Clinical Trials

Lung Neoplasms, Recurrence

NCT06007937 2026-02-05

A Study of Lorlatinib in Combination With Ramucirumab in People With Lung Cancer

Phase 1/2 Recruiting

56 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Recurrence

NCT04467723 2026-01-28

Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC

Phase 1/2 Recruiting

25 enrolled

BreastGastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT05150691 2026-01-28

A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors

Phase 1/2 Recruiting

796 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Neoplasms, Recurrence, Stomach Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT07277413 2026-01-20

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

GastrointestinalGenitourinaryOther solid neoplasmThoracic

260 enrolled

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Mesothelioma, Malignant, Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Mesothelioma, Neoplasm Metastasis, Recurrence

NCT07347977 2026-01-16

LidCRM

Phase NA Not yet recruiting

1,400 enrolled

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT04777994 2025-12-23

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

GenitourinaryHead & NeckThoracic

248 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Neoplasms, Recurrence

NCT06922539 2025-12-15

ST-001 nanoFenretinide in Relapsed/ Refractory Small Cell Lung Cancer

44 enrolled

Phase 2 Active not recruiting

Recurrence, Small Cell Lung Carcinoma

NCT03999710 2025-11-28

Determining Whether Durvalumab in Combination With Radiation Therapy Can Prevent the Progression of Non-Small Cell Lung Cancer

61 enrolled

Phase 1/2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Recurrence

NCT07206563 2025-10-03

Penfluridol for Relapsed/Refractory Small Cell Cancers

33 enrolled

Recurrence, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT05253807 2025-08-05

FIGHT-210

Phase 2 Completed

8 enrolled 13 charts

Phase 2 Not yet recruiting

Acrocephalosyndactylia, Carcinoma, Non-Small-Cell Lung, Recurrence

NCT07097948 2025-08-01

Adjuvant

40 enrolled

BreastGynecologicThoracic

Recurrence, Small Cell Lung Carcinoma

NCT05274451 2025-07-01

A Study to Investigate LYL797 in Adults With Solid Tumors

Phase 1 Terminated

57 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Fallopian Tube Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Recurrence, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05891197 2025-07-01

START

Terminated

10 enrolled

BreastGynecologicThoracic

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Fallopian Tube Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Recurrence, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04358237 2025-06-04

LUPER

Phase 1/2 Completed

28 enrolled

Recurrence, Small Cell Lung Carcinoma

NCT02029729 2025-05-29

DISCOVER

11 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Recurrence

NCT05701787 2025-05-22

Molecular Landscape Analysis and Clinical Implications for NSCLC Patients With Rare Mutations

Recruiting

500 enrolled

Other solid neoplasmThoracic

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT05455424 2025-05-15

NERO

Phase 2 Completed

88 enrolled

Mesothelioma, Malignant, Mesothelioma, Recurrence

NCT05736731 2025-04-25

EVEREST-1

Phase 1/2 Active not recruiting

160 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms, Pancreatic Neoplasms, Recurrence, Colorectal Neoplasms

NCT05275673 2025-04-24

A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer

Phase 2 Terminated

7 enrolled 11 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicMyeloidOther hematologic neoplasmSarcomaThoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Recurrence

NCT03154190 2025-01-24

Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

Phase NA Completed

128 enrolled 24 charts

Urinary Bladder Neoplasms, Bone Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Melanoma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Stomach Neoplasms, Leukemia, Myeloid, Acute, Disease Progression, Triple Negative Breast Neoplasms

NCT05324436 2025-01-20

A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)

Completed

75 enrolled

Other solid neoplasmThoracic

Mesothelioma, Malignant, Recurrence

NCT04855929 2024-11-08

ANV419-001

55 enrolled

Phase NA Active not recruiting

Disease, Lung Neoplasms, Neoplasms, Recurrence

NCT04795713 2024-11-04

Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1

Phase 1 Terminated

64 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Recurrence

NCT03075072 2024-10-23

Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial

196 enrolled

BreastCNSDermatologicGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Renal Cell, Kidney Neoplasms, Lung Neoplasms, Melanoma, Recurrence

NCT06648200 2024-10-18

Toripalimab and JS004 Combined With Platinum-based Chemotherapy for Relapsed and Extensive-stage Small Cell Lung Cancer

Phase 2 Not yet recruiting

100 enrolled

Recurrence, Small Cell Lung Carcinoma

NCT02595866 2024-08-09

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer

DermatologicGastrointestinalLymphoidSarcomaThoracic

58 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Lung Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Neoplasm Metastasis, Neoplasms, Recurrence, Sarcoma, Kaposi, HIV Infections

NCT02889666 2024-04-17

CCODG-NSCLC

500 enrolled

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT00020267 2024-03-04

Vaccine Therapy in Treating Patients With Metastatic Cancer

BreastDermatologicGastrointestinalSarcomaThoracic

Uveal Melanoma, Bone Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Eye Neoplasms, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Skin Neoplasms, Colorectal Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Breast Neoplasms, Male, Muscle Neoplasms, Genetic Diseases, Inborn, Histiocytoma, Malignant Fibrous

NCT03257722 2024-02-28

PIL

Phase 1/2 Terminated

4 enrolled 5 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Recurrence

NCT06262386 2024-02-16

Combined Relapse Prediction Model for Resectable Non-Small Cell Patients - a Prospective Clinical Feasibility Trial

Phase NA Recruiting

358 enrolled

GastrointestinalGenitourinaryThoracic

Lung Neoplasms, Neoplastic Cells, Circulating, Recurrence

NCT05861947 2024-01-31

JIVAN

Phase 1 Unknown

30 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Colonic Neoplasms, Esophageal Neoplasms, Kidney Neoplasms, Recurrence, Stomach Neoplasms

NCT05189054 2023-12-27

Safety and Efficacy of SBRT in the Reirradiation for Ultra-central Thoracic Malignant Tumors

Recruiting

40 enrolled

Recurrence, Thoracic Neoplasms

NCT04636775 2023-12-11

Microbiome in Immunotherapy naïve NSCLC Patients Receiving PD-1/L1 Blockade (MIP_NSCLC)

Unknown

46 enrolled

BreastGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT03330405 2023-10-13

Javelin Parp Medley: Avelumab Plus Talazoparib In Locally Advanced Or Metastatic Solid Tumors

Phase 1/2 Terminated

223 enrolled 50 charts

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Recurrence

NCT03215810 2023-07-24

Nivolumab and Tumor Infiltrating Lymphocytes (TIL) in Advanced Non-Small Cell Lung Cancer

20 enrolled 10 charts

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Recurrence, Carcinoma, Adenosquamous

NCT03805841 2023-06-28

RAIN

Phase 2 Terminated

41 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT03758781 2023-04-14

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

GenitourinaryHead & NeckThoracic

12 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Neoplasm Metastasis, Recurrence

NCT03713944 2023-03-01

Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung Cancer

Phase 2 Terminated

30 enrolled 28 charts

BreastGastrointestinalGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT00248404 2022-05-16

NB1011 Administered by Continuous Infusion in Cancers That Overexpress Thymidylate Synthase (TS)

Phase 1/2 Completed

155 enrolled

Breast Neoplasms, Lung Neoplasms, Neoplasms, Ovarian Neoplasms, Recurrence, Colorectal Neoplasms

NCT02460367 2022-04-06

Immunotherapy Combination Study in Advanced Previously Treated Non-Small Cell Lung Cancer

Phase 1 Terminated

16 enrolled

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT02963610 2021-12-30

Phase I/II Study of Lenalidomide Plus Pembrolizumab in Patients With Solid Tumors With Expansion in Non-small Cell Lung Cancer

Phase 1/2 Terminated

3 enrolled 5 charts

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT02674568 2021-07-30

TRINITY

Phase 2 Completed

342 enrolled 18 charts

Recurrence, Small Cell Lung Carcinoma

NCT04634630 2021-06-01

The Influence of Cancer Stem-cells on Risk of Relapse in Patients Harboring Adenocarcinoma and Squamous Cell Carcinoma of the Lung

Completed

35 enrolled