Clinical Trials

Opioid-Induced Constipation, Neoplasms

NCT07038551 2025-07-02

Prophylactic Use of Naldemedine on Opioid-induced Nausea and Vomiting in Patients With Cancer: POSEIDON Study

Phase 4 Recruiting

120 enrolled

Opioid-Induced Constipation, Constipation, Nausea, Vomiting

NCT05133076 2025-06-26

OIC1

14 enrolled

Opioid-Induced Constipation

NCT05149833 2025-04-03

E-StOIC

1,200 enrolled

Phase 4 Not yet recruiting

Opioid-Induced Constipation

NCT06897917 2025-03-27

Real World Study of Oxycodone/Naloxone Sustained-Release Tablets (Mimeixin) for Patients With Severe Cancer Pain

203 enrolled

Cancer Pain, Opioid-Induced Constipation

NCT03720613 2025-02-12

Risk of Major Adverse Cardiovascular Events for Naldemedine & Other Medications for Opioid Induced Constipation

Recruiting

34,532 enrolled

Opioid-Induced Constipation

NCT05216328 2024-11-22

OMAMA

Phase 4 Recruiting

330 enrolled

Cancer Pain, Opioid-Induced Constipation, Neoplasms

NCT04294550 2022-02-28

Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol

250 enrolled

Opioid-Induced Constipation, Neoplasms

NCT01117051 2021-06-11

OIC

174 enrolled 11 charts

Opioid-Induced Constipation

NCT04404933 2020-05-28

StOIC-2

100 enrolled

Cancer Pain, Opioid-Induced Constipation, Neoplasms

NCT04350112 2020-04-16

StOIC-1

1,007 enrolled

Cancer Pain, Opioid-Induced Constipation, Neoplasms

NCT00858754 2019-11-29

Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects

Phase 4 Withdrawn

Opioid-Induced Constipation

NCT02270983 2019-04-08

Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain

254 enrolled 23 charts

Opioid-Induced Constipation

NCT01696643 2018-11-15

Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

1,407 enrolled 15 charts

Opioid-Induced Constipation, Bronchiolitis Obliterans Syndrome, Constipation, Pain

NCT01901302 2018-11-15

Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

61 enrolled 4 charts

Opioid-Induced Constipation, Bronchiolitis Obliterans Syndrome, Constipation, Pain

NCT01901341 2018-11-15

The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation

44 enrolled 6 charts

Opioid-Induced Constipation, Bronchiolitis Obliterans Syndrome, Constipation, Pain

NCT01395524 2017-02-23

A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Phase 3 Completed

302 enrolled 13 charts

Opioid-Induced Constipation

NCT00135577 2015-09-02

Study 767905/008 Extension Study: Alvimopan for Treatment of Opioid-Induced Bowel Dysfunction in Cancer Pain Subjects

67 enrolled

Opioid-Induced Constipation, Constipation, Intestinal Diseases, Neoplasms

NCT01323790 2015-06-02

Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Phase 3 Completed

700 enrolled 25 charts

Opioid-Induced Constipation

NCT01309841 2015-06-01

Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Phase 3 Completed

652 enrolled 25 charts

Opioid-Induced Constipation

NCT01384292 2015-06-01

Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain

14 enrolled 7 charts

Cancer Pain, Opioid-Induced Constipation

NCT00984334 2013-12-27

Naloxone SR Capsules in Patients With Opioid Induced Constipation

40 enrolled 12 charts

Opioid-Induced Constipation, Constipation, Pain, Chronic Pain

NCT00399659 2012-05-01

Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.

360 enrolled

Opioid-Induced Constipation, Constipation

NCT00365820 2012-04-20

Efficacy and Safety of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain

Phase 2/3 Terminated

670 enrolled

Opioid-Induced Constipation, Constipation

NCT00414024 2012-04-20

Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.

11 enrolled