Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China
Completed
9,759 enrolled
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
Completed
64 enrolled
Gemcitabine, Carboplatin, and Lenalidomide for Treatment of Advanced/Metastatic Urothelial Cancer and Other Solid Tumors
Phase 1 Completed
18 enrolled
Mobile Sensor Technologies to Assess General Symptomology of People With Cancer
Completed
49 enrolled
Testing the Safety of Adding Either Monalizumab (IPH2201) or Oleclumab (MEDI9447) to Durvalumab (MEDI4736) Plus Standard Radiation Therapy for Locally Advanced Non-small Cell Lung Cancer (NSCLC), ARCHON-1 Trial
Phase 1 Completed
26 enrolled 17 charts
A Comparison of Methods for Assisting Needle Angle Selection During Image-guided Tissue Biopsy
Phase 1 Completed
17 enrolled
Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer
Phase 1/2 Completed
45 enrolled 30 charts
Cisplatin/Carboplatin and Etoposide With or Without Nivolumab in Treating Patients With Extensive Stage Small Cell Lung Cancer
Phase 2 Completed
160 enrolled 12 charts
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
Completed
19,522 enrolled
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers
Phase 1/2 Completed
62 enrolled 29 charts
PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers
Phase 1/2 Completed
10 enrolled 13 charts
Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery
Phase 3 Completed
1,501 enrolled 16 charts
Erlotinib Hydrochloride and Onalespib Lactate in Treating Patients With Recurrent or Metastatic EGFR-Mutant Non-small Cell Lung Cancer
Phase 1/2 Completed
11 enrolled 11 charts
Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies
Phase 2 Completed
647 enrolled 17 charts
Sunitinib for Advanced Thymus Cancer Following Earlier Treatment
Phase 2 Completed
56 enrolled 15 charts
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
Phase 1 Completed
58 enrolled 17 charts
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples From Patients With Cancer to Study Drug Resistance
Completed
86 enrolled
Retrospective Analysis of a Drug-Metabolizing Genotype in Cancer Patients and Correlation With Pharmacokinetic and Pharmacodynamics Data
Completed
484 enrolled
Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-Mutated, Non-Small Cell Lung Cancer After Treatment With Osimertinib
Phase 2 Completed
37 enrolled 23 charts
Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer
Phase 1 Completed
FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer
Phase 2 Completed
Vaccine Therapy in Treating Patients With Metastatic Cancer
Phase 1 Completed
Iloprost in Preventing Lung Cancer in Former Smokers
Phase 1 Completed
34 enrolled
Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer
Phase 1/2 Completed
156 enrolled 13 charts
Cisplatin or Carboplatin, and Etoposide With or Without Sunitinib Malate in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Phase 1/2 Completed
156 enrolled 14 charts
Methoxyamine Hydrochloride, Pemetrexed Disodium, Cisplatin, and Radiation Therapy in Treating Patients With Stage IIIA-IV Non-small Cell Lung Cancer
Phase 1 Completed
17 enrolled
Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
Phase 2 Completed
130 enrolled 15 charts
A Case-Cohort Study of Hematopoietic Malignancies and Related Disorders and Lung Cancer in Benzene-Exposed Workers in China
Completed
3,260 enrolled
Olaparib in People With Malignant Mesothelioma
Phase 2 Completed
23 enrolled 16 charts
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Phase 2 Completed
11 enrolled 12 charts
Safety and Tolerability of a Modified Vaccinia Ankara (MVA)-Based Vaccine Modified to Express Brachyury and T-cell Costimulatory Molecules (MVA-Brachyury-TRICOM)
Phase 1 Completed
38 enrolled 20 charts
A Randomized Phase II Study of Cisplatin and Etoposide in Combination With Either Hedgehog Inhibitor GDC-0449 or IGF-1R MOAB IMC-A12 for Patients With Extensive Stage
Phase 2 Completed
168 enrolled 11 charts
Smoky Coal Exposure, Genetic Susceptibility, and Lung Cancer in Non-Smoking Women in China
Completed
3,720 enrolled
Multi-Targeted Recombinant Ad5 (CEA/MUC1/Brachyury) Based Immunotherapy Vaccine Regimen in People With Advanced Cancer
Phase 1 Completed
11 enrolled 18 charts
Genetic Epidemiology of Lung Cancer and Smoking
Completed
4,429 enrolled
Cigarette Smoking and Oral Microbiota
Completed
50 enrolled
Influence of Psychosocial Distress and Lifetime Trauma Exposure on Traumatic Stress Among Oncology Patients on Clinical Trials
Completed
55 enrolled
Genetic Epidemiology of Lung Cancer
Completed
6,356 enrolled
Prevention of Tumor Spread Due to Lung Cancer Surgery
Completed
41 enrolled
Evaluation of Cancer Care Coordination in the National Cancer Institutes Community Cancer Center Programs
Completed
1,079 enrolled
Testing a Spanish Version of a Patient Toxicity Questionnaire
Completed
112 enrolled
Prospective Analysis of Genotypes in Adults Undergoing Therapy for Lung Cancer
Completed
546 enrolled
Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies
Phase 1 Completed
34 enrolled
Azacitidine in Treating Patients With Previously Treated Advanced Non-Small Cell Lung Cancer
Phase 2 Completed
1 enrolled 5 charts
Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer
Phase 2 Completed
188 enrolled 16 charts
SS1P and Pentostatin Plus Cyclophosphamide for Mesothelioma
Phase 1/2 Completed
55 enrolled 22 charts
Cabozantinib-S-Malate and Erlotinib Hydrochloride in Treating Patients With Previously Treated Metastatic Non-Small Cell Lung Cancer
Phase 2 Completed
37 enrolled 13 charts
Azacitidine and Entinostat in Treating Patients With Recurrent Advanced Non-Small Cell Lung Cancer
Phase 1/2 Completed
94 enrolled 18 charts
Dasatinib in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Phase 2 Completed
35 enrolled 12 charts
A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancies
Phase 1 Completed
60 enrolled