Clinical Trials

Glioblastoma, Gliosarcoma

NCT03478462 2026-03-18

CLOVER-2

CNSGenitourinaryLymphoidSarcoma

30 enrolled

Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Glioma, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04817254 2026-03-18

Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

47 enrolled

Phase NA Active not recruiting

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT03115333 2026-03-02

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

146 enrolled

Glioblastoma, Gliosarcoma

NCT02455557 2026-02-25

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

66 enrolled 11 charts

Phase 3 Active not recruiting

Glioblastoma, Gliosarcoma

NCT05095376 2026-02-17

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

265 enrolled

Glioblastoma, Gliosarcoma

NCT04216329 2026-01-23

Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

11 enrolled 19 charts

Phase EARLY_PHASE1 Active not recruiting

Glioblastoma, Gliosarcoma

NCT05091866 2026-01-07

Natural Progesterone for the Treatment of Recurrent Glioblastoma

4 enrolled

Glioblastoma, Gliosarcoma

NCT02192359 2025-11-14

Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas

18 enrolled 16 charts

Phase 1/2 Active not recruiting

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT06521567 2025-11-12

A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

83 enrolled

CNSDermatologicGastrointestinalLymphoidSarcoma

Fibrolamellar hepatocellular carcinoma, Diffuse Intrinsic Pontine Glioma, Ependymoma, Glioblastoma, Carcinoma, Hepatocellular, Hodgkin Disease, Melanoma, Rhabdomyosarcoma, Osteosarcoma, Hepatoblastoma

NCT02062827 2025-10-02

M032-HSV-1

29 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Virus Diseases, Gliosarcoma

NCT02337686 2025-08-15

Pembrolizumab in Treating Patients With Recurrent Glioblastoma

18 enrolled 12 charts

Glioblastoma, Gliosarcoma

NCT06614855 2025-08-06

A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma

12 enrolled

Phase 1/2 Active not recruiting

Astrocytoma, Glioblastoma, Gliosarcoma

NCT04528680 2025-07-31

SC9/ABX

57 enrolled

Glioblastoma, Gliosarcoma

NCT04521686 2025-06-27

Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

200 enrolled

Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Glioblastoma, Glioma, Melanoma, Prostatic Neoplasms, Thyroid Neoplasms, Central Nervous System Neoplasms, Cholangiocarcinoma

NCT03197506 2025-04-06

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

52 enrolled

Glioblastoma, Gliosarcoma

NCT01903330 2025-03-05

ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

84 enrolled

Glioblastoma, Gliosarcoma

NCT00102648 2024-10-17

Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide

34 enrolled