Clinical Trials

26 enrolled 14 charts

Advanced Solid Tumor

NCT04381650 2025-12-10

A Study of TAK-981 Given With Pembrolizumab in Participants With Select Advanced or Metastatic Solid Tumors

161 enrolled 44 charts

Advanced or Metastatic Solid Tumors

NCT05147272 2025-12-05

Study of RP-6306 With Gemcitabine in Advanced Solid Tumors

67 enrolled 22 charts

Adult Solid Tumor

NCT05147350 2025-12-05

MINOTAUR

38 enrolled 17 charts

Advanced Solid Tumor

NCT06232408 2025-11-21

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

29 enrolled 15 charts

385 enrolled 17 charts 2 FDA

Advanced Solid Tumor

NCT02060188 2025-11-06

CheckMate142

Phase 2 Completed

GastrointestinalOther solid neoplasm

Microsatellite Unstable Colorectal Cancer

NCT03770494 2025-11-04

A Study of LY3405105 in Participants With Advanced Cancer

54 enrolled 26 charts

Solid Tumor

NCT04972110 2025-10-30

ATTACC

156 enrolled 19 charts

Advanced Solid Tumor, Adult

NCT02597036 2025-10-23

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

62 enrolled 25 charts

Solid Tumors

NCT04497116 2025-10-21

TRESR

276 enrolled 33 charts

Advanced Solid Tumor

NCT05976334 2025-10-06

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

3 enrolled 19 charts

Other solid neoplasmThoracic

Solid Tumors

NCT04914897 2025-10-02

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)

Phase 2 Terminated

106 enrolled 21 charts

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT04319198 2025-09-30

Rollover Study in Participants With Metastatic Solid Tumors Benefiting From Therapy With Sacituzumab Govitecan-hziy

Phase 4 Completed

25 enrolled 15 charts

Metastatic Solid Tumors

NCT05072106 2025-09-16

Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors

11 enrolled 26 charts

Advanced Solid Tumor

NCT03195478 2025-09-15

A Study of Nivolumab in Combination With Ipilimumab in Chinese Participants With Previously Treated Advanced or Recurrent Solid Tumors

37 enrolled 32 charts

Solid Tumor

NCT05063318 2025-09-02

Clinical Trial of Lurbinectedin (PM01183) in Patients With Advanced Solid Tumors

14 enrolled 20 charts

Advanced Solid Tumors

NCT04047862 2025-08-22

Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors

446 enrolled 49 charts

Locally Advanced and Metastatic Solid Tumors

NCT05109442 2025-08-20

Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers

112 enrolled 28 charts

Advanced Solid Tumor

NCT03126110 2025-08-14

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

145 enrolled 47 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Neoplasm Metastasis, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02903914 2025-08-05

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

GastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

260 enrolled 52 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Head and Neck Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms

NCT04380753 2025-07-23

AMG 510 Ethnic Sensitivity Study (CodeBreaK 105).

Phase 1 Active not recruiting

12 enrolled 12 charts

Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation

NCT03853109 2025-07-20

AMG 404 in Patients With Advanced Solid Tumors

171 enrolled 24 charts

Advanced Solid Tumors

NCT04153565 2025-07-17

MK-3475-A17

Other solid neoplasmThoracic

19 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma

NCT04259450 2025-07-17

Study to Assess AFM24 in Advanced Solid Cancers

85 enrolled 35 charts

Advanced Solid Tumor

NCT04455620 2025-07-02

BNT151 as a Monotherapy and in Combination With Other Anti-cancer Agents in Patients With Solid Tumors

49 enrolled 19 charts

Solid Tumor

NCT04642365 2025-05-21

A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.

49 enrolled 31 charts

Phase 3 Active not recruiting

Solid Tumors

NCT03710876 2025-05-20

INFINITE

53 enrolled 23 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT04827576 2025-05-08

ELEVATELung&UC

Phase 2 Terminated

106 enrolled 22 charts

Solid Tumor

NCT02913313 2025-04-20

A Study of BMS-986207 Given Alone and in Combination With Nivolumab or With Nivolumab and Ipilimumab in Advanced Solid Tumors

101 enrolled 34 charts

Broad Solid Tumor

NCT04084366 2025-03-26

Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors

44 enrolled 15 charts

Locally Advanced Solid Tumor

NCT04716634 2025-03-25

Efficacy and Safety of Tislelizumab in Combination With Fruquintinib in Participants With Selected Solid Tumors

Phase 2 Completed

84 enrolled 17 charts

Advanced Solid Tumors

NCT04882917 2025-03-07

First-in-human Study of M4076 in Advanced Solid Tumors (DDRiver Solid Tumors 410)

22 enrolled 17 charts

Advanced Solid Tumors

NCT04608045 2025-03-03

Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors

9 enrolled 7 charts

Advanced Solid Tumor

NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

42 enrolled 39 charts

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

NCT03593226 2025-02-14

Study to Evaluate Safety & Tolerability of AGI-134 in Solid Tumour

38 enrolled 13 charts

Superficial, Palpable, Unresectable/Metastatic Solid Tumour

NCT06469138 2025-01-29

8479217

CNSDermatologicGastrointestinalMyeloidOther hematologic neoplasmOther solid neoplasmThoracic

6 enrolled 17 charts

Mesothelioma, Malignant, COVID-19, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Melanoma, Myelodysplastic Syndromes, Pancreatic Neoplasms, Leukemia, Myeloid, Acute

NCT04074759 2025-01-23

FPT155-001

80 enrolled 49 charts

Advanced Solid Tumors

NCT02240238 2025-01-22

Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer

119 enrolled 24 charts

Solid Tumors

NCT04622774 2025-01-15

First-in-Human Study of IMGC936 in Participants With Advanced Solid Tumors

56 enrolled 21 charts

Advanced Solid Tumor

NCT03854227 2025-01-13

A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors

54 enrolled 42 charts

Advanced Solid Tumors

NCT05382936 2025-01-09

Study of the PI3K Inhibitor SL-901 in Patients With Advanced Solid Tumors

20 enrolled 14 charts

Advanced Solid Tumor

NCT03477175 2025-01-07

Study to Assess the Long-term Safety of Lenvatinib Monotherapy, a Lenvatinib Combination Regimen, or a Comparator Treatment Arm to Cancer Participants in Eisai Sponsored Lenvatinib Trials

Phase 2 Completed

40 enrolled 13 charts

Solid Tumors

NCT04727554 2025-01-06

Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors

11 enrolled 27 charts

Advanced Solid Tumors

NCT01928394 2024-12-27

A Study of Nivolumab by Itself or Nivolumab Combined With Ipilimumab in Patients With Advanced or Metastatic Solid Tumors

1,163 enrolled 33 charts 1 FDA

Advanced or Metastatic Solid Tumors

NCT03717415 2024-12-27

A Study of Rebastinib (DCC-2036) in Combination With Carboplatin in Patients With Advanced or Metastatic Solid Tumors