Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma
Phase 2/3 Completed
159 enrolled 17 charts
NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
Phase 1 Completed
16 enrolled
Sunitinib or Cediranib for Alveolar Soft Part Sarcoma
Phase 2 Completed
34 enrolled 22 charts
Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma
Phase 1 Completed
12 enrolled 12 charts
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Phase 1 Completed
17 enrolled
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
Phase 1 Completed
10 enrolled
Endoxifen in Adults With Hormone Receptor Positive Solid Tumors
Phase 1 Completed
40 enrolled
Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab
Phase 2 Completed
35 enrolled 13 charts
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
Completed
19,522 enrolled
Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma
Phase 2 Completed
53 enrolled 17 charts
Nivolumab Alone or in Combination With Ipilimumab in Treating Patients With Advanced Uterine Leiomyosarcoma
Phase 2 Completed
20 enrolled 11 charts
Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
20 enrolled 12 charts
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
18 enrolled 12 charts
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
4 enrolled 12 charts
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
6 enrolled 12 charts
Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
Phase 1 Completed
29 enrolled
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)
Phase 2 Completed
23 enrolled 11 charts
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
Phase 1 Completed
58 enrolled 17 charts
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
Phase 1 Completed
15 enrolled
Studies of Human Herpesvirus 8 and Kaposi's Sarcoma in Sicily
Completed
4,622 enrolled
Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma
Phase 1/2 Completed
Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
Phase 1 Completed
Vaccine Therapy in Treating Patients With Metastatic Cancer
Phase 1 Completed
Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis
Phase 2 Completed
17 enrolled 14 charts
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas
Phase 1 Completed
46 enrolled 20 charts
Cabozantinib for Adults With Advanced Soft Tissue Sarcoma
Phase 2 Completed
55 enrolled 16 charts
Isolated Limb Perfusion of Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Soft Tissue Sarcoma of the Arm or Leg
Phase 2 Completed
Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma
Phase 2 Completed
41 enrolled 15 charts
Testing the Combination of Two Experimental Drugs MK-3475 (Pembrolizumab) and Interferon-gamma for the Treatment of Mycosis Fungoides and Sézary Syndrome and Advanced Synovial Sarcoma
Phase 2 Completed
28 enrolled 15 charts
Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas
Phase 1/2 Completed
140 enrolled 23 charts
Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery
Phase 2 Completed
164 enrolled 22 charts
Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Phase 1/2 Completed
76 enrolled 25 charts
Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers
Phase NA Completed
10 enrolled 16 charts
Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis
Phase 3 Completed
87 enrolled 14 charts
Cediranib, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Phase 1/2 Completed
46 enrolled
Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma
Phase 1 Completed
32 enrolled
Pomalidomide for Kaposi Sarcoma in People With or Without HIV
Phase 1/2 Completed
28 enrolled 23 charts
Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 1/2 Completed
125 enrolled 12 charts
Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma
Phase 2 Completed
261 enrolled 10 charts
Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors
Phase 2 Completed
137 enrolled 13 charts
Pazopanib and ARQ 197 for Advanced Solid Tumors
Phase 1 Completed
32 enrolled 21 charts
Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma
Phase 1/2 Completed
38 enrolled 11 charts
Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma
Phase 2 Completed
22 enrolled 15 charts
CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma
Phase 1/2 Completed
43 enrolled 19 charts
A Study of Chemotherapy Plus Azidothymidine in the Treatment of Kaposi's Sarcoma in Patients With AIDS
Phase 1 Completed
36 enrolled
A Study of Doxorubicin in the Treatment of AIDS-Related Kaposi's Sarcoma
Phase 2 Completed
48 enrolled
A Study of AZT Plus Human Interferon Alpha in the Treatment of AIDS-Related Kaposi's Sarcoma
Phase 1 Completed
48 enrolled
Phase I Study of Weekly Oral VP-16 for AIDS-Associated Kaposi's Sarcoma
Phase 1 Completed
24 enrolled
A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcoma
Phase 1 Completed
24 enrolled
Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's Sarcoma
Phase 2 Completed
60 enrolled