Clinical Trials

Phase NA Active not recruiting

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT02194738 2026-03-18

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

8,300 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02535312 2026-03-18

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

30 enrolled 15 charts

Phase 2 Active not recruiting

Mesothelioma, Malignant

NCT03737994 2026-03-18

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

10 enrolled 17 charts

Phase 3 Active not recruiting

Lung Neoplasms

NCT03811002 2026-03-18

Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)

544 enrolled 29 charts

Phase 3 Active not recruiting

Lung Neoplasms

NCT04092283 2026-03-18

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

660 enrolled

Phase 1/2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06694454 2026-03-18

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

60 enrolled

Pathologic Complete Response, Carcinoma, Non-Small-Cell Lung

NCT04267848 2026-03-17

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Phase 3 Recruiting

1,210 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05198830 2026-03-17

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Phase 2 Recruiting

42 enrolled

Phase 1 Active not recruiting

Adenocarcinoma of Lung, Lung Neoplasms

NCT03228537 2025-11-10

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

28 enrolled 17 charts

Phase 2 Active not recruiting

Mesothelioma, Malignant

NCT00334815 2025-08-24

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

29 enrolled 10 charts

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar

NCT03382561 2025-07-03

Cisplatin/Carboplatin and Etoposide With or Without Nivolumab in Treating Patients With Extensive Stage Small Cell Lung Cancer

160 enrolled 12 charts

Small Cell Lung Carcinoma

NCT00324805 2025-03-03

Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery

1,501 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT01642251 2023-05-06

Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer

Phase 1/2 Completed

156 enrolled 13 charts

EndocrineThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Neuroendocrine, Carcinoma, Small Cell, Small Cell Lung Carcinoma

NCT00453154 2023-04-04

Cisplatin or Carboplatin, and Etoposide With or Without Sunitinib Malate in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Phase 1/2 Completed

156 enrolled 14 charts

Small Cell Lung Carcinoma

NCT02535325 2022-06-30

Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer

Phase 1 Completed

17 enrolled

Adenocarcinoma of Lung

NCT00887159 2021-01-05

A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients With Extensive Stage

168 enrolled 11 charts

Small Cell Lung Carcinoma

NCT01822496 2019-08-05

Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer

Phase 2 Terminated

59 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung

NCT00924209 2018-11-30

A Phase II Study of Neo-Adjuvant Gemcitabine, Cisplatin and Bevacizumab in Stage IIIA (N2) Non-Squamous Cell Non-Small Cell Lung Cancer

Phase 2 Terminated

7 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung

NCT00926640 2018-10-19

A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers

Phase 1 Completed

28 enrolled

EndocrineThoracic

Carcinoma, Carcinoma, Neuroendocrine, Small Cell Lung Carcinoma

NCT01445392 2018-08-03

SS1(dsFV)PE38 Plus Pemetrexed and Cisplatin to Treat Malignant Pleural Mesothelioma

Phase 1 Terminated

24 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT00963807 2017-03-17

A Comparison of FLT to FDG PET/CT in the Early Assessment of Chemotherapy Response in Stage IB-IIIA Resectable NSCLC

26 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung

NCT00004547 2015-11-18

Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapy

GastrointestinalGynecologicOther solid neoplasmThoracic

188 enrolled 11 charts

Abdominal Neoplasms, Colonic Neoplasms, Mesothelioma, Peritoneal Neoplasms

NCT00387699 2015-04-28

Bevacizumab, Cisplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

79 enrolled

Lung Neoplasms

NCT00118235 2014-06-17

Cisplatin, Irinotecan, and Bevacizumab, in Treating Patients With Small Cell Lung Cancer

72 enrolled

Extensive Stage Small Cell Lung Cancer

NCT00066742 2014-05-15

Tirapazamine Combined With Chemo and RT in Limited-Stage Small Cell Lung Cancer

72 enrolled 8 charts

Limited Stage Small Cell Lung Cancer

NCT00079040 2014-05-14

Cisplatin, Etoposide, and Bevacizumab in Treating Patients With Previously Untreated Extensive Stage Small Cell Lung Cancer

65 enrolled 7 charts

Extensive Stage Small Cell Lung Cancer

NCT00544596 2014-04-02

R-(-)-Gossypol Acetic Acid, Cisplatin, and Etoposide in Treating Patients With Advanced Solid Tumors or Extensive Stage Small Cell Lung Cancer

Phase 1 Completed

27 enrolled

Extensive Stage Small Cell Lung Cancer

NCT00027703 2014-02-11

Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Malignant Mesothelioma

106 enrolled

Mesothelioma, Malignant, Solitary Fibrous Tumor, Pleural

NCT00514293 2014-01-10

Bexarotene, Tretinoin, and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

39 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00024271 2014-01-06

Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer

Mesothelioma, Malignant

NCT00002822 2013-12-19

Combination Chemotherapy Followed by Radiation Therapy in Patients With Small Cell Lung Cancer

400 enrolled

Lung Neoplasms

NCT00003364 2013-12-19

Radiation Therapy Plus Combination Chemotherapy In Treating Patients With Limited Stage Small Cell Lung Cancer

398 enrolled

Lung Neoplasms

NCT00006048 2013-12-19

ZD 1839 Plus Combination Chemotherapy in Treating Patients With Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00253591 2013-12-19

Radiation Therapy With or Without Vinorelbine and Cisplatin in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

Phase 2/3 Completed

500 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00003240 2013-12-18

Standard Therapy Given With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer

1,800 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00004100 2013-12-18

Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00005825 2013-12-18

Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00039039 2013-12-18

Combination Chemotherapy Followed by Radiation Therapy With or Without Paclitaxel in Treating Patients With Unresectable Stage III Non-Small Cell Lung Cancer

300 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00003159 2013-12-04

Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer

600 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00003583 2013-12-04

Amifostine to Prevent Side Effects in Patients Who Are Receiving Chemotherapy and Radiation Therapy for Limited-Stage Small Cell Lung Cancer

20 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00004264 2013-12-04

Docetaxel, Cisplatin, and Amifostine in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase 1/2 Unknown

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00003053 2013-09-20

Combination Chemotherapy in Treating Patients With Stage I, II, or IIIA Non-small Cell Lung Cancer That Has Been Surgically Removed

750 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00004887 2013-09-20

Paclitaxel and Carboplatin Chemotherapy Compared With Standard Chemotherapy in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer That Cannot Be Removed During Surgery

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00055965 2013-09-20

Hospitalization Rates of Patients With Non-Small Cell Lung Cancer Treated With Gemcitabine and Either Cisplatin or Carboplatin

400 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00002887 2013-09-17

Hydroxyurea Plus Combination Chemotherapy in Patients With Non-small Cell Lung Cancer

Phase 1 Unknown

30 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00006212 2013-09-17

Phosphorus-32 Plus Radiation Therapy and Chemotherapy in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer

Phase 1 Unknown

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00112710 2013-08-26

Gemcitabine in Combination With Either Cisplatin or Carboplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

1,350 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00398385 2013-08-12

Gemcitabine and Cisplatin Before or After Surgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer

170 enrolled