Clinical Trials

103 enrolled

Neoplasms, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT05152472 2026-01-08

ATEZOGIST

Phase 2 Recruiting

110 enrolled

Neoplasms, Gastrointestinal Stromal Tumors

NCT06333314 2025-12-02

Pan-MSI-ACSE

Phase 2 Recruiting

120 enrolled

EndocrineSarcoma

Neoplasm Metastasis, Neoplasms, Sarcoma, Adrenocortical Carcinoma, Carcinoma, Neuroendocrine

NCT02576431 2025-11-12

NAVIGATE

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

215 enrolled 3 FDA

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT04095208 2025-10-02

CONGRATS

67 enrolled

Tertiary Lymphoid Structures, Neoplasm Metastasis, Neoplasms, Sarcoma

NCT03709680 2025-01-14

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

128 enrolled

Diffuse Intrinsic Pontine Glioma, Bone Neoplasms, Medulloblastoma, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Rhabdoid Tumor

NCT03678883 2024-11-07

9-ING-41 in Patients with Advanced Cancers

BreastCNSGastrointestinalGenitourinaryLymphoidOther hematologic neoplasmSarcomaThoracic

350 enrolled

Bone Neoplasms, Breast Neoplasms, Glioma, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Neoplasm Metastasis, Neoplasms, Hereditary Sensory and Autonomic Neuropathies, Pancreatic Neoplasms, Sarcoma, Colorectal Neoplasms, Leukemia-Lymphoma, Adult T-Cell

NCT03556384 2024-11-04

Temozolomide (TMZ) in Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

23 enrolled

Hematoma, Subdural, Neoplasms, Gastrointestinal Stromal Tumors

NCT01863745 2024-08-19

Nilotinib Roll-over Protocol for Patients in Novartis-sponsored Nilotinib Study and Benefiting From Nilotinib Treatment

15 enrolled 7 charts

CNSGenitourinaryLymphoidSarcoma

Neoplasms, Gastrointestinal Stromal Tumors

NCT02624388 2024-05-06

UVA-Gen001

Phase 2 Terminated

4 enrolled 16 charts

Brain Neoplasms, Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Medulloblastoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Neuroectodermal Tumors, Primitive

NCT03349450 2023-11-02

SPiReL

25 enrolled

LymphoidSarcoma

Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Recurrence, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Dendritic Cell Sarcoma, Interdigitating

NCT00019968 2023-10-31

Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg

Neoplasms, Sarcoma, Muscle Neoplasms

NCT02034110 2023-08-21

Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers

206 enrolled 40 charts 2 FDA

CNSEndocrineGastrointestinalHead & NeckOther hematologic neoplasmPlasma cellSarcoma

Nonseminomatous germ cell tumor, Biliary Tract Neoplasms, Glioma, Leukemia, Hairy Cell, Multiple Myeloma, Neoplasms, Gastrointestinal Stromal Tumors, Thyroid Carcinoma, Anaplastic

NCT02992743 2023-04-11

Letetresgene Autoleucel Engineered T Cells in NY-ESO-1 Positive Participants With Advanced Myxoid/ Round Cell Liposarcoma

23 enrolled 25 charts

Neoplasms, Liposarcoma, Myxoid

NCT03275818 2022-06-07

ABRADES

69 enrolled

Neoplasms, Recurrence, Sarcoma, Sarcoma, Ewing, Desmoid Tumors, Desmoplastic Small Round Cell Tumor

NCT03570437 2022-03-02

COPELIA

Phase 2 Unknown

124 enrolled

GynecologicSarcoma

Carcinosarcoma, Neoplasms, Endometrial Neoplasms

NCT02798406 2021-07-15

CAPTIVE

49 enrolled

Brain Neoplasms, Disease, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue, Nervous System Diseases, Neuroectodermal Tumors, Neoplasms, Neuroepithelial, Gliosarcoma

NCT02423863 2020-12-17

Poly-ICLC

DermatologicHead & NeckSarcoma

26 enrolled

Head and Neck Neoplasms, Melanoma, Neoplasms, Sarcoma

NCT01848457 2020-03-16

Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy

13 enrolled 15 charts

Ototoxicity, Neoplasms, Osteosarcoma

NCT01498328 2020-02-17

ReACT

127 enrolled

Brain Neoplasms, Glioblastoma, Neoplasms, Recurrence, Gliosarcoma

NCT03697824 2019-10-29

Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a

Phase 2 Withdrawn

Neoplasms, Sarcoma, Synovial

NCT00107003 2018-07-05

GW572016 to Treat Recurrent Malignant Brain Tumors

9 enrolled

BreastCNSGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Gliosarcoma

NCT00617929 2017-12-28

Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant

Phase 2 Terminated

12 enrolled 12 charts

Pdgfra-Associated Chronic Eosinophilic Leukemia, Carcinoma, Ovarian Epithelial, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Primary Myelofibrosis

NCT00405327 2017-11-06

A Pilot Study of Tumor Cell Vaccine for High-risk Solid Tumor Patients Following Stem Cell Transplantation

16 enrolled

CNSGenitourinarySarcoma

Neoplasms, Wilms Tumor, Neuroblastoma, Sarcoma

NCT00055237 2017-09-06

Bevacizumab to Treat Kaposi's Sarcoma in HIV-Positive and HIV-Negative Patients

19 enrolled 10 charts

Neoplasms, Sarcoma, Kaposi, HIV Infections

NCT01404650 2016-10-04

Study of Hsp90 Inhibitor AUY922 for the Treatment of Patients With Refractory Gastrointestinal Stromal Tumor

25 enrolled 9 charts

Neoplasms, Gastrointestinal Stromal Tumors

NCT00587964 2016-02-22

Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

51 enrolled 6 charts

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Testicular Neoplasms

NCT00060944 2014-09-08

A Study to Assess Treatment With 2 Different Dosing Schedules of Trabectidin Administered to Patients With Advanced Cancer

271 enrolled 13 charts

Leiomyosarcoma, Liposarcoma, Neoplasm Metastasis, Neoplasms

NCT00786838 2014-04-11

A Study to Assess the Potential Effects of a Single-Dose Administration of Trabectedin on the QT Intervals of the Electrocardiogram

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcomaThoracic

76 enrolled 17 charts

BreastGynecologicSarcoma

Breast Neoplasms, Neoplasms, Ovarian Neoplasms, Sarcoma

NCT00637637 2013-08-12

External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases

Phase 2 Unknown

60 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Thyroid Cancer, Papillary, Anus Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Hodgkin Disease, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mouth Neoplasms, Mycosis Fungoides, Nasopharyngeal Neoplasms, Neoplasms, Wilms Tumor, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Parathyroid Neoplasms, Penile Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sezary Syndrome, Stomach Neoplasms, Tongue Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Esthesioneuroblastoma, Olfactory, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Histiocytoma, Malignant Fibrous, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT01095926 2013-06-28

Doxo

CNSGenitourinaryLymphoidOther hematologic neoplasmSarcoma

101 enrolled

Neoplasms, Wilms Tumor, Neuroblastoma, Sarcoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Cardiotoxicity

NCT00385203 2012-07-16

The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).

35 enrolled 13 charts

Neoplasms, Sarcoma, Gastrointestinal Stromal Tumors

NCT00357084 2010-09-14

Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell Transplant

DermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

53 enrolled

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Carcinoma, Ovarian Epithelial, Blast Crisis, Burkitt Lymphoma, Graft vs Host Disease, Hodgkin Disease, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Myeloproliferative Disorders, Neoplasms, Wilms Tumor, Recurrence, Sezary Syndrome, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis

NCT00002673 2010-06-17

Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation

BreastCNSDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

30 enrolled

Teratoma, Testicular, Teratoma, Ovarian, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Infections, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Teratoma, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis

NCT00001189 2008-03-04

The Treatment of Grade I Sarcomas and Benign, Non-Metastasizing Highly Invasive Soft Tissue Tumors

150 enrolled