Clinical Trials Browser

Parkinson Disease 4, Autosomal Dominant Lewy Body, Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Head and Neck Neoplasms, Lung Neoplasms, Mesothelioma, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms

NCT04257110 2025-07-24

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

Phase 1 Completed

117 enrolled

Other solid neoplasm

Locally Advanced/Metastatic HER2 Positive Solid Tumors

NCT03853109 2025-07-20

AMG 404 in Patients With Advanced Solid Tumors

Phase 1 Completed

171 enrolled 24 charts

Other solid neoplasm

Advanced Solid Tumors

NCT04501770 2025-07-20

A Study of M802 (HER2 and CD3) in HER2-Positive Advanced Solid Tumors

Phase 1 Completed

34 enrolled

Other solid neoplasm

HER2-Positive Solid Tumors

NCT06255665 2025-07-20

A Study of JNJ-79032421 Targeting Mesothelin for Advanced Stage Solid Tumors

Phase 1 Completed

35 enrolled

Other solid neoplasm

Advanced Stage Solid Tumors

NCT04153565 2025-07-17

MK-3475-A17

Phase 1 Completed

19 enrolled 14 charts

Other solid neoplasmThoracic

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma

NCT04242199 2025-07-14

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Phase 1 Completed

182 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Nasopharyngeal Carcinoma, Esophageal Squamous Cell Carcinoma, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Mesothelioma, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma

NCT01286896 2025-07-10

Use of Individual Pharmacokinetically (PK)-Guided Sunitinib Dosing: A Feasibility Study in Patients With Advanced Solid Tumors

Phase 1 Completed

43 enrolled

Other solid neoplasm

Malignant Solid Tumour

NCT05323045 2025-07-09

A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate BYON3521

Phase 1 Completed

31 enrolled

Other solid neoplasm

Solid Tumor

NCT05487235 2025-07-03

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

57 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT05383703 2025-07-02

MNC-168

Phase 1 Completed

12 enrolled

Other solid neoplasm

Advanced Malignant Solid Tumors

NCT03990233 2025-06-26

A Trial of BI 765063 Monotherapy and in Combination With BI 754091 in Patients With Advanced Solid Tumours

Phase 1 Completed

100 enrolled

Other solid neoplasm

Solid Tumor, Adult

NCT04525859 2025-06-24

Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma

Phase 1 Completed

19 enrolled

Other solid neoplasmThoracic

Mesothelioma, Malignant

NCT06007482 2025-06-23

A Study of ES009 in Subjects With Locally Advanced or Metastatic Solid Tumors

Phase 1 Completed

12 enrolled

Other solid neoplasm

Advanced Solid Tumor

Clinical Trials

A Study of Azenosertib (ZN-c3) in Participants With Solid Tumors

A Study to Test How Well Different Doses of BI 3706674 Are Tolerated by People With Advanced Cancer in the Stomach and Oesophagus

Phase Ia/Ib Study of RS-0139 in Patients With a Recurrent, Locally Advanced or Metastatic Solid Tumors

A Phase 1 Study of SAIL66 in Patients With CLDN6-positive Locally Advanced or Metastatic Solid Tumors

Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors

A Study to Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer

Assessment of Safety, Tolerability and PK Profile of MSP008-22 in Patients With Advanced Solid Tumours

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

PEMBIB

A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors

A Phase 1b/2 Study of ADG116, ADG116 Combined With Anti-PD-1 Antibody or Anti-CD137 Antibody in Solid Tumors Patients

A Study of RC108-ADC in Subjects With Advanced Malignant Solid Tumors

Study of ZGGS15 in Patients With Advanced Solid Tumors

RAPIRI

A Study of NB003 in Patients With Advanced Malignancies

A Phase 1 Study of RO7623066 Alone and in Combination in Patients With Advanced Solid Tumors

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors

Assessment of Safety and Preliminary Efficacy With BAT6026 in Solid Tumor Patients in China

Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT1308 in Advanced Solid Tumors

A Study of KL340399 in Patients With Advanced Solid Tumors

A Study of Intratumoral KL340399 in Patients With Advanced Solid Tumors

A Study of BR101 Injection Alone in Subjects With Advanced Solid Tumors

Study of AMG 256 in Adult Subjects With Advanced Solid Tumors

Combination of Serabelisib and Insulin Suppressing Diet With or Without Nab-paclitaxel in Subjects With Advanced Solid Tumors With PIK3CA Mutations

Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors

A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects

An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fed Condition

A Study of SHR-A1811 in Subjects With Advanced Malignant Solid Tumors

Clinical Trial of Lurbinectedin (PM01183) in Patients With Advanced Solid Tumors

EPRAD

Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors

First-In-Human Study in Subjects With Advanced or Metastatic Solid Malignant Tumors

UTAA06 Injection for Treatment of Advanced Malignant Solid Tumors

A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors

MEDI5752 in Japanese Patients With Advanced Solid Tumors.

A Study of Axl Inhibitor FC084CSA in Patients With Advanced Malignant Solid Tumors

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors

AMG 404 in Patients With Advanced Solid Tumors

A Study of M802 (HER2 and CD3) in HER2-Positive Advanced Solid Tumors

A Study of JNJ-79032421 Targeting Mesothelin for Advanced Stage Solid Tumors

MK-3475-A17

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Use of Individual Pharmacokinetically (PK)-Guided Sunitinib Dosing: A Feasibility Study in Patients With Advanced Solid Tumors

A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate BYON3521

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

MNC-168

A Trial of BI 765063 Monotherapy and in Combination With BI 754091 in Patients With Advanced Solid Tumours

Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma

A Study of ES009 in Subjects With Locally Advanced or Metastatic Solid Tumors