Clinical Trials

Phase NA Active not recruiting

Pleural Effusion, Pleural Effusion, Malignant

NCT06210685 2025-08-11

The ACES Study for Aseptic Pleural Effusion

25 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT06959719 2025-05-07

ARMSTRONG

Phase NA Recruiting

41 enrolled

MyeloidThoracic

Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Pleural Effusion, Malignant

NCT06959173 2025-05-06

Organoid-guided Personalized Treatment of Pleural Effusion

Recruiting

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT06946498 2025-04-27

FLAT

Phase NA Recruiting

Mesothelioma, Malignant, Lung Neoplasms, Mesothelioma, Pleural Effusion, Pleural Effusion, Malignant

NCT03167281 2025-02-21

ELEVATE

Phase 4 Withdrawn

Lung Neoplasms, Pleural Diseases, Pleural Effusion, Pneumothorax, Pulmonary Embolism

NCT06729931 2024-12-12

Quantitative C-Reactive Protein for Differentiating Tuberculous and Malignant Pleural Effusion: a Cross-Sectional Study

81 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT05797649 2024-11-13

Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)

Recruiting

120 enrolled

Edema, Fibrosis, Heart Failure, Infections, Neoplasms, Pleural Effusion, Tuberculosis, Hypoalbuminemia, Renal Insufficiency

NCT01766739 2024-10-26

Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma

Phase 1 Completed

18 enrolled

Lung Neoplasms, Pleural Effusion

NCT06421610 2024-05-20

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Phase 1 Recruiting

20 enrolled

Pleural Effusion, Pleural Neoplasms, Pleural Effusion, Malignant

NCT06275178 2024-02-23

Medical Thoracoscopy for Diagnosing Unexplained Pleural Effusion: a National Multicenter Retrospective Study

5,000 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT02337673 2023-09-29

Screening of Postoperative Pulmonary Complications by Electrical Impedance Tomography

130 enrolled

GastrointestinalThoracic

Airway Obstruction, Hypoxia, Pulmonary Atelectasis, Liver Diseases, Lung Diseases, Pancreatic Diseases, Pleural Effusion, Pneumonia, Pneumothorax, Pulmonary Edema, Respiratory Distress Syndrome, Stomach Neoplasms

NCT05594485 2023-07-13

Retrospective Study of Carebot AI CXR Performance in Preclinical Practice

127 enrolled

Pulmonary Atelectasis, Cardiomegaly, Lung Diseases, Lung Neoplasms, Pleural Effusion, Pneumonia, Pneumothorax, Pulmonary Edema, Rib Fractures

NCT05935696 2023-07-07

TUS-TBE

Pleural Effusion, Tuberculosis, Pleural, Pleural Effusion, Malignant

NCT05910112 2023-06-18

PROSPECT

2,000 enrolled

Mesothelioma, Malignant, Pleural Diseases, Pleural Effusion, Pleural Neoplasms, Pneumothorax, Pleural Effusion, Malignant

NCT03449602 2023-03-29

MICRO

Lung Neoplasms, Neoplasm Metastasis, Pleural Effusion, Tuberculosis, Pleural Effusion, Malignant

NCT05539183 2022-09-14

Collection of Pleural Effusion Fluid

50 enrolled

Neoplasm Metastasis, Pleural Effusion

NCT04235998 2022-05-11

Value of Additional Upfront Systematic Lung Ultrasound in the Workup of Patients With Unilateral Pleural Effusion

57 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT05121233 2021-11-16

Local Anesthesia Versus Combined Local Anesthesia With Single Dose Analgesia on Pain Control During Thoracic Ultrasound Guided Procedures

Phase 4 Unknown

Lung Neoplasms, Pleural Effusion, Pleural Neoplasms, Pneumothorax, Empyema, Pleural, Respiratory Aspiration

NCT01374542 2021-10-01

Respiratory Endoscopy: Diagnostic Yield, Technical Factors and Complications

4,000 enrolled

Lung Neoplasms, Pleural Effusion, Respiratory Tract Infections, Lung Diseases, Interstitial

NCT04887545 2021-05-14

Immune- and Microenvironment- Proteogenomics Profiling for Classifying Lung Cancer Patients

200 enrolled

Lung Neoplasms, Neoplasms, Pleural Effusion

NCT04793607 2021-03-11

IMPE-F

50 enrolled

Neoplasms, Pleural Effusion, Pleural Effusion, Malignant

NCT01999985 2020-11-27

Phase I Trial of Afatinib (BIBW 2992) and Dasatinib in Non-small Cell Lung Cancer (NSCLC)

Phase 1 Completed

25 enrolled 10 charts

Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Pleural Diseases, Pleural Effusion, Pleural Neoplasms, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms, Pleural Effusion, Malignant

NCT03661801 2020-11-05

INVEST

313 enrolled

Lung Neoplasms, Pleural Effusion, Respiration Disorders

NCT04233359 2020-09-28

A Randomised Study Evaluating Diagnostics of Pleural Effusion Among Patients Suspect of Cancer.

Phase NA Terminated

4 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT03597828 2020-06-30

Respiratory Function of Dexmedetomidine in Patients Undergoing Pleuroscopy

60 enrolled

Bronchiolitis Obliterans Syndrome, Pleural Diseases, Pleural Effusion, Pleural Effusion, Malignant

NCT00299962 2020-03-18

Gene Therapy for Pleural Malignancies

Phase 1 Completed

17 enrolled

Mesothelioma, Malignant, Pleural Effusion

NCT03678090 2020-03-05

The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.

Phase 2 Withdrawn

Lung Neoplasms, Pleural Effusion

NCT04254445 2020-02-18

Use of Guidance Videos to Increase Engagement and Decrease Anxiety in Patients Undergoing Pleural Tap

Pleural Effusion, Pleural Effusion, Malignant

NCT04263688 2020-02-12

Multicenter Observational Study of Advanced Non-small Cell Lung Cancer With Malignant Pleural Effusion

300 enrolled

Carcinoma, Non-Small-Cell Lung, Pleural Effusion

NCT02891642 2020-02-06

Liquid Biopsy With Immunomagnetic Beads Capture Technique for Malignant Cell Detection in Body Fluid

1,000 enrolled

Ascites, Neoplasms, Pleural Diseases, Pleural Effusion, Pleural Neoplasms

NCT03319472 2019-12-10

MAPED

439 enrolled

Fasting, Neoplasms, Pleural Effusion

NCT03210298 2019-10-08

PIPACRegis

GastrointestinalGynecologicOther solid neoplasmThoracic

1,000 enrolled

Mesothelioma, Malignant, Appendiceal Neoplasms, Ascites, Gallbladder Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Peritoneal Neoplasms, Pleural Effusion, Pseudomyxoma Peritonei, Stomach Neoplasms, Colorectal Neoplasms

NCT01722149 2019-08-07

Re-directed T Cells for the Treatment (FAP)-Positive Malignant Pleural Mesothelioma

Phase EARLY_PHASE1 Completed

4 enrolled

Mesothelioma, Malignant, Pleural Effusion

NCT03973957 2019-06-04

TOPIC

124 enrolled

Pleural Diseases, Pleural Effusion, Pleural Effusion, Malignant

NCT01612975 2018-02-15

The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection

Phase 2 Terminated

7 enrolled

Lung Neoplasms, Pleural Effusion, Pleural Effusion, Malignant

NCT01952327 2017-06-14

ADEPT

Phase NA Terminated

2 enrolled

Pleural Effusion

NCT00753714 2016-10-17

ZELIG

Phase 2 Completed

124 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT00896285 2015-07-20

TIME-1

Phase NA Completed

4 enrolled

Neoplasms, Pleural Effusion, Pleural Effusion, Malignant

NCT01580618 2015-01-06

Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy

Phase 2/3 Terminated

20 enrolled 11 charts

Neoplasms, Pleural Effusion

NCT00799240 2014-11-07

IMPACT

Phase 2 Completed

27 enrolled

Insulin-Like Growth Factor I, Resistance To, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pleural Effusion

NCT01776372 2014-05-13

Comparison of Pleural Drainage Systems on Reducing Pleural Effusion Formation Following Lung Resection

Phase NA Completed

103 enrolled

Lung Neoplasms, Pleural Effusion

NCT01854866 2013-10-01

Safety and Effectiveness Study of Tumor Cell-derived Microparticles to Treat Malignant Ascites and Pleural Effusion

Phase 2 Unknown

30 enrolled

Ascites, Pleural Effusion, Pleural Effusion, Malignant

NCT01819363 2013-03-27

Relationship Between Pleural Elastance and Effectiveness of Pleurodesis on Recurrent Malignant Pleural Effusion

140 enrolled

Pleural Effusion, Pleural Effusion, Malignant

NCT01141946 2012-07-17

CT0018

46 enrolled