Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma
Phase 1/2 Terminated
53 enrolled 22 charts
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer
Phase 2 Terminated
9 enrolled 11 charts
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Phase 1 Terminated
79 enrolled 24 charts
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer
Phase 1 Terminated
32 enrolled
Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastoma
Phase 1 Terminated
40 enrolled
Sunitinib in Sarcomas of the Central Nervous System
Phase 2 Terminated
5 enrolled 14 charts
Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma
Phase 1/2 Terminated
14 enrolled 17 charts
Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases
Phase 1/2 Terminated
3 enrolled 10 charts
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients With Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum
Phase 1/2 Terminated
21 enrolled 11 charts
Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas
Phase 1 Terminated
10 enrolled
Tumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or Mediastinum
Phase 1 Terminated
19 enrolled
Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer
Phase 1 Terminated
39 enrolled
HGS-ETR2 to Treat Children With Solid Tumors
Phase 1 Terminated
30 enrolled
BAY 43-9006 (Sorafenib) to Treat Patients With Kaposi's Sarcoma
Phase 1 Terminated
10 enrolled
Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols
Terminated
767 enrolled
Tumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor Removal
Phase 1 Terminated
41 enrolled
Ganetespib and Ziv-Aflibercept in Refractory Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas
Phase 1 Terminated
5 enrolled 15 charts
Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma
Phase 1/2 Terminated
8 enrolled 20 charts
18F-Fluoromisonidazole and Fludeoxyglucose F 18 PET/CT Patients With Soft Tissue Sarcoma
Phase 2 Terminated
8 enrolled 4 charts
S0502
Phase 3 Terminated
12 enrolled 13 charts
Cilengitide in Treating Patients Who Are Undergoing Surgery for Recurrent or Progressive Glioblastoma Multiforme
Phase 2 Terminated
30 enrolled 10 charts
Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive Glioblastoma
Phase 2 Terminated
47 enrolled 9 charts
O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy
Phase 2 Terminated
12 enrolled 10 charts
Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the Brain
Phase 2 Terminated
1 enrolled 7 charts
Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus
Phase 2 Terminated
8 enrolled 6 charts
RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma
Phase 1/2 Terminated
13 enrolled 13 charts
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
Phase 2 Terminated
100 enrolled
Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme
Phase 1 Terminated
41 enrolled
BMS-247550 in Treating Patients With Advanced Soft Tissue Sarcoma
Phase 2 Terminated
26 enrolled
Comparison of Two Different Doses of STI571 in Treating Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumor
Phase 3 Terminated
748 enrolled
Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia
Phase 1 Terminated
129 enrolled
Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia
Phase 1 Terminated
22 enrolled
Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma
Phase 1 Terminated
40 enrolled
Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
Phase 2 Terminated
82 enrolled
Oblimersen and Imatinib Mesylate in Treating Patients With Advanced Gastrointestinal Stromal Tumors That Cannot Be Removed By Surgery
Phase 2 Terminated
96 enrolled
EMD 121974 in Treating Patients With HIV-Related Kaposi's Sarcoma
Phase 1 Terminated
30 enrolled
RO4929097 in Treating Patients With Recurrent Invasive Gliomas
Phase 1 Terminated
22 enrolled
Bortezomib in Treating Patients With Recurrent Glioma
Phase 1 Terminated
42 enrolled
Radiolabeled Monoclonal Antibody With or Without Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Lymphoma
Phase 1 Terminated
36 enrolled
EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer
Phase NA Terminated
30 enrolled
Use of EF5 to Measure the Oxygen Level in Tumor Cells of Patients Undergoing Surgery or Biopsy for Newly Diagnosed Supratentorial Malignant Glioma
Phase NA Terminated
48 enrolled
EF5 to Evaluate Tumor Hypoxia in Patients With High-Grade Soft Tissue Sarcoma or Mouth Cancer
Phase NA Terminated
120 enrolled