Clinical Trials

377 enrolled

Phase EARLY_PHASE1 Recruiting

Sarcoma, Neuroaxonal Dystrophies

NCT07048249 2026-03-18

Single Arm Romiplostim to Prevent CIT

26 enrolled

Sarcoma, Ewing

NCT07479732 2026-03-18

Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma

56 enrolled

Osteosarcoma

NCT06898970 2026-03-17

Intratumoral Vusolimogene Oderparepvec (VO) in Combination With Pembrolizumab for Angiosarcoma

18 enrolled

Hemangiosarcoma

NCT06934889 2026-03-17

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

60 enrolled

Glioblastoma, Gliosarcoma

NCT07470008 2026-03-17

Prospective Registry of Histotripsy for Soft Tissue Tumors

200 enrolled

Sarcoma, Soft Tissue Neoplasms

NCT07477457 2026-03-17

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

45 enrolled

Neoplasm Metastasis, Osteosarcoma

NCT05051059 2026-03-16

QOLSarcoma

60 enrolled

Bone Neoplasms, Sarcoma

NCT05950594 2026-03-16

IVIM & OLINK in Sarcoma

145 enrolled

NCT06384404 2026-03-16

UFSR for OS

10 enrolled

Osteosarcoma

NCT07194044 2026-03-16

METTSEO

15 enrolled

Sarcoma, Ewing

NCT01042379 2026-03-13

I-SPY

5,000 enrolled

BreastSarcoma

Pathologic Complete Response, Breast Neoplasms, Hemangiosarcoma, Neoplasms, Triple Negative Breast Neoplasms

NCT01804634 2026-03-13

Reduced Intensity Haploidentical BMT for High Risk Solid Tumors

CNSGastrointestinalSarcoma

60 enrolled

Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT06843967 2026-03-13

A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma

54 enrolled

Liposarcoma, Liposarcoma, Myxoid

NCT05269381 2026-03-12

PNeoVCA

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

132 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT06349642 2026-03-12

ELEPHAS-04

DermatologicGastrointestinalGenitourinaryGynecologicSarcomaThoracic

324 enrolled

Clear-cell metastatic renal cell carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinosarcoma, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Neoplasm Metastasis, Skin Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05019703 2026-03-11

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

40 enrolled

Osteosarcoma

NCT06625190 2026-03-11

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

27 enrolled

Chordoma, Myoepithelioma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Nerve Sheath Neoplasms, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT02701153 2026-03-10

Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

51 enrolled

NCT04219202 2026-03-10

Neurofibrosarcoma

NCT03896568 2026-03-05

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

36 enrolled

Astrocytoma, Glioblastoma, Glioma, Gliosarcoma

NCT05672108 2026-03-05

Phase II Trial of Lung Chemoemobolization

GastrointestinalSarcomaThoracic

30 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Mediastinal Neoplasms, Pleural Neoplasms, Sarcoma

NCT07291297 2026-03-05

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

50 enrolled

NCT03442465 2026-03-04

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

300 enrolled

Bone Neoplasms, Chondrosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT06815666 2026-03-04

BAL Fluid Biomarkers in Sarcoma

70 enrolled

NCT01772771 2026-03-03

Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program

CNSDermatologicOther hematologic neoplasmSarcoma

12,000 enrolled

Glioma, Melanoma, Sarcoma, Hematologic Neoplasms

NCT07447050 2026-03-03

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

BreastGastrointestinalGynecologicHead & NeckSarcomaThoracic

24 enrolled

Breast Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Sarcoma, Stomach Neoplasms, Urogenital Neoplasms, Colorectal Neoplasms

NCT04771520 2026-03-02

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

DermatologicGastrointestinalSarcomaThoracic

50 enrolled

Lung Neoplasms, Melanoma, Neoplasm Metastasis, Sarcoma, Colorectal Neoplasms

NCT06492954 2026-03-02

AflacST2301

12 enrolled

Osteosarcoma

NCT06541262 2026-03-02

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

104 enrolled

Liposarcoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT07144254 2026-03-02

Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma

24 enrolled

Osteosarcoma

NCT06474676 2026-02-27

T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

40 enrolled

NCT07193550 2026-02-27

A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)

70 enrolled

Bone Neoplasms

NCT05225428 2026-02-25

VERDI

BreastDermatologicGastrointestinalGenitourinaryGynecologicSarcoma

1,020 enrolled

Breast Neoplasms, Kidney Neoplasms, Melanoma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Colorectal Neoplasms

NCT06308419 2026-02-25

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

18 enrolled

Leiomyosarcoma, Sarcoma

NCT07432932 2026-02-25

PANTHR-S

800 enrolled

Hemangiosarcoma, Leiomyosarcoma, Liposarcoma, Sarcoma

NCT05918640 2026-02-23

LiFFT

63 enrolled

Neoplasms, Sarcoma, Ewing, Desmoplastic Small Round Cell Tumor

NCT04354064 2026-02-20

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

100 enrolled

Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT04719156 2026-02-20

ICGTM

110 enrolled

NCT06709495 2026-02-19

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

63 enrolled

Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoplastic Small Round Cell Tumor

NCT07071727 2026-02-19

SCOPES II

150 enrolled

NCT06715579 2026-02-18

CAIR

500 enrolled

Hemangiosarcoma

NCT07359911 2026-02-18

ACTIVE-SARC

40 enrolled

NCT07410676 2026-02-18

EBNK-ST-001

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicOther hematologic neoplasmSarcomaThoracic

83 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Bronchogenic, Disease, Esophageal Neoplasms, Glioblastoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms

NCT03911388 2026-02-17

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

24 enrolled

Choroid Plexus Carcinoma, Astrocytoma, Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Cerebellar Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neoplasm Metastasis, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Glandular and Epithelial, Neoplasms, Nerve Tissue, Nervous System Diseases, Nervous System Neoplasms, Oligodendroglioma, Virus Diseases, Central Nervous System Neoplasms, Neuroectodermal Tumors, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Gliosarcoma, Rhabdoid Tumor

NCT04055220 2026-02-17

REGOSTA

168 enrolled

Pathologic Complete Response, Bone Neoplasms, Chondrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Patient Compliance, Sarcoma, Ewing, Osteosarcoma, Histiocytoma, Malignant Fibrous

NCT04698785 2026-02-17

REGOMAIN

36 enrolled