Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Phase 1/2 Terminated
53 enrolled 22 charts
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer
Phase 2 Terminated
9 enrolled 11 charts
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Phase 1 Terminated
79 enrolled 24 charts
Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Paediatric Participants With Solid Tumors (SCOOP)
Phase 1 Terminated
47 enrolled 43 charts
A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors
Phase 1 Terminated
94 enrolled 28 charts
PROACT
Phase 2 Terminated
49 enrolled 12 charts
Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults
Phase 2 Terminated
1 enrolled 7 charts
SUNRISELMS
Phase 2/3 Terminated
359 enrolled 15 charts
Open-Label Study of the CDK4/6 Inhibitor SPH4336 in Subjects With Locally Advanced or Metastatic Liposarcomas
Phase 2 Terminated
14 enrolled 8 charts
Tranexamic Acid in Radical Resection and Endoprosthetic Reconstruction
Phase 4 Terminated
12 enrolled 6 charts
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors
Phase 1/2 Terminated
87 enrolled 29 charts
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors
Phase 2 Terminated
54 enrolled 11 charts
PLX3397
Phase 1/2 Terminated
39 enrolled 13 charts
STIR
Phase 2 Terminated
15 enrolled 11 charts
TK216 in Patients With Relapsed or Refractory Ewing Sarcoma
Phase 1/2 Terminated
85 enrolled 18 charts
Vaccine Therapy With Bevacizumab Versus Bevacizumab Alone in Treating Patients With Recurrent Glioblastoma Multiforme That Can Be Removed by Surgery
Phase 2 Terminated
90 enrolled 13 charts
MANTRA
Phase 3 Terminated
175 enrolled 16 charts
A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma
Phase 1 Terminated
9 enrolled 10 charts
Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure
Phase 3 Terminated
15 enrolled 13 charts
TTI-621-03
Phase 2 Terminated
76 enrolled 53 charts
Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors
Phase 1 Terminated
12 enrolled 12 charts
Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Phase 1 Terminated
5 enrolled 16 charts
Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer
Phase 1 Terminated
7 enrolled 19 charts
BRAF
Phase 2 Terminated
5 enrolled 15 charts
QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors
Phase 1/2 Terminated
89 enrolled 20 charts
Pazopanib Maintenance Phase II
Phase 2 Terminated
1 enrolled 4 charts
Palbociclib + Ganitumab In Ewing Sarcoma
Phase 2 Terminated
10 enrolled 15 charts
NT-I7 for Kaposi Sarcoma in Patients With or Without HIV
Phase 1 Terminated
8 enrolled 14 charts
Advanced Gastrointestinal Endoscopic Imaging
Phase NA Terminated
3 enrolled 6 charts
Epacadostat and Pembrolizumab in Patients With GIST
Phase 2 Terminated
1 enrolled 1 chart
A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
Phase 1/2 Terminated
32 enrolled 20 charts
QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma
Phase 2 Terminated
8 enrolled 10 charts
UVA-Gen001
Phase 2 Terminated
4 enrolled 16 charts
Study of PF-07263689 in Participants With Selected Advanced Solid Tumors
Phase 1 Terminated
13 enrolled 16 charts
A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma
Phase 2 Terminated
99 enrolled 10 charts
DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST)
Phase 1 Terminated
34 enrolled 27 charts
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies
Phase 1/2 Terminated
79 enrolled 22 charts
Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.
Phase 1 Terminated
14 enrolled 20 charts
ATX-101
Phase 2 Terminated
4 enrolled 12 charts
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Phase 1/2 Terminated
31 enrolled 17 charts
Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma
Phase 1 Terminated
4 enrolled 6 charts
18F-FTC-146 PET/CT in Newly-Diagnosed Osteosarcoma
Phase 2 Terminated
1 enrolled 5 charts
LODESTAR
Phase 2 Terminated
83 enrolled 16 charts
Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancers
Phase 1/2 Terminated
12 enrolled 15 charts
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma
Phase 1/2 Terminated
23 enrolled 15 charts
Durvalumab and Standard Chemotherapy Before Surgery in Treating Patients With Variant Histology Bladder Cancer
Phase 2 Terminated
7 enrolled 9 charts
Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With Uterine Cancer
Phase NA Terminated
14 enrolled 5 charts
ALpha-T
Phase 2 Terminated
1 enrolled 5 charts
Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
Phase 1/2 Terminated
7 enrolled 9 charts
AXL1717
Phase 1/2 Terminated
10 enrolled 8 charts