Clinical Trials

387 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Colorectal Neoplasms

NCT06607185 2026-03-13

A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

GastrointestinalGynecologicThoracic

750 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Esophageal Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT06704724 2026-03-13

A Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.

30 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT06447662 2026-02-25

A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

330 enrolled

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Lung Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Carcinoma, Pancreatic Ductal

NCT05403723 2026-02-19

Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLC

Phase 1 Suspended

50 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT03819465 2026-02-11

MAGELLAN

175 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04809103 2026-02-06

Intratumoral Cisplatin for Resectable NSCLC

6 enrolled 6 charts

Carcinoma, Non-Small-Cell Lung

NCT04648033 2026-01-29

ARCADIAN

21 enrolled 21 charts

Locally Advanced Non-Small Cell Lung Cancer

NCT06077500 2026-01-06

DAREONᵀᴹ-8

45 enrolled

Small Cell Lung Carcinoma

NCT03760575 2025-12-04

Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

20 enrolled

Mesothelioma, Malignant

NCT04686305 2025-11-13

DL03

244 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02495896 2025-11-10

Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors

GastrointestinalHead & NeckThoracic

61 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Gallbladder Neoplasms, Pancreatic Neoplasms

NCT03228537 2025-11-10

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

28 enrolled 17 charts

Mesothelioma, Malignant

NCT04311762 2025-10-31

Phase 1 Trial of Endobronchial Ultrasound-Guided Transbronchial Needle Injection of Cisplatin for Stage IV Lung Cancer

16 enrolled

Lung Cancer Metastatic

NCT02817633 2025-10-28

A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)

DermatologicGastrointestinalThoracic

463 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Colorectal Neoplasms

NCT05599984 2025-10-20

Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors

288 enrolled

CNSEndocrineThoracic

Neoplasms, Central Nervous System Neoplasms, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT04162015 2025-09-12

A Study of Nivolumab and Chemotherapy Followed by Surgery for Mesothelioma

22 enrolled

Mesothelioma, Malignant

NCT04153565 2025-07-17

MK-3475-A17

19 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Mesothelioma

NCT06969612 2025-06-06

A Study on the Efficacy and Safety of Golidocitinib Combined With Tislelizumab and Chemotherapy as First-line Treatment for Advanced NSCLC

21 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06839105 2025-05-31

A Clinical Study to Evaluate the Safety and Tolerability of AWT020 in Patients With Advanced Malignancies

DermatologicGastrointestinalGenitourinaryThoracic

214 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Colorectal Neoplasms

NCT04526691 2025-05-20

Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)

145 enrolled

Phase 1 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT06963502 2025-05-09

A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Patients With Advanced Solid Tumors

762 enrolled

Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms

NCT05504278 2025-01-27

Efficacy and Safety of IBI351 in Combination With Chemotherapy in Advanced Non-squamous Non-small Cell Lung Cancer Subjects With KRAS G12C Mutation

144 enrolled

Advanced Non-Small Cell Lung Cancer

NCT03509012 2025-01-14

CLOVER

Phase 1 Not yet recruiting

105 enrolled

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT06732258 2024-12-27

Low-dose Radiotherapy Combined with Concurrent Chemotherapy, Toripalimab and Tifcemalimab in the Treatment of ES-SCLC

12 enrolled

Small Cell Lung Carcinoma

NCT02009449 2024-11-15

IVY

BreastDermatologicGastrointestinalGenitourinaryGynecologicThoracic

353 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms

NCT04287894 2024-11-06

Induction

Phase 1 Terminated

18 enrolled

Carcinoma, Non-Small-Cell Lung

NCT01899989 2024-10-04

Stereotactic Body Radiation Therapy for Inoperable Locally-advanced Non-small Cell Lung Cancer

39 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04999761 2024-09-25

AB122 Platform Study

GastrointestinalHead & NeckSarcomaThoracic

917 enrolled

Biliary Tract Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Neoplasm Metastasis, Stomach Neoplasms, Colorectal Neoplasms, Sarcoma, Alveolar Soft Part

NCT06594874 2024-09-19

A Phase Ib Study of HS-10370 in Addition to Other Anti-cancer Therapies in Participants with KRAS G12C Mutation Advanced Solid Tumors

Phase 1 Not yet recruiting

350 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT02815592 2024-09-04

Trial of BMS-986012 in Combination With Platinum and Etoposide

12 enrolled

Small Cell Lung Carcinoma

NCT03850067 2024-08-26

A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung Cancer

90 enrolled

Small Cell Lung Carcinoma

NCT02707666 2024-07-31

A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesothelioma

Phase 1 Terminated

7 enrolled

Mesothelioma, Malignant

NCT00254384 2024-07-05

Docetaxel, Cisplatin, and Erlotinib Hydrochloride in Treating Patients With Stage I-III Non-small Cell Lung Cancer Following Surgery

50 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02225405 2024-05-08

Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung Cancer

26 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02889666 2024-04-17

CCODG-NSCLC

500 enrolled

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT02897375 2023-10-10

Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumors