Clinical Trials

Constipation, Diarrhea, Melena, Abdominal Pain

NCT03499808 2025-09-09

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

GastrointestinalOtherPlasma cell

43 enrolled 23 charts

Lymphadenopathy, Immunoglobulin Light-chain Amyloidosis, Constipation, Diarrhea, Gastrointestinal Hemorrhage, Hepatomegaly, Macroglossia, Nausea, Purpura

NCT04031469 2025-07-31

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Suspended

1,000 enrolled

GastrointestinalOtherOther solid neoplasmThoracic

Autism Spectrum Disorder, Bipolar and Related Disorders, Post-Lyme Disease Syndrome, Generalized Anxiety Disorder, Acne Vulgaris, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Anxiety Disorders, Arthritis, Rheumatoid, Autistic Disorder, Bipolar Disorder, Celiac Disease, Colitis, Ulcerative, Colonic Neoplasms, Compulsive Personality Disorder, Constipation, Crohn Disease, Depression, Depressive Disorder, Major, Diabetes Mellitus, Eczema, Epidermolysis Bullosa, Gout, Hypercholesterolemia, Lyme Disease, Mesothelioma, Migraine Disorders, Multiple Sclerosis, Myasthenia Gravis, Neoplasms, Obsessive-Compulsive Disorder, Parkinson Disease, Psoriasis, Colorectal Neoplasms, Fatigue Syndrome, Chronic, Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Relapsing-Remitting, Lyme Neuroborreliosis, Irritable Bowel Syndrome

NCT07038551 2025-07-02

Prophylactic Use of Naldemedine on Opioid-induced Nausea and Vomiting in Patients With Cancer: POSEIDON Study

Phase 4 Recruiting

120 enrolled

Phase NA Not yet recruiting

Opioid-Induced Constipation, Constipation, Nausea, Vomiting

NCT05805436 2025-05-30

Preop Laxatives in Robotic Urologic Surgery

Phase 4 Recruiting

240 enrolled

GenitourinaryOther

Constipation, Kidney Neoplasms, Prostatic Neoplasms

NCT06924645 2025-04-11

FMT-NENs

40 enrolled

Constipation, Nausea, Vomiting

NCT05059756 2023-11-22

PTNS and PFR in the Treatment of Childhood Constipation

LymphoidOtherOther hematologic neoplasm

84 enrolled

Constipation, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Pelvic Floor Disorders

NCT02921802 2022-06-14

A Study of Special Use Results Surveillance of Revlimid 5mg Capsules

Classical hematologyMyeloidOtherPlasma cell

4,626 enrolled

Arrhythmias, Cardiac, Constipation, Diarrhea, Heart Failure, Hemorrhage, Hypersensitivity, Infections, Multiple Myeloma, Myelodysplastic Syndromes, Myocardial Infarction, Neutropenia, Peripheral Nervous System Diseases, Thrombocytopenia, Tumor Lysis Syndrome, Lung Diseases, Interstitial, Renal Insufficiency, Venous Thromboembolism, Teratogenesis

NCT02922543 2022-06-14

A Safety and Efficacy Study of Revlimid® 5 mg Capsules in Patients With Relapsed or Refractory Multiple Myeloma Who Have Received Long-term Treatment With it Under the Actual Condition of Use

Classical hematologyOtherPlasma cell

361 enrolled

Arrhythmias, Cardiac, Constipation, Diarrhea, Heart Failure, Hemorrhage, Hypersensitivity, Infections, Multiple Myeloma, Myocardial Infarction, Neutropenia, Peripheral Nervous System Diseases, Thrombocytopenia, Tumor Lysis Syndrome, Lung Diseases, Interstitial, Renal Insufficiency, Venous Thromboembolism, Teratogenesis

NCT04318808 2022-03-10

Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer

Phase NA Unknown

74 enrolled

CNSLymphoidOtherOther hematologic neoplasm

Constipation

NCT03981510 2020-11-25

Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation

Phase NA Unknown

80 enrolled

Constipation, Neurofibromatosis 1, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02745353 2019-12-09

Naloxegol in Cancer Opioid-Induced Constipation

Phase 2 Terminated

7 enrolled 9 charts

Constipation, Neoplasms

NCT01189409 2019-08-28

Polyethylene Glycol (PEG) Versus Sennosides Study in Opioid-Induced Constipation in Cancer Patients

Phase 4 Terminated

70 enrolled 12 charts

Constipation, Neoplasms

NCT02839889 2019-03-05

Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)

Phase 4 Terminated

12 enrolled 33 charts

Constipation, Neoplasms, Pain

NCT01696643 2018-11-15

Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

1,407 enrolled 15 charts

Opioid-Induced Constipation, Bronchiolitis Obliterans Syndrome, Constipation, Pain

NCT01901302 2018-11-15

Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

61 enrolled 4 charts

Opioid-Induced Constipation, Bronchiolitis Obliterans Syndrome, Constipation, Pain

NCT01901341 2018-11-15

The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

44 enrolled 6 charts

Opioid-Induced Constipation, Bronchiolitis Obliterans Syndrome, Constipation, Pain

NCT00728975 2018-11-05

The Bowel Research Collaborative Data Tracking System Implementation Study

533 enrolled

Constipation, Neoplasms

NCT00513656 2018-10-23

A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain

230 enrolled

Bronchiolitis Obliterans Syndrome, Constipation, Neoplasms, Pain

NCT03208816 2018-03-27

CLARO

25 enrolled

Anxiety Disorders, Constipation, Depression, Fatigue, Neoplasms, Pain, Vomiting

NCT02422329 2018-03-22

Changes in Patient Reported Constipation Among Advanced Cancer Patients After Receiving an Educational Intervention

59 enrolled

Constipation, Neoplasm Metastasis, Recurrence

NCT02121626 2017-11-22

FOCCUS

248 enrolled

GastrointestinalOther

Anorexia, Constipation, Deglutition Disorders, Diarrhea, Flatulence, Gastroesophageal Reflux, Nausea, Neoplasms, Pain, Exocrine Pancreatic Insufficiency, Vomiting, Weight Loss, Steatorrhea, Mucositis

NCT02658201 2017-10-13

FIESTA

11 enrolled

Constipation

NCT00241722 2017-08-30

Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

Phase 3 Completed

805 enrolled

Constipation, Intestinal Diseases, Pain

NCT02958566 2017-03-20

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Phase 4 Unknown

80 enrolled

GastrointestinalOther

Agnosia, Colonic Neoplasms, Constipation, Diverticulitis, Colonic, Pain, Postoperative, Rectal Neoplasms, Diverticulosis, Colonic, Ileus

NCT01416909 2017-02-23

Managing Medication-induced Constipation in Cancer: A Clinical Trial

601 enrolled

Constipation

NCT01473290 2016-07-06

Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy

Phase 3 Withdrawn

Constipation, Diarrhea, Fatigue, Intestinal Obstruction

NCT01004393 2016-02-02

Methylnaltrexone for Opioid-induced Constipation in Cancer Patients

12 enrolled 10 charts

Constipation, Opioid-Related Disorders, Neoplasms

NCT00425906 2016-01-12

Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer

Phase NA Withdrawn

Anorexia, Constipation, Intestinal Obstruction, Pain

NCT01014559 2015-09-28

OXN3505

225 enrolled

Constipation, Pain

NCT00135577 2015-09-02

Study 767905/008 Extension Study: Alvimopan for Treatment of Opioid-Induced Bowel Dysfunction in Cancer Pain Subjects

67 enrolled

Opioid-Induced Constipation, Constipation, Intestinal Diseases, Neoplasms

NCT00256932 2015-09-02

Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

Phase 3 Completed

518 enrolled

Constipation, Intestinal Diseases, Pain

NCT00259922 2015-09-02

Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain

Phase 3 Completed

485 enrolled

Constipation, Intestinal Diseases, Pain

NCT00331045 2015-09-02

Clinical Evaluation Of Alvimopan (SB767905) On Constipation And Related Symptoms Associated With Opioid

Phase 2 Terminated

21 enrolled

Constipation, Neoplasms

NCT00487409 2014-12-15

Random Comparison of LigaSure and Disposable Staples for Laparoscopic Surgery

100 enrolled

GastrointestinalOther

Colitis, Ulcerative, Colonic Diseases, Constipation, Crohn Disease, Diverticulitis, Endometriosis, Rectal Diseases

NCT00536523 2014-08-22

Effect of Serotonin Level on Constipation Caused by Chemotherapy in Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Terminated

13 enrolled

GynecologicOther

Carcinoma, Ovarian Epithelial, Constipation, Fallopian Tube Neoplasms, Intestinal Obstruction, Ovarian Neoplasms

NCT00984334 2013-12-27

Naloxone SR Capsules in Patients With Opioid Induced Constipation

40 enrolled 12 charts

Opioid-Induced Constipation, Constipation, Pain, Chronic Pain

NCT00004895 2012-06-06

Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery