Clinical Trials

Phase 2/3 Not yet recruiting

Leukemia, Myeloid, Acute

NCT07440290 2026-02-27

DETERMINE

CNSEndocrineGastrointestinalGynecologicHead & NeckLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Glioma, Histiocytosis, Langerhans-Cell, Laryngeal Neoplasms, Lymphoproliferative Disorders, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT04708054 2026-02-19

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

MyeloidOther hematologic neoplasm

324 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT04817761 2026-02-18

SPARK-ALL: Calaspargase Pegol in Adults With ALL

42 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT06860269 2026-02-10

GRAALL-2024

1,200 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07366801 2026-01-26

Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies

64 enrolled

Recurrence, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03701308 2026-01-21

Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy

267 enrolled 11 charts

Leukemia, Myeloid, Acute

NCT03870750 2026-01-12

Identifying Best Approach in Improving Quality of Life and Survival After a Donor Stem Cell Transplant in Older, Medically Infirm, or Frail Patients With Blood Diseases

458 enrolled

Hematologic Neoplasms

NCT06788756 2025-12-16

L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

312 enrolled

Leukemia, Myeloid, Acute

NCT01046825 2025-12-10

Mature B-Cell Lymphoma And Leukemia Study III

128 enrolled 12 charts

Leukemia, Lymphoma, Lymphoma, Non-Hodgkin

NCT03117751 2025-12-05

Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma

790 enrolled

Phase 2/3 Not yet recruiting

Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT07264010 2025-12-04

Sorafenib Combined With Venetoclax as Pre-emptive Therapy Strategy for MRD+ AML: a Prospective, Single-arm, Multicenter Clinical Study

87 enrolled

Leukemia, Myeloid, Acute, Neoplasm, Residual

NCT05722886 2025-11-24

DETERMINE

825 enrolled

Lymphoproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Hematologic Neoplasms

NCT05768178 2025-11-24

DETERMINE

CNSDermatologicEndocrineGastrointestinalGynecologicHead & NeckMyeloidOther hematologic neoplasmPlasma cellThoracic

Thyroid Cancer, Papillary, Carcinoma, Non-Small-Cell Lung, Glioma, Laryngeal Neoplasms, Melanoma, Multiple Myeloma, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Ovarian Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms, Erdheim-Chester Disease, Thyroid Carcinoma, Anaplastic

NCT06378138 2025-11-21

ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (APEX-03)

226 enrolled

Hematologic Neoplasms

NCT07202052 2025-10-07

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT)

900 enrolled

Infections, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Neoplasms, Neoplasms, Plasma Cell

NCT07202065 2025-10-07

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Dosing Immunoglobulin (Dose Ig)

900 enrolled

Infections, Leukemia, Lymphoma, Neoplasms, Neoplasms, Plasma Cell

NCT07202078 2025-10-07

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Starting Immunoglobulin (Start Ig)

900 enrolled

Infections, Leukemia, Lymphoma, Neoplasms, Neoplasms, Plasma Cell

NCT06855810 2025-08-26

CCCG-TALL-2025

610 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT06882057 2025-08-26

CCCG-LR-B-ALL

3,000 enrolled

Burkitt Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04851717 2025-07-01

Investigation of Remimazolam in Children Undergoing Sedation for Medical Procedures

100 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT05356169 2025-05-30

Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid Leukemia

312 enrolled

Leukemia, Myeloid, Acute

NCT03937544 2025-05-29

Intravenous Autologous CD19 CAR-T Cells for R/R B-ALL

10 enrolled

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

NCT02600208 2025-02-19

Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies with Alpha Beta TCell and B Cell Depletion Using the CliniMACS Device

60 enrolled

Hematologic Neoplasms

NCT00179829 2025-02-04

WT1 for the Detection of Minimal Residual Disease

LymphoidMyeloidOther hematologic neoplasm

50 enrolled

Leukemia, Neoplasms, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03092674 2025-01-16

Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

MyeloidOther hematologic neoplasm

76 enrolled 16 charts

GATA2 Deficiency, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT06756152 2025-01-01

Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis

LymphoidMyeloidOther hematologic neoplasm

50 enrolled

Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myelomonocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01228331 2024-12-11

Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL

745 enrolled

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06475820 2024-08-23

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosis

LymphoidMyeloidOther hematologic neoplasm

150 enrolled

Graft vs Host Disease, Lymphoma, Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02131753 2024-08-22

Therapy Optimisation for the Treatment of Hairy Cell Leukemia

210 enrolled

Phase 2/3 Enrolling by invitation

Leukemia, Hairy Cell

NCT06544109 2024-08-09

Ven APL

98 enrolled

Leukemia, Promyelocytic, Acute

NCT02416388 2024-08-07

BIG-1

3,100 enrolled

Leukemia, Myeloid, Acute

NCT01751997 2024-04-19

Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors

116 enrolled

Leukemia, Myeloid, Acute

NCT03801525 2024-04-19

ULTRA-V

277 enrolled 19 charts

Leukemia, Lymphocytic, Chronic, B-Cell

NCT05678621 2024-04-19

RATIONALISE

300 enrolled

Agammaglobulinemia, Infections, Leukemia, Lymphoma, Neoplasms, Hematologic Neoplasms, Neoplasms, Plasma Cell

NCT05939180 2024-04-09

VA vs DA for Newly Diagnosed Hig-risk AML

116 enrolled

Leukemia, Myeloid, Acute

NCT06285136 2024-02-29

Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult

40 enrolled

Leukemia, Myeloid, Acute

NCT02473146 2024-02-02

ALFA1401

225 enrolled

Leukemia, Myeloid, Acute

NCT06238336 2024-02-02

Clinical Study of CAR-T Technology for the Treatment of Relapsed Refractory Malignant Haematological Tumours

Hematologic Neoplasms

NCT01949129 2024-01-16

Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

1,800 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04257175 2023-11-28

CAR-T CD19 for Acute Myelogenous Leukemia With t 8:21 and CD19 Expression

10 enrolled

Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute

NCT04145531 2023-11-18

An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)

229 enrolled 17 charts 2 FDA

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03699475 2023-09-29

THRIVE

MyeloidOther hematologic neoplasm

1 enrolled 9 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01428635 2023-09-26

Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy

Classical hematologyMyeloidOther hematologic neoplasm

21 enrolled 10 charts

Blast Crisis, Thrombocytopenia, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Primary Myelofibrosis

NCT00413439 2023-05-10

Safety, Efficacy and Pharmacokinetics of an Antifungal in Patients Undergoing Chemotherapy

18 enrolled

Leukemia, Myeloid, Acute

NCT04217278 2023-05-10

COSI

333 enrolled

Leukemia, Myeloid, Acute

NCT05805098 2023-04-07

VHA

60 enrolled

Leukemia, Myeloid, Acute

NCT02634294 2023-03-16

Peg Interferon α-2b for Relapsed Hematological Malignancies After Allo-HSCT

Graft vs Host Disease, Recurrence, Hematologic Neoplasms

NCT00354120 2023-03-10

GLOBAL