≥60 Years in Deep Molecular Response

229 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00043381 2024-08-02

Decitabine Versus Supportive Care in Adults With Advanced-stage MDS

160 enrolled

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT05753384 2024-07-29

Discontinuation of TyrosIne Kinase Inhibitors (TKI) in Chronic Myeloid Leukemia (CML) and Impact on the Immune System

140 enrolled

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT03401060 2024-05-03

DenosuMast

24 enrolled

Osteoporosis, Mastocytosis, Systemic

NCT04842604 2023-12-18

Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML

14 enrolled 11 charts