Clinical Trials

Carcinoma, Non-Small-Cell Lung

NCT04101357 2025-03-18

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411

54 enrolled 30 charts

Small Cell Lung Carcinoma

NCT04923776 2024-12-30

Liver Directed RT + Chemo-immunotherapy for ES-SCLC

2 enrolled 1 chart

Small Cell Lung Carcinoma

NCT03191786 2024-10-23

IPSOS

453 enrolled 20 charts

Carcinoma, Non-Small-Cell Lung

NCT03526900 2024-10-09

ATEZO-BRAIN

40 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT02927301 2024-09-19

A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)

181 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT04426825 2024-05-21

A Study of Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer

23 enrolled 23 charts

Carcinoma, Non-Small-Cell Lung

NCT04610684 2024-03-13

Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases

3 enrolled 13 charts

CNSThoracic

Brain Neoplasms, Small Cell Lung Carcinoma

NCT04099836 2023-12-26

Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib

7 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung

NCT03014648 2023-12-13

Evaluating the Efficacy of Atezolizumab in Advanced Non-small Cell Lung Cancer (NSCLC)

28 enrolled 22 charts

Advanced Non-small Cell Lung Cancer

NCT02716038 2023-12-12

Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC

39 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT02657434 2023-11-21

A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower 132)

578 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT04639245 2023-08-03

Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer

BreastGenitourinaryThoracic

1 enrolled 6 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Lung Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT02763579 2023-07-28

IMpower133

503 enrolled 23 charts 1 FDA

Small Cell Lung Carcinoma

NCT02919449 2023-07-21

Dose Escalation Trial of Intra-Tumoral Injection of NIS Measles Virus in Combination With Atezolizumab

Phase 1 Terminated

2 enrolled 4 charts

Carcinoma, Non-Small-Cell Lung

NCT03102242 2023-05-24

Atezolizumab Immunotherapy in Patients With Advanced NSCLC

64 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung

NCT02409342 2023-03-15

A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]

572 enrolled 32 charts 2 FDA

Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung Cancer

NCT03138889 2023-03-10

PROPEL

162 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung

NCT03713944 2023-03-01

Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung Cancer

30 enrolled 28 charts

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT03455556 2023-01-06

Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer

Phase 1 Terminated

1 enrolled 1 chart

Carcinoma, Non-Small-Cell Lung

NCT02367794 2022-03-21

A Study of Atezolizumab in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-Paclitaxel Compared With Carboplatin + Nab-Paclitaxel in Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower131]

1,021 enrolled 33 charts

Squamous Non-Small Cell Lung Cancer

NCT04422210 2021-11-08

A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).

Phase 1 Terminated

2 enrolled

Small Cell Lung Carcinoma

NCT02031458 2020-01-06

BIRCH

667 enrolled 29 charts

Carcinoma, Non-Small-Cell Lung

NCT02008227 2019-12-20

OAK

1,225 enrolled 32 charts

Non-Squamous Non-Small Cell Lung Cancer

NCT03023423 2019-11-20

DARZALEX

Phase 1/2 Completed

100 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT01903993 2019-10-02

A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum Therapy - "POPLAR"

287 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung

NCT02630186 2019-07-05

A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC

3 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT02409355 2019-02-15

A Study of Atezolizumab Compared With Gemcitabine Plus (+) Cisplatin or Carboplatin for PD-L1-Selected Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower111)

Phase 3 Terminated

8 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung

NCT01846416 2019-01-08

A Study of Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [FIR]

138 enrolled 21 charts