Clinical Trials

Non-Small Cell Lung Cancer Metastatic

NCT06632327 2026-03-04

Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

Phase 3 Recruiting

1,100 enrolled

Lung Neoplasms

NCT06616623 2026-02-27

Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

Phase 1 Recruiting

24 enrolled

Phase 1 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04919369 2026-02-13

All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer

18 enrolled

Phase 1/2 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03830918 2026-02-12

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

59 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT06731270 2026-02-12

Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy

Phase 2 Recruiting

20 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03896074 2026-02-09

BEAT

206 enrolled

Non-small-cell Lung Cancer Patients

NCT04081688 2026-02-05

Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLC

Phase 1 Terminated

16 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT07339059 2026-01-30

SG and Immunotherapy as Maintenance Therapy for Extensive-stage Small-cell Lung Cancer

Phase 2 Recruiting

35 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT05340309 2026-01-29

Subcutaneous Atezolizumab for the Treatment of Non-small Cell Lung Cancer

5 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04467723 2026-01-28

Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC

Phase 1/2 Recruiting

25 enrolled

Carcinoma, Non-Small-Cell Lung, Recurrence

NCT05746481 2026-01-22

Tiragolumab and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain Metastases

3 enrolled 12 charts

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT04691817 2026-01-07

Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

Phase 1/2 Recruiting

28 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04367311 2026-01-02

Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)

100 enrolled

Lung Neoplasms

NCT05470595 2025-12-30

LCNEC-ALPINE

67 enrolled

EndocrineThoracic

Lung Neoplasms, Carcinoma, Neuroendocrine

NCT06908993 2025-12-17

COMET

Phase 3 Recruiting

133 enrolled

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT03977194 2025-11-18

ELDERLY

510 enrolled

Non Small Cell Lung Cancer Metastatic

NCT04549428 2025-11-18

Atezolizumab Plus 8 Gy Single-fraction Radiotherapy for Advanced Oligoprogressive NSCLC

12 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05781308 2025-11-18

ADAPTABLE

156 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04373369 2025-11-03

Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

11 enrolled 10 charts

Small Cell Lung Carcinoma

NCT06807632 2025-10-20

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

Phase 1 Recruiting

24 enrolled

Phase 1 Active not recruiting

Small Cell Lung Carcinoma

NCT05334329 2025-10-15

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

6 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03693014 2025-10-06

A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

69 enrolled

GenitourinaryThoracic

Urinary Bladder Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT04273061 2025-09-22

CAPTIV-8

Phase 2 Recruiting

200 enrolled

Breast Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Sarcoma, Skin Neoplasms, Urogenital Neoplasms

NCT04221529 2025-09-08

SPACE

Phase 2 Completed

70 enrolled

SCLC, Extensive Stage

NCT03977467 2025-08-27

Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 Inhibitor

Phase 2 Completed

46 enrolled 12 charts

Phase 2 Not yet recruiting

Carcinoma, Non-Small-Cell Lung

NCT06713798 2025-06-24

INDIGO

115 enrolled

Lung Neoplasms

NCT04911166 2025-06-17

Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy

Phase 1 Terminated

13 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04042558 2025-05-31

GFPC 06-2018

Phase 2 Completed

150 enrolled

Carcinoma, Non-Small-Cell Lung

NCT02314481 2025-05-23

DARWINII

50 enrolled

Carcinoma, Non-Small-Cell Lung, Genomic Instability

NCT05825625 2025-05-23

NeoTRACK - Dissection of IO Efficacy in NSCLC by Longitudinal tracKing

35 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04512430 2025-04-02

Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated Patients

4 enrolled 9 charts