Clinical Trials Browser

Neoplasms, Germ Cell and Embryonal, Ovarian Neoplasms, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Carcinoma, Neuroendocrine, Lymphoma, Extranodal NK-T-Cell

NCT03056001 2023-11-18

Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma

Phase 2 Completed

30 enrolled 22 charts

Sarcoma

NCT03349450 2023-11-02

SPiReL

Phase 2 Completed

25 enrolled

LymphoidSarcoma

Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Recurrence, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Dendritic Cell Sarcoma, Interdigitating

NCT03063632 2023-10-25

Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma

Phase 2 Completed

28 enrolled 15 charts

LymphoidSarcoma

Mycosis Fungoides, Sezary Syndrome, Sarcoma, Synovial, Liposarcoma, Myxoid

NCT05961761 2023-07-27

PROPANE

Phase 2 Recruiting

80 enrolled

Sarcoma

Hemangiosarcoma, Sarcoma, Histiocytoma, Malignant Fibrous

NCT02798406 2021-07-15

CAPTIVE

Phase 2 Completed

49 enrolled

CNSSarcoma

Brain Neoplasms, Disease, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue, Nervous System Diseases, Neuroectodermal Tumors, Neoplasms, Neuroepithelial, Gliosarcoma

NCT02691026 2021-06-23

A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery

Phase 2 Terminated

8 enrolled

Sarcoma

Neurofibrosarcoma

NCT02423863 2020-12-17

Poly-ICLC

Phase 2 Completed

26 enrolled

DermatologicHead & NeckSarcoma

Head and Neck Neoplasms, Melanoma, Neoplasms, Sarcoma

NCT03013127 2020-10-14

PROMO

Phase 2 Terminated

12 enrolled

Sarcoma

Osteosarcoma

NCT02301039 2020-09-29

SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas

Phase 2 Completed

144 enrolled 16 charts

Sarcoma

Bone Neoplasms, Sarcoma

NCT03697824 2019-10-29

Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a

Phase 2 Withdrawn

Sarcoma

Neoplasms, Sarcoma, Synovial

NCT03469804 2019-10-21

KAPKEY

Phase 2 Unknown

17 enrolled

Sarcoma

Sarcoma, Kaposi, Disease Progression

Clinical Trials

Intratumoral Vusolimogene Oderparepvec (VO) in Combination With Pembrolizumab for Angiosarcoma

I-SPY

Pembrolizumab in Neoplasms or Lymphomas

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

PULSAR

Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent Glioblastoma

EFTISARC-NEO

NeoSarc

A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas

A Study of Pembrolizumab and Olaparib in People With Endometrial Cancer or Endometrial Carcinosarcoma

Pembrolizumab in Treating Patients With Recurrent Glioblastoma

Pazopanib With or Without Pembrolizumab for Metastatic Soft Tissue Sarcoma

A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

SOC-2320

Pembrolizumab and Pemetrexed for Progressive Chordoma

Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas

Epacadostat and Pembrolizumab in Patients With GIST

AcSé

Safety, Tolerability, and Efficacy of Doxorubicin and Pembrolizumab for Sarcoma

SPiReL

Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma

PROPANE

CAPTIVE

A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery

Poly-ICLC

PROMO

SARC028: A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas

Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a

KAPKEY