Clinical Trials

Anemia, Lymphopenia, Neutropenia, Thrombocytopenia, Hematologic Neoplasms

NCT06245746 2025-03-21

UCMSC-Exo for Chemotherapy-induced Myelosuppression in Acute Myeloid Leukemia

Phase 1 Recruiting

9 enrolled

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

Anemia, Hemorrhage, Infections, Neutropenia, Thrombocytopenia, Leukemia, Myeloid, Acute

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Phase 1 Terminated

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT06250595 2024-02-09

ENROL

Recruiting

37,090 enrolled

Classical hematologyOther hematologic neoplasmPlasma cell

Bone Marrow Failure Disorders, Anemia, Anemia, Sickle Cell, Leukemia, Thalassemia, Iron Metabolism Disorders, Hematologic Neoplasms, Hemostatic Disorders, Neoplasms, Plasma Cell

NCT03010358 2023-08-08

Entospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma

Phase 1/2 Completed

24 enrolled 16 charts

Classical hematologyLymphoidOther hematologic neoplasm

Anemia, Leukemia, Hairy Cell, Lymphoma, Follicular, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Prolymphocytic, B-Cell

NCT05672420 2023-01-05

Umbilical Cord Derived Mesenchymal Stem Cells for Treatment-induced Myelosuppression in Hematologic Malignancies

Phase 1/2 Unknown

181 enrolled

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

Anemia, Hemorrhage, Infections, Leukemia, Lymphoma, Multiple Myeloma, Neutropenia, Thrombocytopenia, Hematologic Neoplasms

NCT02452983 2022-06-02

SS1

Phase 1 Terminated

14 enrolled

Classical hematologyMyeloidOther hematologic neoplasm

Cytopenia, Anemia, Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Preleukemia

NCT02948283 2021-02-12

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

Phase 1 Completed

3 enrolled

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

Lymphadenopathy, Anemia, Fatigue, Fever, Lymphocytosis, Multiple Myeloma, Splenomegaly, Thrombocytopenia, Weight Loss, Leukemia, Lymphocytic, Chronic, B-Cell

NCT02730884 2020-08-07

Single-Arm Study of the Efficacy and Safety of Oral Rigosertib in Patients With Myelofibrosis (MF) and Anemia

Phase 2 Terminated

3 enrolled 6 charts

Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Leukemia, Splenomegaly, Primary Myelofibrosis

NCT00070382 2020-08-03

Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer

Classical hematologyDermatologicLymphoidOther hematologic neoplasmOther neoplasmPlasma cell

14 enrolled

Immunoglobulin Light-chain Amyloidosis, Anemia, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Mycosis Fungoides, Precancerous Conditions, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell

NCT02530515 2019-10-29

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

Classical hematologyLymphoidOther hematologic neoplasm

8 enrolled 6 charts

Lymphadenopathy, Anemia, Communicable Diseases, Fever, Lymphocytosis, Thrombocytopenia, Weight Loss, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Neoplasms, Second Primary

NCT00003398 2019-10-17

Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

Phase 4 Completed

45 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Anemia, Blast Crisis, Burkitt Lymphoma, Graft vs Host Disease, Hodgkin Disease, Leukemia, Leukemia, Megakaryoblastic, Acute, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Myelodysplastic Syndromes, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Dendritic Cell Sarcoma, Interdigitating

NCT01392989 2019-05-07

Post T-plant Infusion of Allogeneic Cytokine Induced Killer (CIK) Cells as Consolidative Therapy in Myelodysplastic Syndromes/Myeloproliferative Disorders

Classical hematologyMyeloidOther hematologic neoplasm

44 enrolled 13 charts

Anemia, Leukemia, Myeloid, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neural Tube Defects

NCT00801931 2019-03-27

Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders

Phase 1/2 Terminated

1 enrolled 8 charts

CNSClassical hematologyLymphoidOther hematologic neoplasm

Anemia, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Neuroblastoma

NCT03086252 2018-07-26

Patient-Driven Transfusion Thresholds in Hematological Disorders: A Pilot Study

Phase NA Withdrawn

Classical hematologyMyeloidOther hematologic neoplasm

Bone Marrow Failure Disorders, Anemia, Anemia, Aplastic, Leukemia, Myelodysplastic Syndromes, Hematologic Neoplasms

NCT00987480 2018-07-10

Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine

Classical hematologyMyeloidOther hematologic neoplasm

45 enrolled 12 charts

Anemia, Anemia, Aplastic, Leukemia, Myelodysplastic Syndromes

NCT00281892 2018-05-11

Fludarabine and Darbepoetin Alfa in Treating Older Patients With Chronic Lymphocytic Leukemia

Classical hematologyLymphoidOther hematologic neoplasm

97 enrolled

Anemia, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00701844 2017-11-17

Sharing Our Strength: A Research Study for Bone Marrow/Stem Cell Transplant Survivors

Phase NA Completed

315 enrolled

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

Anemia, Anemia, Aplastic, Immunoproliferative Disorders, Leukemia, Leukemia, Lymphoid, Lymphatic Diseases, Lymphoma, Lymphoproliferative Disorders, Multiple Myeloma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01034592 2017-08-02

Pilot Lenalidomide in Adult Diamond-Blackfan Anemia Patients w/ RBC Transfusion-Dependent Anemia

Phase 1 Terminated

2 enrolled 9 charts

Classical hematologyMyeloidOther hematologic neoplasm

Anemia, Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00416624 2017-02-10

Epoetin Alfa or Darbepoetin Alfa in Treating Patients With Anemia Caused by Chemotherapy

Classical hematologyDermatologicLymphoidOther hematologic neoplasmOther neoplasmPlasma cell

239 enrolled 23 charts

Immunoglobulin Light-chain Amyloidosis, Anemia, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Mycosis Fungoides, Precancerous Conditions, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell

NCT00278265 2016-10-03

Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic Leukemia

Phase 2 Terminated

12 enrolled

Anemia, Neutropenia, Leukemia, Large Granular Lymphocytic

NCT02860598 2016-08-09

EPREX/LAM-ALLO

Unknown

104 enrolled

Anemia, Leukemia, Myeloid, Acute

NCT00058331 2016-07-18

Epoetin Alfa in Treating Anemia in Patients With Solid Tumors

Classical hematologyLymphoidOther hematologic neoplasmOther neoplasmPlasma cell

365 enrolled

Anemia, Leukemia, Lymphoma, Lymphoproliferative Disorders, Multiple Myeloma, Precancerous Conditions, Neoplasms, Plasma Cell

NCT00003600 2016-07-13

Epoetin Alfa in Treating Anemia in Patients Who Are Receiving Chemotherapy

BreastClassical hematologyLymphoidMyeloidOther hematologic neoplasmOther neoplasmPlasma cellThoracic

344 enrolled

Anemia, Breast Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Multiple Myeloma, Myeloproliferative Disorders, Precancerous Conditions, Neoplasms, Plasma Cell, Drug-Related Side Effects and Adverse Reactions

NCT00031980 2016-07-06

Cyclosporine in Treating Patients With Low Blood Counts Caused By Hematologic Cancer

Classical hematologyLymphoidOther hematologic neoplasm

30 enrolled

Anemia, Leukemia, Neutropenia, Thrombocytopenia, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Large Granular Lymphocytic

NCT01135849 2015-11-17

B-Receptor Signaling in Cardiomyopathy

Completed

99 enrolled

BreastCNSClassical hematologyDermatologicEndocrineGastrointestinalGenitourinaryHead & NeckLymphoidMyeloidNETOther hematologic neoplasmOther solid neoplasmPlasma cellSarcomaThoracic

Amyloidosis, Anemia, Anus Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Renal Cell, Colonic Neoplasms, Endocrine Gland Neoplasms, Esophageal Neoplasms, Eye Neoplasms, Gallbladder Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Leukemia, Lung Neoplasms, Lymphoma, Non-Hodgkin, Mesothelioma, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neurologic Manifestations, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Neuroendocrine Tumors, Gastrointestinal Stromal Tumors

NCT00003538 2014-05-02

Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation

Phase NA Completed

BreastCNSClassical hematologyGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Carcinoma, Ovarian Epithelial, Anemia, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Graft vs Host Disease, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00003341 2013-07-03

Epoetin Alfa in Treating Anemia in Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma and Anemia Caused By Chemotherapy

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

275 enrolled

Anemia, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Neoplasms, Plasma Cell

NCT00004215 2013-06-19

Leridistim Compared With Filgrastim in Treating Older Patients With Acute Myeloid Leukemia

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Anemia, Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Neutropenia, Thrombocytopenia, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00301912 2012-10-02

Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Phase 2 Withdrawn

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Anemia, Blast Crisis, Burkitt Lymphoma, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00661999 2011-05-17

Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer

Classical hematologyDermatologicLymphoidOther hematologic neoplasmOther neoplasmPlasma cell

502 enrolled 30 charts

Immunoglobulin Light-chain Amyloidosis, Anemia, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Leukemia, Mast-Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Mycosis Fungoides, Precancerous Conditions, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Lymphoma, Extranodal NK-T-Cell

NCT00145652 2007-07-30

Adjuvant I.V. Iron Therapy During Erythropoetin Treatment of Anemic Patients With Lymphoproliferative Disorders.