Clinical Trials

351 enrolled

Carcinoma, Non-Small-Cell Lung

NCT05613413 2026-01-08

LUNG-IST-127

36 enrolled

Metastatic Squamous Non-Small Cell Lung Carcinoma

NCT05141357 2025-12-24

HBI-8000

5 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT03634241 2025-12-22

Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study

45 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05570825 2025-12-04

SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer

30 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04165083 2025-11-26

MK-3475-01B

102 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT05256381 2025-11-17

A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors

GastrointestinalGynecologicThoracic

166 enrolled 43 charts

Carcinoma, Non-Small-Cell Lung, Carcinoma, Hepatocellular, Ovarian Neoplasms, Colorectal Neoplasms

NCT07223424 2025-11-10

PSI-Immune

DermatologicGastrointestinalGenitourinaryGynecologicThoracic

480 enrolled

Adenocarcinoma Of Esophagus, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Uterine Cervical Neoplasms, Colitis, Ulcerative, Colonic Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma

NCT02316002 2025-11-06

Phase II Study of Pembrolizumab After Curative Intent Treatment for Oligometastatic Non-Small Cell Lung Cancer

51 enrolled 7 charts

Oligometastatic Non-small Cell Lung Cancer (NSCLC)

NCT05117242 2025-11-06

Safety and Efficacy Study of GEN1046 as a Single Agent or in Combination With Pembrolizumab for Treatment of Recurrent (Non-small Cell) Lung Cancer

125 enrolled

Non Small Cell Lung Cancer Metastatic

NCT04225117 2025-11-03

A Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)

BreastGastrointestinalHead & NeckThoracic

329 enrolled

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Head and Neck Neoplasms, Triple Negative Breast Neoplasms

NCT04964960 2025-10-31

Pembro+Chemo in Brain Mets

3 enrolled 7 charts

CNSThoracic

Brain Neoplasms, Lung Neoplasms, Neoplasms

NCT04524689 2025-10-29

CARMEN-LC05

57 enrolled 26 charts

Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)

NCT06558799 2025-10-28

LUNAR-4

69 enrolled

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03049618 2025-10-22

Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475

42 enrolled 40 charts

Head & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung

NCT05846646 2025-10-20

Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC

6 enrolled 7 charts

GenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell

NCT03693014 2025-10-06

A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

69 enrolled

GenitourinaryThoracic

Urinary Bladder Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT07207395 2025-10-06

A Study of Orally Administered JBI-802 Alone or in Combination With Pembrolizumab for Patients With Non-small Cell Lung Cancer With an STK11 Mutation.

30 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04914897 2025-10-02

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)

Other solid neoplasmThoracic

106 enrolled 21 charts

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung

NCT07122687 2025-09-30

IBI363 Combined With Chemotherapy or Pembrolizumab Combined With Chemotherapy as Neoadjuvant Therapy in Resectable Stage IB-III Non-Squamous Non-Small Cell Lung Cancer

170 enrolled

Resectable Stage IB-III Non-Squamous Non-Small Cell Lung Cancer

NCT06822543 2025-09-29

TROPICAL-1

46 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03184571 2025-09-25

Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

99 enrolled 20 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung

NCT02628067 2025-09-22

KEYNOTE 158

EndocrineGastrointestinalGynecologicHead & NeckNETOther solid neoplasmThoracic

1,609 enrolled 5 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Anus Neoplasms, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoid Tumor, Uterine Cervical Neoplasms, Mesothelioma, Parotid Neoplasms, Salivary Gland Neoplasms, Thyroid Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma, Neuroendocrine Tumors, Microsatellite Instability, Small Cell Lung Carcinoma

NCT05318573 2025-09-04

A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer

120 enrolled

GenitourinaryThoracic

Advanced Urothelial Carcinoma

NCT06364917 2025-09-03

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

24 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03463460 2025-08-24

Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic Cancer

30 enrolled

Thymoma

NCT03322540 2025-08-22

Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)

154 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT05609578 2025-08-17

Combination Therapies With Adagrasib in Patients With Advanced NSCLC With KRAS G12C Mutation

90 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02546986 2025-08-08

Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer

100 enrolled 27 charts