Clinical Trials Browser

Interventional × fludarabine × Other solid neoplasm × Clear all

NCT06885697 2026-02-17

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Phase 1 Recruiting

GastrointestinalGynecologicOther solid neoplasmThoracic

Colonic Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms

NCT06598371 2026-02-11

A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors

Phase 1/2 Recruiting

Other solid neoplasm

Select Advanced Solid Tumors

NCT06556108 2026-01-20

ALPP CAR-T Cells for ALPP-Positive Advanced Solid Tumors

Phase 1/2 Completed

Other solid neoplasm

Advanced Solid Tumors

NCT06241456 2025-12-09

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumor

NCT06066424 2025-10-14

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT06027983 2025-09-23

Chimeric Receptor T Cells With Trastuzumab in HER2+ Advanced Breast Cancer and Other Solid Tumors

Phase 1/2 Not yet recruiting

BreastOther solid neoplasm

HER2+ Advanced Breast Cancer

NCT03907852 2025-08-27

Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer

Phase 1/2 Active not recruiting

GastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Mesothelioma, Ovarian Neoplasms, Cholangiocarcinoma

NCT05451849 2025-08-27

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

Phase 1/2 Active not recruiting

BreastGastrointestinalGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Mesothelioma, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma, Triple Negative Breast Neoplasms

NCT02498912 2025-07-31

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT05881525 2025-07-16

NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumors

NCT03935893 2025-07-10

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Phase 2 Recruiting

DermatologicEndocrineGastrointestinalNETOther solid neoplasmSarcomaThoracic

Turcot syndrome, Mesothelioma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Neuroendocrine Tumors, Microsatellite Instability

NCT07010523 2025-06-08

Anti-Mesothelin CAR-T Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors

Phase NA Recruiting

Other solid neoplasm

Mesothelin-positive Advanced Malignant Solid Tumors

NCT04643574 2025-02-14

NeoTIL in Advanced Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumor, Adult

NCT06773091 2025-02-11

NKSOLID

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumors

NCT05693844 2024-05-10

Pan-T Booster Co-expressing MSLN CAR T Cell Therapy in Advanced/Metastatic Solid Tumors

Phase 1/2 Recruiting

Other solid neoplasm

Advanced or Metastatic Solid Tumors

NCT06394622 2024-05-01

A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor

NCT06101082 2024-03-06

A Clinical Study Evaluating the Safety and Efficacy of Anti-HER2-CAR-T Cells Injection in Patients With Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor

NCT06277804 2024-02-26

A Phase I Study of LTC004 Combin With FC in Patients With Advanced/Metastatic Malignancies Tumor

Phase 1 Not yet recruiting

Other solid neoplasm

Adult Solid Tumor

NCT05681650 2023-12-12

HER2 Targeted HypoSti.CAR-T Cells in HER2 Positive Advanced Solid Tumors

Phase 1/2 Recruiting

Other solid neoplasm

HER2 Positive Advanced Solid Tumors

NCT03139370 2023-08-25

Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers

Phase 1 Terminated

Other solid neoplasm

Solid Tumor

NCT05531708 2023-03-01

Exploratory Study of Novel MSLN CAR-T Cell Therapy in Patients With MSLN-positive Advanced Refractory Solid Tumors

Phase 1 Withdrawn

Other solid neoplasm

Mesothelin-positive Advanced Refractory Solid Tumors

NCT05648994 2022-12-13

TCR-T Cells for the Treatment NY-ESO-1-positive Advanced Solid Tumors

Phase EARLY_PHASE1 Not yet recruiting

Other solid neoplasm

Solid Tumors

NCT05515185 2022-08-25

B7-H3 Targeting CAR-T Cells Therapy for B7-H3 Positive Solid Tumors

Phase EARLY_PHASE1 Unknown

Other solid neoplasm

Advanced Solid Tumor

NCT03992326 2021-03-18

Adoptive Transfer Of Autologous Tumor-Infiltrating Lymphocytes in Solid Tumors

Phase 1 Terminated

Other solid neoplasm

Solid Tumor, Adult

NCT02638428 2020-03-19

Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy

Phase 2 Unknown

Other solid neoplasm

Relapsed Pediatric Solid Tumor

NCT01583686 2019-10-14

CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer

Phase 1/2 Terminated

15 enrolled 14 charts

GastrointestinalGynecologicOther solid neoplasmThoracic

Uterine Cervical Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms

NCT03171220 2017-06-06

NRT-01

Phase 1/2 Unknown

Other solid neoplasm

Advanced Malignant Solid Tumor