Clinical Trials Browser

Phase 1 × Other solid neoplasm × Clear all

NCT04491942 2026-03-19

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Phase 1 Active not recruiting

BreastGenitourinaryGynecologicOther solid neoplasmThoracic

Mesothelioma, Malignant, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Penile Neoplasms, Triple Negative Breast Neoplasms

NCT06589596 2026-03-19

An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumor

NCT01434316 2026-03-18

Veliparib and Dinaciclib in Treating Patients With Advanced Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Advanced Malignant Solid Neoplasm

NCT02453620 2026-03-18

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Phase 1 Active not recruiting

BreastOther solid neoplasm

Anatomic Stage III Breast Cancer AJCC v8

NCT04158336 2026-03-18

A Study of Azenosertib (ZN-c3) in Participants With Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT06233942 2026-03-18

Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumor

NCT06248411 2026-03-18

A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced or Metastatic Solid Tumors

NCT06487858 2026-03-18

A Study of BGB-R046 as Monotherapy and in Combination With Tislelizumab in Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumor

NCT06585488 2026-03-18

A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification

Phase 1 Recruiting

GastrointestinalOther solid neoplasmThoracic

Metastatic Solid Tumors

NCT07480681 2026-03-18

Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HLX97 (a KAT6A/B Inhibitor) in Patients With Advanced/Metastatic Solid Tumor

Phase 1 Not yet recruiting

Other solid neoplasm

Advanced/Metastatic Solid Tumors

NCT05155332 2026-03-17

A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT06056024 2026-03-17

A Study to Test How Well Different Doses of BI 3706674 Are Tolerated by People With Advanced Cancer in the Stomach and Oesophagus

Phase 1 Completed

Other solid neoplasm

Solid Tumor, KRAS Mutation

NCT06927297 2026-03-17

Phase I Study of the Safety, Tolerability, and Efficacy of an Engineered Mitochondrial Vaccine in Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumor Malignancies

NCT06960395 2026-03-17

Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor Malignancies

NCT07477743 2026-03-17

A Phase Ib Clinical Study on the Safety and Efficacy of HC010 Combinations in Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumor Cancer

NCT07475559 2026-03-16

JSKN016HC in Patients With Advanced or Metastatic Solid Malignant Tumors

Phase 1 Not yet recruiting

Other solid neoplasm

Advanced Solid Tumor Malignancies

NCT05571839 2026-03-13

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Phase 1 Active not recruiting

DermatologicGastrointestinalOther solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Mesothelioma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT05957536 2026-03-13

A Study of D3L-001 as Monotherapy in Subjects With HER2-Positive Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

HER-2 Positive Advanced Solid Tumors

NCT06307795 2026-03-13

A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Locally Advanced or Metastatic Solid Tumors

NCT06391918 2026-03-13

Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors

Phase 1 Terminated

Other solid neoplasm

Solid Tumor, Adult

NCT06892379 2026-03-13

A Study of HS-20110 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumors

NCT07207707 2026-03-13

A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor Malignancies

NCT07223125 2026-03-13

A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced-stage Solid Tumors

NCT07469982 2026-03-13

A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors

Phase 1 Not yet recruiting

Other solid neoplasm

Advanced or Metastatic Solid Tumors With Homozygous MTAP Deletion

NCT04897022 2026-03-12

A Study of Pembrolizumab and Radiation Therapy in People With Mesothelioma

Phase 1 Active not recruiting

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT05238792 2026-03-12

Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor

NCT06563375 2026-03-12

Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor

NCT06598800 2026-03-12

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumor

NCT07372625 2026-03-12

A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

Phase 1 Recruiting

Other solid neoplasm

TP53 Y220C Mutation

NCT07467629 2026-03-12

QLS5212 for Participants With Advanced Solid Tumors

Phase 1 Not yet recruiting

Other solid neoplasm

Solid Tumor Cancer

NCT04261413 2026-03-11

Phase Ia/Ib Study of RS-0139 in Patients With a Recurrent, Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT06234397 2026-03-11

Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced or Metastatic Solid Tumors

NCT05735366 2026-03-10

A Phase 1 Study of SAIL66 in Patients With CLDN6-positive Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT05781048 2026-03-10

A Phase I Clinical Study of the Safety， Tolerability，Pharmacokinetics, and Initial Efficacy of HRS-6209 Monotherapy in Patients With Advanced Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Advanced Solid Tumors

NCT07462442 2026-03-10

Study of QLS5308 in Patients With Advanced Solid Tumors

Phase 1 Not yet recruiting

Other solid neoplasm

Metastatic Solid Tumors

NCT05514132 2026-03-09

A Study to Evaluate the Safety and Pharmacokinetics of Ceralasertib in Combination With Durvalumab in Chinese Patients With Advanced Solid Tumours

Phase 1 Active not recruiting

Other solid neoplasm

Advanced Solid Tumours

NCT07141706 2026-03-09

A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced/Metastatic Solid Tumors

NCT02959463 2026-03-06

Pembrolizumab After Radiation Therapy in Treating Patients With Pleural Malignant Mesothelioma

Phase 1 Active not recruiting

24 enrolled 11 charts

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT05661201 2026-03-06

NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor

NCT06031441 2026-03-06

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Locally Advanced Solid Tumors

NCT07189949 2026-03-06

A Study of HRS-2329 in Participants With Advanced Solid Tumors Harboring RAS Mutations or Amplifications

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumors Harboring RAS Mutations or Amplifications

NCT04928508 2026-03-05

Okgyn1

Phase 1 Recruiting

Other solid neoplasm

Solid Tumor, Adult

NCT06596473 2026-03-05

A Study of BG-C477 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumors

NCT03313778 2026-03-04

KEYNOTE-603

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumors

NCT05981703 2026-03-04

A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumor

NCT07387068 2026-03-04

Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumors

NCT03207672 2026-03-03

Study of E7389 Liposomal Formulation in Participants With Solid Tumor

Phase 1 Active not recruiting

Other solid neoplasm

Solid Tumor

NCT03420963 2026-03-03

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Phase 1 Terminated

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT05873686 2026-03-03

A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

Phase 1 Recruiting

GenitourinaryOther solid neoplasmThoracic

Adenocarcinoma, Carcinoma, Carcinoma, Non-Small-Cell Lung, Kidney Neoplasms, Mesothelioma, Neoplasms

NCT06057038 2026-03-03

A Safety Trial of GEN1042 in Japanese Subjects With Malignant Solid Tumors

Phase 1 Active not recruiting

Other solid neoplasm

Malignant Solid Tumor