Clinical Trials

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckThoracic

11 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms

NCT03195699 2025-03-21

Oral STAT3 Inhibitor, TTI-101, in Patients with Advanced Cancers

BreastDermatologicGastrointestinalHead & NeckThoracic

64 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Melanoma, Neoplasms, Colorectal Neoplasms

NCT06687941 2025-03-21

A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

Phase 1 Active not recruiting

70 enrolled

GastrointestinalThoracic

Simpson-Golabi-Behmel syndrome, Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Liver Neoplasms, Neoplasm Metastasis, Neoplasms

NCT03552718 2024-07-17

QUILT-2.025 NANT Neoepitope Yeast Vaccine (YE-NEO-001): Adjuvant Immunotherapy Using a Personalized Neoepitope Yeast-Based Vaccine To Induce T-Cell Responses In Subjects W/ Previously Treated Cancers.

16 enrolled

BreastDermatologicGastrointestinalHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

NCT03752398 2024-07-05

DUET-3

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

198 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Histiocytoma, Malignant Fibrous, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT03685591 2024-06-26

PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

49 enrolled 33 charts

Adenocarcinoma, Breast Neoplasms, Carcinoma, Renal Cell, Camurati-Engelmann Syndrome, Liver Neoplasms, Melanoma, Mesothelioma, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Neoplasms, Squamous Cell

NCT06196294 2024-06-26

GPC3/Mesothelin-CAR-γδT Cells Against Cancers

GastrointestinalOther solid neoplasmThoracic

30 enrolled

Liver Neoplasms, Lung Neoplasms, Mesothelioma, Pancreatic Neoplasms

NCT04842812 2024-06-25

Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors

BreastCNSGastrointestinalThoracic

40 enrolled

Brain Neoplasms, Breast Neoplasms, Colonic Neoplasms, Liver Neoplasms, Lung Neoplasms

NCT05061537 2024-04-12

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckSarcomaThoracic

13 enrolled 16 charts

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Liver Neoplasms, Melanoma, Ovarian Neoplasms, Sarcoma, Colorectal Neoplasms

NCT03329950 2024-03-28

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidThoracic

132 enrolled

Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Esophageal Neoplasms, Fallopian Tube Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Mouth Neoplasms, Oropharyngeal Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Cholangiocarcinoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Hyper-IgM Immunodeficiency Syndrome

NCT05829057 2024-02-13

The IIT Study of Evaluation of P-IL-2 Single Agent and With Anti-PD-1

Phase 1 Unknown

10 enrolled

GastrointestinalGenitourinaryGynecologicThoracic

Urinary Bladder Neoplasms, Esophageal Neoplasms, Liver Neoplasms, Neoplasms, Ovarian Neoplasms, Small Cell Lung Carcinoma

NCT03849469 2023-03-30

DUET-4

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

78 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Nasopharyngeal Carcinoma, Anus Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Melanoma, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04311710 2023-02-24

CheckMate 76U

DermatologicGastrointestinalGenitourinaryThoracic

21 enrolled

Urinary Bladder Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Neoplasms, Skin Neoplasms

NCT04430842 2023-01-18

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmSarcomaThoracic

15 enrolled

Sleepiness, Mesothelioma, Malignant, Anorexia, Astrocytoma, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Headache, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Seizures, Speech Disorders, Stomach Neoplasms, Thymoma, Tongue Neoplasms, Urologic Neoplasms, Vomiting, Colorectal Neoplasms, Cholangiocarcinoma

NCT03517488 2022-12-01

DUET-2

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

150 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Anus Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Melanoma, Mesothelioma, Nasopharyngeal Neoplasms, Ovarian Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02315066 2022-04-21

Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

174 enrolled 68 charts

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT01061840 2022-03-15

Trial of Bi-shRNA-furin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced Cancer

GastrointestinalSarcomaThoracic

100 enrolled

Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Sarcoma, Ewing

NCT02947165 2022-01-31

Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.

BreastGastrointestinalGenitourinaryThoracic

120 enrolled

Breast Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT02145559 2019-04-22

A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryLymphoidThoracic

24 enrolled

Breast Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma

NCT03515252 2018-05-09

Study of Autologous Immune Killer Cells in Patients With Late Stage Hepatocellular Carcinoma or Lung Cancer

20 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Liver Neoplasms, Lung Neoplasms

NCT01012362 2017-12-28

Study of Pazopanib and Ixabepilone in Patients With Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

31 enrolled 12 charts

Breast Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Sarcoma

NCT02262455 2017-02-13

Effects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid Tumors

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

32 enrolled

Adenocarcinoma, Urinary Bladder Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Fallopian Tube Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Skin Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT01935453 2016-09-01

A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat Cancer

DermatologicGastrointestinalThoracic

18 enrolled

Liver Neoplasms, Lung Neoplasms, Melanoma, Pancreatic Neoplasms

NCT01171924 2016-03-01

A Phase Ib Expansion Study Investigating the Safety, Efficacy, and Pharmacokinetics of Intravenous CUDC-101 in Subjects With Advanced Head and Neck, Gastric, Breast, Liver and Non-small Cell Lung Cancer Tumors

BreastGastrointestinalHead & NeckThoracic

47 enrolled 8 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Liver Neoplasms, Stomach Neoplasms

NCT00581815 2015-12-28

Spectroscopy With Surface Coils and Decoupling

BreastCNSGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidSarcomaThoracic

582 enrolled

Brain Neoplasms, Breast Neoplasms, Carcinoma, Squamous Cell, Colonic Neoplasms, Hodgkin Disease, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Non-Hodgkin, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Rectal Neoplasms, Sarcoma, Sarcoma, Kaposi, Thyroid Neoplasms, Central Nervous System Neoplasms

NCT00375245 2014-01-17

Rapamycin With Grapefruit Juice for Advanced Malignancies

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther solid neoplasmThoracic

41 enrolled

Urinary Bladder Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Melanoma, Mesothelioma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms

NCT00004604 2013-02-22

Biological Therapy in Treating Patients With Metastatic Cancer

BreastGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

24 enrolled

Testicular Germ Cell Tumor, Carcinoma, Ovarian Epithelial, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Gallbladder Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Colorectal Neoplasms, Endodermal Sinus Tumor, Carcinoma, Medullary, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Inflammatory Breast Neoplasms

NCT00019513 2012-03-23

Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas

DermatologicGastrointestinalLymphoidOther hematologic neoplasmThoracic

108 enrolled

Bile Duct Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Gallbladder Neoplasms, Carcinoma, Hepatocellular, Hodgkin Disease, Liver Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mycosis Fungoides, Pancreatic Neoplasms, Sezary Syndrome, Colorectal Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Small Cell Lung Carcinoma

NCT00475956 2010-04-15

Safety and Tolerability Study of AZD2171 in Combination With AZD0530 in Patients With Advanced Solid Tumours