Clinical Trials

Phase 1/2 Active not recruiting

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT02535312 2026-03-18

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

30 enrolled 15 charts

Mesothelioma, Malignant

NCT06097728 2026-03-04

eVOLVE-Meso

Phase 3 Recruiting

825 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT05083481 2026-02-27

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

Phase 1/2 Recruiting

366 enrolled

Phase 2 Not yet recruiting

Advanced Solid Tumors

NCT07415031 2026-02-17

A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies

170 enrolled

Solid Tumors

NCT05067283 2026-02-12

KANDLELIT-001

Phase 1 Recruiting

830 enrolled

Advanced Solid Tumors

NCT06783647 2026-02-12

A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]

Phase 2 Recruiting

230 enrolled

Phase 2 Not yet recruiting

Advanced Solid Tumour

NCT07234058 2026-02-11

LAG-MAPS

126 enrolled

Mesothelioma, Malignant

NCT02662504 2026-02-05

MesoPDT

6 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT05136677 2026-01-23

CheckMate 6DW

102 enrolled

Mesothelioma, Malignant

NCT04334759 2026-01-22

DREAM3R

Phase 3 Completed

214 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT06741644 2026-01-09

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

Phase 1/2 Recruiting

660 enrolled

Advanced Solid Tumors

NCT03760575 2025-12-04

Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

Phase 1 Recruiting

20 enrolled

Phase 1 Active not recruiting

Mesothelioma, Malignant

NCT03228537 2025-11-10

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

28 enrolled 17 charts

Phase 1 Active not recruiting

Mesothelioma, Malignant

NCT04185883 2025-10-22

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

610 enrolled

Other solid neoplasmSarcoma

Advanced Solid Tumors

NCT06385678 2025-09-19

A Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Phase 1/2 Active not recruiting

47 enrolled

Phase 1 Active not recruiting

Advanced KRAS G12D Mutant Solid Tumors

NCT04162015 2025-09-12

A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma

22 enrolled

Phase 1/2 Not yet recruiting

Mesothelioma, Malignant

NCT07157956 2025-09-05

CVL006-T1002

318 enrolled

Advanced Solid Tumor

NCT04047862 2025-08-22

Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors

446 enrolled 49 charts

Locally Advanced and Metastatic Solid Tumors

NCT06057935 2025-07-22

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

Phase 2 Recruiting

64 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT04153565 2025-07-17

MK-3475-A17

19 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma

NCT06318286 2025-05-25

PENINSULA

Phase 2 Recruiting

25 enrolled

Mesothelioma, Malignant

NCT04158141 2025-02-19

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Phase 3 Terminated

16 enrolled 18 charts

Mesothelioma, Malignant, Mesothelioma

NCT03656549 2024-12-17

IMPROVE-I

Phase 4 Completed

6 enrolled

520 enrolled 16 charts 1 FDA

Carcinoma, Non-Small-Cell Lung, Mesothelioma

NCT02784171 2024-12-10

Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma

Phase 2/3 Completed

Phase NA Not yet recruiting

Mesothelioma

NCT06649448 2024-10-18

EF-001

200 enrolled

Solid Tumor Cancer

NCT02707666 2024-07-31

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

Phase 1 Terminated

7 enrolled

Mesothelioma, Malignant

NCT03319537 2024-05-23

Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma

Phase 1/2 Terminated

9 enrolled 9 charts

605 enrolled 17 charts 2 FDA

Mesothelioma

NCT02899299 2024-05-21

CheckMate743

Phase 3 Completed

Mesothelioma

NCT06116240 2023-11-03

A Clinical Trial of TQB2450 Injection Combined With AL2846 Capsules in Patients With Advanced Solid Tumors

Phase 1 Unknown

135 enrolled

Solid Tumor

NCT00101283 2023-07-03

Pemetrexed Plus Gemcitabine or Carboplatin for Patients With Advanced Malignant Pleural Mesothelioma

32 enrolled 8 charts

Mesothelioma, Malignant, Mesothelioma

NCT05794477 2023-06-02

A Study of SHR-1802 in Combination With Adebrelimab in Patients With Advanced Solid Tumors

Phase 1/2 Unknown

132 enrolled

Advanced Solid Tumor

NCT02436733 2022-11-07

Pleurectomy/ Decortication (P/D) Preceded or Followed by Chemotherapy in Patients With Early Stage MPM

Phase 2 Unknown

64 enrolled

Mesothelioma, Malignant

NCT00738582 2022-09-22

Amatuximab

89 enrolled 12 charts

Mesothelioma, Malignant

NCT03023319 2022-06-14

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

GenitourinaryGynecologicOther solid neoplasmThoracic

6 enrolled

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Mesothelioma, Ovarian Neoplasms, Thymoma, Thymus Neoplasms

NCT04173338 2022-06-14

Cabozantinib With Pemetrexed in Advanced Non-small Cell Lung Cancer, Urothelial Cancer and Malignant Mesothelioma

Phase 1 Terminated

9 enrolled

GenitourinaryOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell

NCT03655821 2022-05-13

IMPROVE-II

Phase 4 Terminated

81 enrolled

Carcinoma, Non-Small-Cell Lung, Mesothelioma

NCT03655834 2022-05-10

IMPROVE-III

Phase 4 Completed

10 enrolled

Carcinoma, Non-Small-Cell Lung, Mesothelioma

NCT02347917 2022-04-12

A Study of BBI608 in Combination With Pemetrexed and Cisplatin in Adult Patients With Malignant Pleural Mesothelioma

Phase 1/2 Completed

28 enrolled 23 charts

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT01655225 2022-04-08

A Study of LY3023414 in Participants With Advanced Cancer

BreastLymphoidOther solid neoplasmThoracic

156 enrolled

Mesothelioma, Malignant, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lymphoma, Lymphoma, Non-Hodgkin, Mesothelioma, Neoplasm Metastasis

NCT02838745 2022-03-31

Study of Cytoreductive Surgery and Hyperthermic Intraoperative Chemotherapy With Pemetrexed and Cisplatin for MPM

Phase 1 Terminated

7 enrolled

Mesothelioma

NCT01085630 2021-08-18

Pemetrexed Disodium/Observation in Treating Patients W/ Malignant Pleural Mesothelioma w/Out Progressive Disease After 1st Line Chemotherapy

72 enrolled 12 charts

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT00700336 2021-07-20

Study of CBP501 + Pemetrexed + Cisplatin on MPM (Phase I/II)

Phase 1/2 Completed

69 enrolled 9 charts

Mesothelioma, Malignant

NCT04713761 2021-01-26

Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural Mesothelioma

Phase 2 Unknown

15 enrolled

Mesothelioma, Malignant

NCT00295503 2020-10-20

Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma

53 enrolled 8 charts

Mesothelioma

NCT01675765 2020-09-30

Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma

60 enrolled 15 charts

Mesothelioma, Malignant, Neoplasms

NCT00859495 2020-08-25

Trimodal Lung-Sparing Treatment of Pleural Mesothelioma

Phase 2 Terminated

9 enrolled 4 charts

Mesothelioma, Malignant

NCT03920839 2020-04-24

INCMGA00012 Plus Chemotherapy in Participants With Advanced Solid Tumors (POD1UM-105)

Phase 1 Withdrawn

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT02357147 2020-03-17

ARTEMIS

Phase 2 Terminated

124 enrolled 10 charts

Severe combined immunodeficiency with sensitivity to ionizing radiation, Mesothelioma, Malignant

NCT00334594 2019-05-15

Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma

153 enrolled