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Phase 1 × Advanced Cancer × capivasertib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Conditions

Breast Neoplasms 3 Prostatic Neoplasms 2 Ovarian Neoplasms 2 Healthy Participants 2 Endometrial Neoplasms 2 Uterine Cervical Neoplasms 1 Triple Negative Breast Neoplasms 1 Squamous Cell Carcinoma of Head and Neck 1 Solid Tumour 1 Neoplasm Metastasis 1 Moderate Hepatic Impairment 1 Melanoma 1 Hereditary Sensory and Autonomic Neuropathies 1 Hematologic Neoplasms 1 Healthy Volunteers (Intended Indication: Metastatic Patients With Triple Negative or HR+ Breast Cancer, or Hormone Sensitive Prostate Cancer) 1 Chondrosarcoma 1 Advanced Solid Tumours 1 Advanced Solid Malignancy, 1 Advanced Solid Malignancy 1 Advanced Cancer 1

Interventions

Nivolumab 6 Bevacizumab 5 temsirolimus 4 Sirolimus 4 Paclitaxel 4 Docetaxel 4 Pemetrexed 3 Ipilimumab 3 Erlotinib Hydrochloride 3 Carboplatin 3 ARRY-334543 3 apatinib 2 abemaciclib 2 Vorinostat 2 Magnetic Resonance Spectroscopy 2 Gemcitabine 2 Everolimus 2 Chlorogenic Acid 2 Cetuximab 2 6-(6-(1-methyl-1H-pyrazol-4-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-ylsulfanyl)quinoline 2 vorolanib 1 vistusertib 1 trametinib 1 tislelizumab 1 tilsotolimod 1 sargramostim 1 regorafenib 1 ralimetinib 1 pazopanib 1 palifosfamide lysine 1

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT02338622 2024-09-26

ComPAKT

Royal Marsden NHS Foundation Trust

Phase 1 Completed

Advanced Cancer

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