Clinical Trials Browser

Desmoid Tumors

NCT04693377 2025-10-27

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT05949099 2025-09-08

Study of Cryoablation and Nirogacestat for Desmoid Tumor

Phase 2 Recruiting

28 enrolled

Sarcoma

Desmoid Tumors

NCT05302921 2025-01-01

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Phase 2 Completed

5 enrolled

CNSDermatologicGastrointestinalGenitourinarySarcoma

Carcinoma, Hepatocellular, Melanoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT04118166 2023-12-12

Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma

Phase 2 Completed

30 enrolled 9 charts

Sarcoma

NCT01461252 2021-07-16

Safety and Efficacy of Cryoablation Combined With Radiation Therapy for the Palliation of Painful Bone Metastases

Phase 1 Withdrawn

Sarcoma

Bone Neoplasms, Neoplasm Metastasis, Pain

NCT01461265 2021-07-16

Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases

Phase 1 Completed

29 enrolled

Sarcoma

Bone Neoplasms, Neoplasm Metastasis, Pain

NCT01065441 2020-01-22

Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer

Phase 1/2 Completed

9 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Melanoma, Ovarian Neoplasms, Prostatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT02849366 2019-09-12

Combination of Cryosurgery and NK Immunotherapy for Recurrent Sarcoma

Phase 1/2 Completed

30 enrolled

Sarcoma

NCT00499733 2019-01-18

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Phase EARLY_PHASE1 Terminated

19 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Osteosarcoma, Tongue Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Intraocular Lymphoma

NCT01986829 2018-09-19

Cryoablation, Radiofrequency Ablation, or Microwave Ablation in Treating Patients With Metastatic Sarcoma Stable on Chemotherapy

Phase 2 Terminated

9 enrolled 13 charts

Sarcoma

Sarcoma, Osteosarcoma

NCT00002863 2014-05-22

Cryosurgery in Treating Patients With Soft Tissue Sarcoma

Phase 1 Terminated

19 enrolled

Sarcoma

Clinical Trials

CRYODESMO-02

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Study of Cryoablation and Nirogacestat for Desmoid Tumor

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma

Safety and Efficacy of Cryoablation Combined With Radiation Therapy for the Palliation of Painful Bone Metastases

Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases

Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer

Combination of Cryosurgery and NK Immunotherapy for Recurrent Sarcoma

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

Cryoablation, Radiofrequency Ablation, or Microwave Ablation in Treating Patients With Metastatic Sarcoma Stable on Chemotherapy

Cryosurgery in Treating Patients With Soft Tissue Sarcoma