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Recent Start date Enrollment

Phase 1 × Advanced Cancer × AZD 6244 × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Neoplasms 6 Melanoma 5 Carcinoma, Non-Small-Cell Lung 5 Solid Tumours 4 Lung Neoplasms 4 Rectal Neoplasms 3 Neurofibromatosis 1 3 Colonic Neoplasms 3 Breast Neoplasms 3 Biliary Tract Neoplasms 3 Neurofibroma, Plexiform 2 Neoplasm Metastasis 2 Colorectal Neoplasms 2 Uveal Melanoma 1 Solid Tumors 1 Renal Insufficiency 1 Primary Myelofibrosis 1 Parkinson Disease 4, Autosomal Dominant Lewy Body 1 Muscle Invasive Bladder Cancer 1 Locally Advanced or Metastatic Solid Tumors 1 Leukemia, Myelogenous, Chronic, BCR-ABL Positive 1 Kidney Neoplasms 1 Healthy Volunteers Pharmacokinetic Study 1 Gallbladder Neoplasms 1 Disease Progression 1 Cholangiocarcinoma 1 Advanced Non Small Cell Lung Cancer 1 Advanced Cancer 1 Adult Solid Neoplasm 1

Interventions

Nivolumab 6 Bevacizumab 5 temsirolimus 4 Sirolimus 4 Paclitaxel 4 Docetaxel 4 Pemetrexed 3 Ipilimumab 3 Erlotinib Hydrochloride 3 Carboplatin 3 apatinib 2 abemaciclib 2 Vorinostat 2 Magnetic Resonance Spectroscopy 2 Gemcitabine 2 Everolimus 2 Chlorogenic Acid 2 Cetuximab 2 ARRY-334543 2 6-(6-(1-methyl-1H-pyrazol-4-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-ylsulfanyl)quinoline 2 vorolanib 1 vistusertib 1 trametinib 1 tislelizumab 1 tilsotolimod 1 sargramostim 1 regorafenib 1 ralimetinib 1 pazopanib 1 palifosfamide lysine 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT00085787 2020-10-14

A Study of ARRY-142886 in Patients With Advanced Cancer

Array BioPharma

Phase 1 Completed

Advanced Cancer

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