Clinical Trials

56 enrolled

BreastCNSGastrointestinalGenitourinaryHead & NeckThoracic

Brain Neoplasms, Lung Neoplasms

NCT04075305 2026-03-05

MOMENTUM

Recruiting

8,000 enrolled

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Esophageal Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Radiation Injuries, Rectal Neoplasms

NCT05538130 2026-03-04

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

CNSDermatologicHead & NeckThoracic

124 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioma, Melanoma, Neoplasms, Thyroid Neoplasms

NCT06047379 2026-03-02

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

134 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Central Nervous System Neoplasms, Small Cell Lung Carcinoma

NCT05452005 2026-02-27

Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

20 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06315010 2026-02-25

REPOSE

20 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT05419076 2026-02-11

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

62 enrolled

Brain Neoplasms, Lung Neoplasms, Small Cell Lung Carcinoma

NCT05703269 2026-02-10

HYPOGRYPHE

BreastCNSDermatologicGenitourinaryThoracic

244 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Small Cell Lung Carcinoma

NCT06253871 2026-02-03

A Phase 1/1b Study of IAM1363 in HER2 Cancers

BreastCNSGastrointestinalThoracic

243 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasms, Stomach Neoplasms

NCT06810544 2026-02-02

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

191 enrolled

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmPlasma cellSarcomaThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Glioma, Lung Neoplasms

NCT05366881 2026-01-20

CAMPERR

Recruiting

7,000 enrolled

Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Leukemia, Lung Neoplasms, Lymphoma, Multiple Myeloma, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06500455 2026-01-14

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Phase 3 Recruiting

269 enrolled

BreastCNSDermatologicGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT05317858 2025-12-10

LIMITLESS

Phase 3 Recruiting

30 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT07206498 2025-11-28

WAYWIN103

48 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT06582940 2025-11-17

Elimination of PTV Margins Based on MRI-guided Adaptive Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Brain Metastasis

168 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04115254 2025-11-13

Stereotactic Magnetic Resonance Guided Radiation Therapy

CNSGastrointestinalGenitourinaryOther solid neoplasmThoracic

397 enrolled

Brain Neoplasms, Kidney Neoplasms, Lung Neoplasms, Mesothelioma, Pancreatic Neoplasms, Prostatic Neoplasms

NCT06822543 2025-09-29

TROPICAL-1

46 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05692635 2025-09-16

Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance

60 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT04890028 2025-08-17

DOPACER

BreastCNSDermatologicThoracic

52 enrolled

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms, Melanoma

NCT07118176 2025-08-12

Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers

BreastCNSEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckNETSarcomaThoracic

30 enrolled

Adrenal Gland Neoplasms, Anus Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Vaginal Neoplasms, Colorectal Neoplasms, Carcinoma, Medullary, Cholangiocarcinoma, Neuroendocrine Tumors, Solitary Fibrous Tumors

NCT06457906 2025-07-16

SHARP

Phase 3 Recruiting

340 enrolled

Brain Neoplasms, Small Cell Lung Carcinoma

NCT03175224 2025-06-27

SPARTA

CNSGastrointestinalGenitourinaryHead & NeckThoracic

497 enrolled

Brain Neoplasms, Colonic Neoplasms, Glioblastoma, Kidney Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms

NCT06673329 2025-05-14

Brodalumab in the Treatment of Immune-Related Adverse Events

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT06401824 2025-05-06

Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases

25 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT06238882 2025-05-01

Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

74 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT06728865 2024-12-11

Better Brain

70 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Meningeal Carcinomatosis

NCT06702826 2024-11-25

Cadonilimab Combined With Stereotactic Radiotherapy as Second-line Treatment for Brain Metastases

20 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT04899908 2024-10-24

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

BreastCNSDermatologicGastrointestinalThoracic

134 enrolled

Brain Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Colorectal Neoplasms

NCT06501391 2024-08-28

Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis

54 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT06476093 2024-06-26

SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer

46 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT04842812 2024-06-25

Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors

BreastCNSGastrointestinalThoracic

40 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms

NCT05977803 2024-04-09

ACROP

60 enrolled

Brain Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT05689619 2023-12-15

SILMET

CNSGastrointestinalGynecologicThoracic

70 enrolled

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT05926336 2023-09-28

The Effects of Using Different Anesthetics on the Prognosis of Primary Tumors and Its Mechanism of Action

Phase 4 Recruiting

1,316 enrolled

Brain Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms

NCT02448992 2023-05-01

Hippocampal-Sparing Prophylactic Cranial Irradiation in Pathologically Nodal Positive Non-Small-Cell Lung Cancer

Phase 2/3 Recruiting

90 enrolled

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT05033691 2021-09-05

A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases

162 enrolled