NCT01526928 2020-08-04Study to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) PatientsClovis Oncology, Inc.Phase 1/2 Terminated612 enrolled 34 charts
NCT02322281 2019-08-14TIGER-3: Open Label, Multicenter Study of Rociletinib (CO-1686) Mono Therapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR NSCLC Who Have Failed at Least One Previous EGFR-Directed TKI and Platinum-doublet ChemotherapyClovis Oncology, Inc.Phase 3 Terminated149 enrolled 17 charts
NCT02630186 2019-07-05A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLCClovis Oncology, Inc.Phase 1/2 Terminated3 enrolled 8 charts
NCT02580708 2018-10-02Phase 1/2 Study of the Safety and Efficacy of Rociletinib in Combination With Trametinib in Patients With mEGFR-positive Advanced or Metastatic Non-small Cell Lung CancerClovis Oncology, Inc.Phase 1/2 Terminated7 enrolled
NCT02705339 2016-05-17Rociletinib Genomic Landscape in Non-small Cell Lung Cancer (NSCLC)Washington University School of MedicinePhase 2 Withdrawn