Clinical Trials

69 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT04284228 2024-01-16

Antigen-specific T Cell Therapy for AML or MDS Patients With Relapsed Disease After Allo-HCT

22 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03614858 2023-11-29

CD19/CD22-targeted Chimeric Antigen Receptor Engineered T Cell (CART) in B-Cell Acute Lymphoblastic Leukemia.

Leukemia, B-Cell

NCT03896854 2023-11-29

CART-19 T Cell in CD19 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

15 enrolled

Leukemia, Myeloid, Acute

NCT06087419 2023-11-02

A Prospective Clinical Study of Bridging alloHSCT After Treatment With Obinutuzumab in Combination With Chidamide and Venetoclax in RR Ph-ALL and B-cell Lymphoma Patients

42 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04964518 2023-10-25

A Study of APG-2575 in Combination With Azacitidine in Patients With Acute Myeloid Leukemia (AML)

24 enrolled

Leukemia, Myeloid, Acute

NCT03867682 2023-08-04

Venetoclax and Lintuzumab-Ac225 in AML Patients

38 enrolled

Leukemia, Myeloid, Acute

NCT05949762 2023-07-18

Safety and Efficacy of Venetoclax in Combination With Azacitidine and HA Regimen in the Treatment of AML in the Elderly

45 enrolled

Leukemia, Myeloid, Acute

NCT02825836 2023-07-13

Phase I/II, FIH, Dose Escalation Trial of TL-895 and Expansion of TL-895 Monotherapy and Combination Therapy With Navtemadlin in Tx-Naïve and R/R CLL/SLL Subjects

130 enrolled

Lymphoma, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Mantle-Cell

NCT05932173 2023-07-11

A Study of Novel Anti-CD19 CAR-T in Patients With r/r B-Cell Malignancies

60 enrolled

Leukemia, Lymphoma, Leukemia, B-Cell, Lymphoma, B-Cell

NCT05140811 2023-05-24

A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome

126 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT04265963 2023-04-18

CD123-Targeted CAR-T Cell Therapy for Relapsed/Refractory Acute Myeloid Leukemia

45 enrolled

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT04271410 2023-04-18

CD19+Targeted CAR-T Cell Therapy for Relapsed/Refractory CD19+ B Cell Leukemia and Lymphoma

80 enrolled

Leukemia, Lymphoma, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse

NCT04271800 2023-04-18

Safety and Efficacy of CD19-Targeted CAR-T Therapy for Relapsed/Refractory CD19+ B Cell Leukemia and Lymphoma

Leukemia, Lymphoma, Leukemia, B-Cell, Leukemia, Lymphocytic, Chronic, B-Cell

NCT04272125 2023-04-18

Safety and Efficacy of CD123-Targeted CAR-T Therapy for Relapsed/Refractory Acute Myeloid Leukemia

Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute

NCT04648475 2023-04-18

Safety and Efficacy of CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Leukemia and Lymphoma

Leukemia, B-Cell, Lymphoma, B-Cell

NCT04649983 2023-04-18

CD19 and CD22 Targeted CAR-T Cell Therapy for Relapsed/Refractory B Cell Leukemia and Lymphoma

Leukemia, B-Cell, Lymphoma, B-Cell

NCT05503355 2023-04-04

A Phase I/II Dose Escalation and Expansion Study of BST-236 Plus Venetoclax in Patients With Unfit Newly Diagnosed AML

80 enrolled

Leukemia, Myeloid, Acute

NCT05448599 2023-03-15

A Clinical Study of 6MW3211 Monotherapy or Combination Therapy for AML or MDS

120 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05429905 2023-03-09

Dual Anti-CD22/CD19 Chimeric Antigen Receptor-directed T Cells (CART2219.1) for Relapsed Refractory B-Lineage Leukaemia

48 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03467256 2023-02-24

CD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALL

18 enrolled

Burkitt Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04669067 2023-02-17

TL-895 and KRT-232 Study in Acute Myeloid Leukemia

18 enrolled

Leukemia, Myeloid, Acute

NCT05672420 2023-01-05

Umbilical Cord Derived Mesenchymal Stem Cells for Treatment-induced Myelosuppression in Hematologic Malignancies

Classical hematologyLymphoidOther hematologic neoplasmPlasma cell

181 enrolled

Anemia, Hemorrhage, Infections, Leukemia, Lymphoma, Multiple Myeloma, Neutropenia, Thrombocytopenia, Hematologic Neoplasms

NCT05497310 2022-10-26

Effectiveness and Safety of Therapy Based on Attenuated ATO Plus Low-Dose ATRA in Patients With APL

15 enrolled

Leukemia, Promyelocytic, Acute

NCT05587088 2022-10-19

PA001

GastrointestinalLymphoidOther hematologic neoplasm

82 enrolled

Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03825367 2022-10-12

Nivolumab in Combination With 5-azacytidine in Childhood Relapsed/Refractory AML

13 enrolled

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT04687761 2022-09-08

Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old

84 enrolled

Leukemia, Myeloid, Acute

NCT04502394 2022-08-04

Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL

84 enrolled

Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse

NCT05488132 2022-08-04

Administration of Anti-siglec-6 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia (rr/AML)

Leukemia, Myeloid, Acute

NCT04632316 2022-06-21

A Trial to Evaluate the Safety and Efficacy of oNKord® in Subjects With Acute Myeloid Leukemia

33 enrolled

Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT04082910 2022-04-13

Metoprolol Treatment for Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells

30 enrolled

Cytokine Release Syndrome, Hematologic Neoplasms

NCT05309213 2022-04-04

Clinical Trial to Evaluate the Safety and Efficacy of IM19 CAR-T Cells in Patients With Relapsed and Refractory (R/R) B-cell Acute Lymphoblastic Leukemia

58 enrolled

Burkitt Lymphoma, Leukemia

NCT04764513 2022-03-28

Safety and Efficiency of γδ T Cell Against Hematological Malignancies After Allo-HSCT

LymphoidMyeloidOther hematologic neoplasm

Lymphoma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05250362 2022-03-15

Ex Vivo Expanded NK Cells Infusion Decrease Relapse Post Hematopoietic Stem Cell Transplantation

56 enrolled

Recurrence, Hematologic Neoplasms

NCT04112589 2022-03-14

A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First Treatment

63 enrolled

Leukemia, Myeloid, Acute

NCT05023707 2021-12-30

Anti-FLT3 CAR T-cell Therapy in FLT3 Positive Relapsed/Refractory Acute Myeloid Leukemia

5 enrolled

Leukemia, Myeloid, Acute

NCT03821519 2021-12-23

Haplo-CIK

Hematologic Neoplasms

NCT05164042 2021-12-20

CAR-T

Leukemia

NCT05100303 2021-10-29

A Study to Evaluate the Tolerance and Efficacy of Mitoxantrone Hydrochloride Liposome Injection Combined With Cytarabine in Patients With Acute Myeloid Leukemia (AML)

58 enrolled

Recurrence, Leukemia, Myeloid, Acute

NCT05066958 2021-10-04

Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT

LymphoidMyeloidOther hematologic neoplasm

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Virus Diseases, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05061147 2021-10-01

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Max-40279-01 in Combination With Azacitidine (AZA) in Patients With Myelodysplastic Syndrome (MDS) or Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)

100 enrolled

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT04622956 2021-09-14

GVHD Prophylaxis With Methotrexate in Haploidentical HCT Using Posttransplant Cyclophosphamide

47 enrolled

Graft vs Host Disease, Hematologic Neoplasms

NCT05028478 2021-08-31

A Study of CN202 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors or Hematologic Malignancies

164 enrolled

Neoplasm Metastasis, Hematologic Neoplasms

NCT04946890 2021-07-01

A Study of MRX2843 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia

104 enrolled

Leukemia, Myeloid, Acute

NCT04762485 2021-06-02

Humanized CD7 CAR T-cell Therapy for r/r CD7+ Acute Leukemia

Lymphoma, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute

NCT04884984 2021-05-13

Anti-CLL1 CAR T-cell Therapy in CLL1 Positive Relapsed/Refractory Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

NCT04790747 2021-03-10

Sequential Radiotherapy With CAR-T Cells in the Treatment of Relapsed and Refractory Hematological Malignancies With Extramedullary Lesions

50 enrolled

Recurrence, Hematologic Neoplasms

NCT04747093 2021-02-10

Induced-T Cell Like NK Cells for B Cell Malignancies

12 enrolled

Burkitt Lymphoma, Leukemia, B-Cell, Lymphoma, B-Cell

NCT03262298 2021-02-09

Anti-CD22 CAR-T Cell Therapy Targeting B Cell Malignancies