Clinical Trials Browser

Phase 1 × Topotecan × Other solid neoplasm × Clear all

NCT05521984 2025-12-08

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Phase 1 Recruiting

20 enrolled

Other solid neoplasm

Pediatric Brain Tumor

NCT03987685 2022-02-16

Evaluate Oral Topotecan With HM30181A Monotherapy in Patients With Advanced Malignancies

Phase 1 Completed

10 enrolled

Other solid neoplasm

Solid Tumor

NCT02390843 2020-04-03

AflacST1402

Phase 1 Completed

13 enrolled

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

Carcinoma, Renal Cell, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Rhabdoid Tumor

NCT00003194 2019-04-05

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Solid Tumors

Phase 1 Terminated

24 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00732420 2017-11-13

Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors

Phase 1 Completed

68 enrolled

Other solid neoplasm

Solid Tumours

NCT00541359 2017-08-09

Bortezomib and Topotecan Hydrochloride in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

54 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00682279 2015-04-17

A Phase I Study Of Oral Topotecan And Lapatinib In Subjects With Advanced Solid Tumors

Phase 1 Withdrawn

Other solid neoplasm

Advanced Solid Tumors

NCT00002948 2014-07-02

High-Dose Topotecan and Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Phase 1 Terminated

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00002587 2013-06-03

Paclitaxel Plus Topotecan in Treating Patients With Solid Tumors

Phase 1 Completed

20 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00068484 2013-02-01

A Dose Finding Phase I Trial of the Combination of Topotecan and PS-341, a Novel Proteasome Inhibitor, in Advanced Malignancies

Phase 1 Completed

25 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00005990 2012-11-09

R115777 Plus Topotecan in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00502892 2012-08-01

Topotecan, Ifosfamide and Carboplatin in Children and Young Adults With Solid Tumors

Phase 1 Completed

2 enrolled

Other solid neoplasm

Solid Tumors

NCT00516438 2010-12-08

Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Topotecan

Phase 1 Completed

48 enrolled

Other solid neoplasm

Malignant Solid Tumors

NCT00460876 2008-05-02

Phase I Trial of Periocular Topotecan in Retinoblastoma

Phase 1 Completed

5 enrolled

Other solid neoplasm

Retinoblastoma